Specificities of autoinhibitory domain peptides for four protein kinases. Implications for intact cell studies of protein kinase function.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

Protein Kinase C Contains a Pseudosubstrate Prototope in Its Regulatory Domain

1987 • 1,020 citations

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

1989 • 1,015 citations

Regulation of brain Type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: A Ca2+-triggered molecular switch

1986 • 856 citations

Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.

1977 • 844 citations

[1] Assays of protein kinase

1983 • 832 citations

Purification and characterization of smooth muscle myosin light chain kinase.

1981 • 501 citations

Protein kinases. Regulation by autoinhibitory domains.

1990 • 322 citations

The influence of basic residues on the substrate specificity of protein kinase C.

1987 • 287 citations

Primary Structural Determinants Essential for Potent Inhibition of cAMP-dependent Protein Kinase by Inhibitory Peptides Corresponding to the Active Portion of the Heat-Stable Inhibitor Protein

1989 • 278 citations

Calcium/calmodulin-dependent protein kinase II. Characterization of distinct calmodulin binding and inhibitory domains.

1988 • 256 citations

Substrate specificity of a multifunctional calmodulin-dependent protein kinase.

1985 • 243 citations

The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence.

1987 • 241 citations

Purification and Characterization of a Ca²⁺‐ and Calmodulin‐Dependent Protein Kinase from Rat Brain

1982 • 235 citations

A synthetic peptide substrate specific for casein kinase II.

1985 • 202 citations

Molecular basis of insulin action

1986 • 201 citations

Isolation and characterization of two distinct forms of protein kinase C.

1987 • 192 citations

Ca²⁺, Calmodulin‐Dependent Regulation of Microtubule Formation via Phosphorylation of Microtubule‐Associated Protein 2, τ Factor, and Tubulin, and Comparison with the Cyclic AMP‐Dependent Phosphorylation

1985 • 183 citations

Regulatory Domain of Calcium/Calmodulin-dependent Protein Kinase II

1989 • 177 citations

Calcium · calmodulin-dependent protein kinase II and calcium · phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide

1987 • 173 citations

Regulatory interactions of the calmodulin-binding, inhibitory, and autophosphorylation domains of Ca2+/calmodulin-dependent protein kinase II.

1988 • 159 citations

Proteolysis of smooth muscle myosin light chain kinase. Formation of inactive and calmodulin-independent fragments.

1987 • 156 citations

Effects of modulators of myosin light-chain kinase activity in single smooth muscle cells

1989 • 153 citations

Autoregulation of Enzymes by Pseudosubstrate Prototopes: Myosin Light Chain Kinase

1988 • 152 citations

Specific inhibitors of protein kinase C block transmitter-induced modulation of sensory neuron calcium current

1989 • 130 citations

Rabbit skeletal muscle myosin light chain kinase. The calmodulin binding domain as a potential active site-directed inhibitory domain.

1987 • 122 citations

Generation of the Ca2+-independent form of Ca2+/calmodulin-dependent protein kinase II in cerebellar granule cells

1989 • 101 citations

Spatial requirements for location of basic residues in peptide substrates for smooth muscle myosin light chain kinase.

1985 • 88 citations

Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals.

1988 • 81 citations

Pseudosubstrates turn off protein kinases

1988 • 81 citations

Brain Receptor Methodologies

1984 • 73 citations

Use of a resin-bound synthetic peptide for identifying a neutralizing antigenic determinant associated with the human immunodeficiency virus envelope.

1987 • 59 citations

Regulation of the Actin‐Activated Mg‐ATPase of Brain Myosin via Phosphorylation by the Brain Ca²⁺, Calmodulin‐Dependent Protein Kinases

1986 • 33 citations

Regulation of protein kinases by pseudosubstrate prototopes

1989 • 32 citations

Characterization of the phosphorylation of rat mammary ATP‐citrate lyase and acetyl‐CoA carboxylase by Ca²⁺ and calmodulin‐dependent multiprotein kinase and Ca²⁺ and phospholipid‐dependent protein kinase

1986 • 27 citations