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Chemical and Biological Properties of Human Lymphotoxin

Data up to Jan 2025

Published1984
Citations20
References44

Total Citations Per Year

Abstract

References (44)

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Lysis of Homologous Cells by Sensitized Lymphocytes in Tissue Culture<xref ref-type="fn" rid="FN1">2</xref>

1961 • 282 citations

Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic Factor

1968 • 266 citations

Lymphocyte in vitro cytotoxicity: mechanisms of immune and nonimmune small lymphocyte mediated target L cell destruction

1968 • 230 citations

Cellular Antibodies in Kidney Homotransplantation

1960 • 206 citations

Ylmphocyte in Vitro Cytotoxicity: Mechanisms of Immune and Non-Immune Small Lymphocyte Mediated Target L Cell Destruction

1968 • 191 citations

Lymphocyte in vitro cytotoxicity: characterization of human lymphotoxin.

1968 • 164 citations

Studies on the mechanism of natural killer (NK) cell-mediated cytotoxicity (CMC). I. Release of cytotoxic factors specific for NK-sensitive target cells (NKCF) during co-culture of NK effector cells with NK target cells.

1982 • 153 citations

Production of Lymphotoxin and Migration Inhibitory Factor by Established Human Lymphocytic Cell Lines

1970 • 130 citations

Cell-Mediated Immunity in Vitro: A Highly Sensitive Assay for Human Lymphotoxin

1974 • 110 citations

Studies on the mechanism of natural killer cytotoxicity. II. coculture of human PBL with NK-sensitive or resistant cell lines stimulates release of natural killer cytotoxic factors (NKCF) selectively cytotoxic to NK-sensitive target cells.

1983 • 86 citations

The human LT system

1978 • 78 citations

Lymphocyte in vitro cytotoxicity: Characterization of mouse lymphotoxin

1970 • 70 citations

The in vitro induction and release of a cell toxin by immune C57B1/6 mouse peritoneal macrophages

1972 • 67 citations

Cytotoxic activity of lymphocytes. VI. Heterogeneity of cytotoxins in supernatants of mitogen-activated lymphocytes.

1976 • 66 citations

In vitro synergism between interferons and human lymphotoxin: enhancement of lymphotoxin-induced target cell killing.

1983 • 64 citations

Lymphotoxin ? An immunologic hormone with anticarcinogenic and antitumor activity

1982 • 56 citations

Purification of Human Lymphotoxin

1972 • 48 citations

Cytotoxic Activity of Lymphocytes

1976 • 45 citations

Human Lymphotoxin Obtained from Established Lymphoid Lines: Purification Characteristics and Inhibition by Anti-Immunoglobulin

1974 • 41 citations

Studies on in vitro models of cellular immunity: The role of T and B cells in the secretion of lymphotoxin

1973 • 40 citations

Characteristics of a Cytotoxin (“Lymphotoxin”) Produced by Stimulation of Human Lymphoid Tissue

1973 • 39 citations

The human LT system

1978 • 37 citations

Lymphokine properties of a lymphoid cultured cell supernatant fraction active in promoting tumor regression

1976 • 36 citations

Lymphotoxin. A review and analysis.

1976 • 35 citations

Lymphotoxin: Properties, role and mode of action

1981 • 31 citations

Lymphotoxin cytotoxicity, a combination of cytolytic and cytostatic cellular responses

1981 • 25 citations

Cytotoxic activity of lymphocytes. I. Assay for cytotoxicity by rubidium exchange at isotopic equilibrium.

1972 • 23 citations

Human Lymphotoxin: Purification and Some Properties

1973 • 22 citations

The role of lymphotoxin in target cell destruction induced by mitogen-activated human lymphocytes in vitro. II. The correlation of temperature and trypsin-sensitive phases of lymphotoxin-induced and lymphocyte-mediated cytotoxicity.

1976 • 19 citations

The Role of Lymphotoxin in Target Cell Destruction Induced by Mitogen-Activated Human Lymphocytes in Vitro

1976 • 15 citations

Human and murine lymphotoxins as a multicomponent system: Progress in purification of the human αL component

1980 • 14 citations

The human LT system

1979 • 14 citations

A rapid quantitative assay for lymphotoxin

1977 • 14 citations

Cytotoxic activity of lymphocytes

1979 • 12 citations

Purification of human alpha-light class lymphotoxin to electrophoretic homogeneity

1981 • 12 citations

The Lymphokines: Biochemistry and Biological Activity

1981 • 10 citations

Cytotoxic Activity of Lymphocytes

1972 • 10 citations

The Effect of Antibodies to Complement Components C2, C3 and C5 on the Production and Action of Lymphotoxin

1972 • 9 citations

Human lymphotoxins: Purification to electrophoretic homogeneity of the αH receptor-bearing class

1981 • 7 citations

Cytotoxic activity of purified guinea pig lymphotoxin against various cell lines.

1976 • 6 citations

A STANDARDIZED AUTOMATED COMPUTER ASSISTED MICRO-ASSAY FOR LYMPHOTOXIN

1982 • 3 citations

PRE-CLINICAL AND PHASE 1 CLINICAL TRIALS WITH LYMPHOTOXIN

1982 • 3 citations

Lymphotoxins

1981 • 3 citations

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