Active suppression in orally tolerized rats coincides within situtransforming growth factor-beta (TGF-β) expression in the draining lymph nodes

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

Peripheral deletion of antigen-reactive T cells in oral tolerance

1995 • 775 citations

Oral tolerance: immune mechanisms and treatment of autoimmune diseases

1997 • 757 citations

Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering.

1992 • 734 citations

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.

1992 • 726 citations

Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.

1994 • 643 citations

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes.

1989 • 567 citations

Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy.

1991 • 450 citations

Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin

1993 • 233 citations

High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-beta secretion and T cell apoptosis.

1996 • 221 citations

The induction of tolerance to a soluble protein antigen by oral administration.

1974 • 211 citations

Oral tolerance in experimental autoimmune uveoretinitis. Distinct mechanisms of resistance are induced by low dose vs high dose feeding protocols.

1993 • 184 citations

In Situ Immune Response in Gut-Associated Lymphoid Tissue (GALT) Following Oral Antigen in TCR-Transgenic Mice

1998 • 145 citations

The Transforming Growth Factor-Beta Family

1990 • 137 citations

Inhibition of specific immune responses by feeding protein antigens. IV. Evidence for tolerance and specific active suppression of cell-mediated immune responses to ovalbumin.

1979 • 131 citations

Inhibition of Specific Immune Responses by Feeding Protein Antigens

1977 • 126 citations

In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: Anergy in the absence of suppression

1994 • 113 citations

Generation of an inhibitory circuit involving CD8+ T cells, IL-2, and NK cell-derived TGF-beta: contrasting effects of anti-CD2 and anti-CD3.

1998 • 99 citations

Inhibition of Specific Immune Responses by Feeding Protein Antigens

1979 • 93 citations

TGF-beta induced by oral tolerance ameliorates experimental tracheal eosinophilia.

1997 • 90 citations

Generation of an Inhibitory Circuit Involving CD8+ T Cells, IL-2, and NK Cell-Derived TGF-β: Contrasting Effects of Anti-CD2 and Anti-CD3

1998 • 78 citations

Difference between bacterial and food antigens in mucosal immunogenicity

1989 • 73 citations

Effects of antigen-feeding on intestinal and systemic immune responses. II. Suppression of delayed-type hypersensitivity reactions.

1978 • 64 citations

Oral Tolerization Leads to Active Suppression and Bystander Tolerance in Adult Rats while Anergy Dominates in Young Rats

1996 • 50 citations

Cytokine mRNA expression profiles in rats infected with the intestinal nematode Nippostrongylus brasiliensis

1995 • 46 citations

Effects of Antigen-Feeding on Intestinal and Systemic Immune Responses

1978 • 44 citations

Inactivation of Th1 and Th2 Cells by Feeding Ovalbumina

1996 • 39 citations

Bystander suppression of the immune response to human serum albumin in rats fed ovalbumin.

1995 • 34 citations