R- and S-Warfarin inhibition of vitamin K and vitamin K 2,3-epoxide reductase activities in the rat.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Vitamin K Dependent Modifications of Glutamic Acid Residues in Prothrombin

1974 • 750 citations

Direct identification of the calcium-binding amino acid, gamma-carboxyglutamate, in mineralized tissue.

1975 • 741 citations

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.

1976 • 634 citations

A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S

1977 • 582 citations

The Mode of Action of Vitamin K

1974 • 527 citations

Mechanism of coumarin action: significance of vitamin K epoxide reductase inhibition

1978 • 385 citations

Vitamin K Metabolism and Vitamin K Dependent Proteins

1980 • 375 citations

Characterization of protein S, a .gamma.-carboxyglutamic acid containing protein from bovine and human plasma

1979 • 259 citations

Vitamin K-dependent carboxylase. Requirements of the rat liver microsomal enzyme system.

1976 • 172 citations

Studies on the 4-Hydroxycoumarins. XVII.^1a The Resolution and Absolute Configuration of Warfarin^1b

1961 • 153 citations

Isolation and characterization of a new metabolite of phylloquinone in the rat

1970 • 133 citations

NAD(P)H dehydrogenase and its role in the vitamin K (2-methyl-3-phytyl-1,4-naphthaquinone)-dependent carboxylation reaction

1978 • 128 citations

Changes in phylloquinone epoxidase activity related to prothrombin synthesis and microsomal clotting activity in the rat

1974 • 116 citations

Vitamin K-dependent γ-carboxyglutamic acid formation by kidney microsomes in vitro

1976 • 112 citations

Plasma half-lives, plasma metabolites and anticoagulant efficacies of the enantiomers of warfarin in man

1973 • 109 citations

Some characteristics of a vitamin K-dependent carboxylating system from rat liver microsomes

1976 • 105 citations

Warfarin and the Inhibition of Vitamin K Activity by an Oxide Metabolite

1972 • 102 citations

Vitamin K epoxidase: properties and relationship to prothrombin synthesis

1977 • 86 citations

Mechanism of warfarin resistance. Warfarin and the metabolism of vitamin K1

1973 • 75 citations

Mechanism of action of warfarin. Warfarin and metabolism of vitamin K1

1972 • 71 citations

Naphthoquinones of the Vitamin K₁ Type of Structure

1939 • 67 citations

The plasma half lives and the pharmacological effect of the enantiomers of warfarin in rats

1972 • 60 citations

Vitamin K1 hydroquinone formation catalyzed by a microsomal reductase system

1980 • 58 citations

An assay for coagulation factor VII using factor VII-depleted bovine plasma.

1974 • 56 citations

Vitamin K and Coumarin Anticoagulants: Dependence of Anticoagulant Effect on Inhibition of Vitamin K Transport

1969 • 51 citations

A Novel Method for the Quantitation of Warfarin and its Metabolites in Plasma

1979 • 46 citations

A Simple Assay Method for Factor x (Stuart-Prower Factor).

1962 • 43 citations

Characteristics of the vitamin K-dependent carboxylating system in human placenta

1979 • 41 citations

Mechanism of action of coumarins. Significance of vitamin K epoxide

1974 • 35 citations

Warfarin binding to microsomes isolated from normal and warfarin-resistant rat liver.

1972 • 25 citations

Effect of warfarin on the kinetics of the vitamin K-dependent clotting factors in rats.

1977 • 19 citations

Synthesis of clotting factors by a cell-free system from rat liver in response to the addition of vitamin K1 in vitro

1977 • 12 citations

Inhibition by warfarin enantiomers of prothrombin synthesis, protein carboxylation, and the regeneration of vitamin K from vitamin K epoxide

1981 • 10 citations

Simultaneous determination of plasma prothrombin and antithrombin III (heparin cofactor)

1975 • 4 citations