Cycling in the heat: performance perspectives and cerebral challenges

Cellular mechanisms of muscle fatigue

1994 • 1,516 citations

Influence of body temperature on the development of fatigue during prolonged exercise in the heat

1999 • 1,064 citations

Human circulatory and thermoregulatory adaptations with heat acclimation and exercise in a hot, dry environment.

1993 • 691 citations

Effects of ambient temperature on the capacity to perform prolonged cycle exercise in man

1997 • 646 citations

Hyperthermia and central fatigue during prolonged exercise in humans

2001 • 596 citations

Heat acclimation, aerobic fitness, and hydration effects on tolerance during uncompensable heat stress

1998 • 402 citations

Human performance physiology and environmental medicine at terrestrial extremes

1988 • 400 citations

The cardiovascular challenge of exercising in the heat

2007 • 389 citations

Cerebral perturbations provoked by prolonged exercise

2004 • 374 citations

Models to Explain Fatigue during Prolonged Endurance Cycling

2005 • 372 citations

Dehydration markedly impairs cardiovascular function in hyperthermic endurance athletes during exercise

1997 • 371 citations

Impaired exercise performance in the heat is associated with an anticipatory reduction in skeletal muscle recruitment

2004 • 354 citations

Reductions in Systemic and Skeletal Muscle Blood Flow and Oxygen Delivery Limit Maximal Aerobic Capacity in Humans

2003 • 352 citations

Cerebral blood flow and metabolism during exercise: implications for fatigue

2007 • 340 citations

Die Regulation der Körpertemperatur bei Muskelarbeit¹

1938 • 324 citations

The rate of heat storage mediates an anticipatory reduction in exercise intensity during cycling at a fixed rating of perceived exertion

2006 • 316 citations

Rectal temperatures, weight losses, and sweat rates in marathon running.

1967 • 311 citations

Muscle blood flow is reduced with dehydration during prolonged exercise in humans

1998 • 304 citations

Control of mitochondrial and cellular respiration by oxygen

1995 • 303 citations

Perceived exertion is associated with an altered brain activity during exercise with progressive hyperthermia

2001 • 302 citations

Inadequate heat release from the human brain during prolonged exercise with hyperthermia

2002 • 301 citations

Hyperthermia and fatigue

2007 • 291 citations

The Science of Cycling

2005 • 290 citations

Muscle blood flow and muscle metabolism during exercise and heat stress

1990 • 256 citations

Effects of metabolic hyperthermia on performance during heavy prolonged exercise

1974 • 255 citations

Hyperthermia: a failure of the motor cortex and the muscle

2004 • 249 citations

Elevations in core and muscle temperature impairs repeated sprint performance

2005 • 235 citations

Passive hyperthermia reduces voluntary activation and isometric force production

2004 • 233 citations

Coupling between changes in human brain temperature and oxidative metabolism during prolonged visual stimulation

2000 • 228 citations

Cerebral Changes During Exercise in the Heat

2003 • 223 citations

Acute dopamine/noradrenaline reuptake inhibition enhances human exercise performance in warm, but not temperate conditions

2005 • 218 citations

Capillary-Oxygenation-Level-Dependent Near-Infrared Spectrometry in Frontal Lobe of Humans

2006 • 207 citations

Effects of hyperthermia on cerebral blood flow and metabolism during prolonged exercise in humans

2002 • 206 citations

Evidence for neuromuscular fatigue during high-intensity cycling in warm, humid conditions

2001 • 199 citations

Inadequate Cerebral Oxygen Delivery and Central Fatigue during Strenuous Exercise

2007 • 199 citations

Exercise in the heat is limited by a critical internal temperature

2000 • 189 citations

Brain and abdominal temperatures at fatigue in rats exercising in the heat

1998 • 182 citations

Temperature uniformity during hyperthermia: the impact of large vessels

1992 • 181 citations

Voluntary muscle activation is impaired by core temperature rather than local muscle temperature

2005 • 181 citations

Normal Average Value of Cerebral Blood Flow in Younger Adults is 50 ml/100 g/min

1985 • 163 citations

The Effects of Acute Dopamine Reuptake Inhibition on Performance

2008 • 162 citations

Effect of heat stress on muscle energy metabolism during exercise

1994 • 161 citations

The importance of volume in regulating gastric emptying

1991 • 155 citations

Middle cerebral artery blood velocity and cerebral blood flow and O2 uptake during dynamic exercise

1993 • 153 citations

Effects of marked hyperthermia with and without dehydration onV˙<scp>o</scp> ₂ kinetics during intense exercise

2001 • 151 citations

Evidence against a 40°C core temperature threshold for fatigue in humans

2009 • 148 citations

Middle cerebral artery blood velocity depends on cardiac output during exercise with a large muscle mass

1998 • 146 citations

Physiological Responses to Acute Exercise-Heat Stress

1988 • 141 citations

Gastric emptying, absorption, and carbohydrate oxidation during prolonged exercise

1992 • 139 citations

Selective brain cooling in humans: “fancy” or fact?

1993 • 137 citations

Mitochondrial respiration at low levels of oxygen and cytochrome c

2002 • 133 citations

Body temperatures and sweating during exhaustive exercise.

1972 • 119 citations

Effects of brain and trunk temperatures on exercise performance in goats

1986 • 118 citations

Comparing cycling world hour records, 1967???1996: modeling with empirical data

1999 • 110 citations

Olympics in Atlanta: a fight against physics

1996 • 105 citations

Limits to Exercise Performance in the Heat

1998 • 95 citations

Water and carbohydrate ingestion during prolonged exercise increase maximal neuromuscular power

2000 • 87 citations

Selective Brain Cooling in Mammals and Birds.

2001 • 85 citations

Separate and Combined Influences of Dehydration and Hyperthermia on Cardiovascular Responses to Exercise

1998 • 79 citations

Hyperprolactinaemia During Prolonged Exercise in the Heat: Evidence for a Centrally Mediated Component of Fatigue in Trained Cyclists

2002 • 77 citations

Hypohydration and prior heat stress exacerbates decreases in cerebral blood flow velocity during standing

2006 • 73 citations

Influence of Hydration Status on Thermoregulation and Cycling Hill Climbing

2007 • 69 citations

Respiratory heat loss at increased core temperature.

1974 • 69 citations

Limitations to Fluid Replacement During Exercise

1999 • 65 citations

Hyperthermia increases cerebral metabolic rate and blood flow in neonatal pigs

1988 • 62 citations

Heat induced fatigue and changes of the EEG is not related to reduced perfusion of the brain during prolonged exercise in humans

2004 • 56 citations

Reduced voluntary activation of human skeletal muscle during shortening and lengthening contractions in whole body hyperthermia

2004 • 52 citations

Lowering of skin temperature decreases isokinetic maximal force production independent of core temperature

2004 • 47 citations

THERMAL INTERCHANGES BETWEEN THE HUMAN BODY AND ITS ATMOSPHERIC ENVIRONMENT1

1937 • 39 citations

Common carotid blood temperature

1960 • 17 citations