A Single Mutation of the Neurokinin-2 (NK2) Receptor Prevents Agonist-induced Desensitization

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

1987 • 1,189 citations

[6] Efficient site-directed mutagenesis using uracil-containing DNA

1991 • 644 citations

Protein kinases that phosphorylate activated G protein‐coupled receptors

1995 • 520 citations

Mammalian Tachykinin Receptors

1991 • 502 citations

Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.

1990 • 393 citations

Mechanisms of Rhodopsin Inactivation in Vivo as Revealed by a COOH-Terminal Truncation Mutant

1995 • 299 citations

The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2

1993 • 178 citations

Functional activity and regulation of human beta 2-adrenergic receptors expressed in Xenopus oocytes.

1987 • 137 citations

Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs.

1994 • 133 citations

Truncation of the receptor carboxyl terminus impairs agonist-dependent phosphorylation and desensitization of the alpha 1B-adrenergic receptor.

1994 • 132 citations

Receptor-selective, peptidase-resistant agonists at neurokinin NK-1 and NK-2 receptors: New tools for investigating neurokinin function

1991 • 109 citations

Structure-activity studies of neurokinin A

1989 • 106 citations

G Protein‐Coupled Receptor Kinases

1994 • 104 citations

C-terminal Truncation of the Neurokinin-2 Receptor Causes Enhanced and Sustained Agonist-induced Signaling

1995 • 76 citations

Receptors mediating tachykinin‐induced contractile responses in guinea‐pig trachea

1991 • 71 citations

Expression of receptors for cholecystokinin and other Ca2+-mobilizing hormones in Xenopus oocytes.

1988 • 68 citations

The ligand binding site of the neurokinin 2 receptor. Site-directed mutagenesis and identification of neurokinin A binding residues in the human neurokinin 2 receptor.

1994 • 62 citations

Attenuation of agonist‐induced desensitization of the rat substance P receptor by progressive truncation of the C‐terminus

1994 • 36 citations

Functional expression in vitro of bovine visual rhodopsin

1990 • 24 citations

Divergent conformational requirements for angiotensin II receptor internalization and signaling

1994 • 20 citations

Calcium influx and protein kinase Cα activation mediate arachidonic acid mobilization by the human NK‐2 receptor expressed in Chinese Hamster ovary cells

1994 • 18 citations

Regions of the Human Neurokinin A Receptor Involved in the Generation of Second Messengers and in Receptor Desensitization

1994 • 6 citations

Membrane Protein Models

1996 • 4 citations

Characterization of human ileum NK2 receptor stably expressed in Chinese hamster ovary cells using NK agonists

1992 • 3 citations