Diacylglycerol modulates binding and phosphorylation of the epidermal growth factor receptor.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

1980 • 1,317 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

1979 • 1,139 citations

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.

1984 • 715 citations

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

1983 • 705 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

1979 • 517 citations

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1981 • 492 citations

Enhancement of calcium uptake and phosphatidylinositol turnover by epidermal growth factor in A-431 cells

1981 • 426 citations

Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.

1982 • 417 citations

Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells.

1983 • 377 citations

Tumor-Promoting Phorbol Esters Inhibit Binding of Epidermal Growth Factor to Cellular Receptors

1978 • 355 citations

Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.

1984 • 331 citations

Inositol phospholipids in membrane function

1979 • 272 citations

Human transforming growth factors induce tyrosine phosphorylation of EGF receptors

1981 • 244 citations

Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

1984 • 219 citations

Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells.

1983 • 200 citations

Activation of calcium-activated, phospholipid-dependent protein kinase (protein kinase C) by new classes of tumor promoters: Teleocidin and debromoaplysiatoxin

1984 • 181 citations

Interactions between the receptors for platelet-derived growth factor and epidermal growth factor.

1983 • 168 citations

The tumor promoter 12‐0‐tetradecanoyl‐phorbol‐13‐acetate enhances the proliferative response of Balb/c‐3T3 cells to hormonal growth factors

1979 • 103 citations

Modulation of the epidermal growth factor receptor by platelet-derived growth factor and choleragen: Effects on mitogenesis

1982 • 76 citations

Effect of 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) on the growth inhibitory and increased phosphatidylinositol (PI) responses induced by epidermal growth factor (EGF) in A431 cells

1983 • 71 citations

Synergistic stimulation of early events and DNA synthesis by phorbol esters, polypeptide growth factors, and retinoids in cultured fibroblasts

1979 • 64 citations

Comparative effects of aplysiatoxin, debromoaplysiatoxin, and teleocidin on receptor binding and phospholipid metabolism.

1983 • 55 citations

Activation of calcium and phospholipid-dependent protein kinase by epidermal growth factor (EGF) in A431 cells: Attenuation by 12-0-tetradecanoylphorbol-13-acetate (TPA)

1982 • 40 citations

A specific phosphoprotein phosphatase acts on histone H1 phosphorylated by protein kinase C.

1983 • 28 citations