Sister chromatid exchange analysis.

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

1975 • 7,413 citations

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

New Giemsa method for the differential staining of sister chromatids

1974 • 3,198 citations

Cytological detection of mutagen–carcinogen exposure by sister chromatid exchange

1975 • 1,333 citations

Evolution of Repeated DNA Sequences by Unequal Crossover

1976 • 1,208 citations

A Manyfold Increase in Sister Chromatid Exchanges in Bloom's Syndrome Lymphocytes

1974 • 934 citations

Microfluorometric Detection of Deoxyribonucleic Acid Replication in Human Metaphase Chromosomes

1973 • 838 citations

THE ORGANIZATION AND DUPLICATION OF CHROMOSOMES AS REVEALED BY AUTORADIOGRAPHIC STUDIES USING TRITIUM-LABELED THYMIDINEE

1957 • 824 citations

A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.

1973 • 533 citations

Sister chromatid exchange as an indicator of mutagenesis

1978 • 504 citations

Sister Chromatid Exchanges, Indices of Human Chromosome Damage and Repair: Detection by Fluorescence and Induction by Mitomycin C

1974 • 491 citations

Chromosome tests with 134 compounds on Chinese hamster cells in vitro — A screening for chemical carcinogens

1977 • 445 citations

Factors involved in differential giemsa-staining of sister chromatids

1978 • 420 citations

Defective excision repair of γ-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts

1976 • 365 citations

Giemsa technique for the detection of sister chromatid exchanges

1974 • 363 citations

Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens

1976 • 340 citations

Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells

1976 • 331 citations

Chromosome Aberrations and Sister Chromatid Exchanges in Chinese Hamster Cells Exposed to Various Chemicals 2

1977 • 330 citations

Sister chromatid exchanges induced in chinese hamster cells by UV irradiation of different stages of the cell cycle: The necessity for cells to pass through S

1974 • 312 citations

Spontaneous sister chromatid exchanges detected by a BUdR-labelling method

1974 • 309 citations

The segregation of DNA in epithelial stem cells

1978 • 299 citations

Cross-link repair in human cells and its possible defect in Fanconi's anemia cells

1977 • 294 citations

Simple differential Giemsa staining of sister chromatids after treatment with photosensitive dyes and exposure to light and the mechanism of staining

1975 • 285 citations

Malignant neoplasms in the families of patients with ataxia-telangiectasia.

1976 • 285 citations

Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia.

1975 • 266 citations

Fanconi's Anaemia in the Genetics of Neoplasia

1971 • 263 citations

Testing of known carcinogens and noncarcinogens for their ability to induce unscheduled DNA synthesis in HeLa cells.

1978 • 245 citations

Sister chromatid exchanges induced by mutagenic carcinogens in normal and xeroderma pigmentosum cells

1977 • 238 citations

Differential spiralization along mammalian mitotic chromosomes

1972 • 220 citations

Sister chromatid exchange as an assay for genetic damage induced by mutagen-carcinogens. II. In vitro test for compounds requiring metabolic activation

1976 • 216 citations

Identification of ataxia telangiectasia heterozygotes, a cancer prone population

1978 • 211 citations

Tumor promoter induces sister chromatid exchanges: relevance to mechanisms of carcinogenesis.

1978 • 206 citations

Localization of Sister Chromatid Exchanges in Human Chromosomes

1974 • 205 citations

Induction of sister chromatid exchanges by chemical mutagens and its possible relevance to DNA repair

1974 • 197 citations

Cytological Evidence for Crossing-Over in vitro in Human Lymphoid Cells

1964 • 196 citations

Increased frequency of sister chromatid exchanges in cigarette smokers

2009 • 190 citations

Induction of sister chromatid exchanges by UV light and its inhibition by caffeine

1973 • 180 citations

Sister chromatid exchange in human chromosomes from normal individuals and patients with ataxia telangiectasia

1975 • 179 citations

CHROMOSOME ABERRATIONS AND SISTER-CHROMATID EXCHANGE IN WORKERS IN CHEMICAL LABORATORIES AND A ROTOPRINTING FACTORY AND IN CHILDREN OF WOMEN LABORATORY WORKERS

1977 • 171 citations

Optical studies of the interaction of 4?-6-diamidino-2-phenylindole with DNA and metaphase chromosomes

1977 • 166 citations

Ultraviolet light sensitivity and delayed DNA-chain maturation in Bloom's syndrome fibroblasts

1977 • 162 citations

Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence.

1975 • 159 citations

Sister Chromatid Exchange and Chromosome Aberration Analysis With the Use of Several Carcinogens and Noncarcinogens: Brief Communication

1977 • 157 citations

Analysis of sister chromatid exchange formation in vivo in mouse spermatogonia as a new test system for environmental mutagens

1976 • 155 citations

Differential chromatid staining by in vivo treatment as a mutagenicity test system

1976 • 150 citations

Mechanisms for sister chromatid exchanges and their relation to the production of chromosomal aberrations

1977 • 141 citations

Sister chromatid exchange studies for monitoring DNA damage and repair capacity after cytostatics in vitro and in lymphocytes of leukaemic patients under cytostatic therapy

1978 • 140 citations

Cultivated Cells from Diagnostic Amniocentesis in Second Trimester Pregnancies. I. Clonal Morphology and Growth Potential

1974 • 134 citations

In vivo BrdU-33258 Hoechst analysis of DNA replication kinetics and sister chromatid exchange formation in mouse somatic and meiotic cells

1976 • 118 citations

Induction of sister chromatid exchanges in xeroderma pigmentosum cells after exposure to ultraviolet light

1977 • 116 citations

A protease inhibitor blocks SOS functions in Escherichia coli: antipain prevents lambda repressor inactivation, ultraviolet mutagenesis, and filamentous growth.

1977 • 112 citations

Bromodeoxyuridine tablet methodology for in vivo

1978 • 111 citations

Direct evidence for the role of incorporated BUdR in the induction of sister chromatid exchanges

1978 • 109 citations

Satellite DNA and heterochromatin variants: The case for unequal mitotic crossing over

1979 • 109 citations

Repair of DNA damaged by alkylating carcinogens is defective in xeroderma pigmentosum-derived fibroblasts

1977 • 109 citations

Effect of tumor promoters, protease inhibitors, and repair processes on x-ray-induced sister chromatid exchanges in mouse cells.

1979 • 104 citations

Replication bypass model of sister chromatid exchanges and implications for Bloom's Syndrome and Fanconi's anemia

1977 • 103 citations

Vitamin C is positive in the DNA synthesis inhibition and sister-chromatid exchange tests

1979 • 97 citations

Analysis of the frequency and distribution of sister chromatid exchanges in cultured human lymphocytes

1977 • 97 citations

Possible role of DNA synthesis in formation of sister chromatid exchanges

1974 • 97 citations

Distribution of sister chromatid exchanges in the euchromatin and heterochromatin of the Indian muntjac

1975 • 95 citations

Evidence derived from sister chromatid exchanges of restricted rejoining of chromatid subunits

1975 • 91 citations

Differential fluorescence of sister chromatids in chicken embryos exposed to 5-bromodeoxyuridine

1975 • 89 citations

Insights on chromosome structure from sister chromatid exchange ratios and the lack of both isolabelling and heterolabelling as determined by the FPG technique

1975 • 88 citations

Induction of sister chromatid exchanges in chromosomes of rat kangaroo cells by tritium incorporated into DNA

1972 • 88 citations

Induction of long-lived chromosome damage, as manifested by sister-chromatid exchange, in lymphocytes of animals exposed to mitomycin-C

1978 • 88 citations

REPLICATION, RECOMBINATION, AND CHIASMATA IN GONIAEA AUSTRALASIAE (ORTHOPTERA:ACRIDIDAE)

1970 • 86 citations

A study of unscheduled DNA synthesis induced by X-rays in the germ cells of male mice

1978 • 85 citations

Carcinogen-induced chromosome breakage in Fanconi's anaemia heterozygous cells

1978 • 85 citations

Chromatid exchanges in ataxia telangiectasia, Bloom syndrome, Werner syndrome, and xeroderrna pigmentosum

1976 • 83 citations

The effect of triated thymidine on sister chromatid exchange in a ring chromosome

1969 • 81 citations

Characterization of sister chromatid exchange induction by 8-methoxypsoralen plus near UV light

1978 • 80 citations

Xeroderma Pigmentosum: A Rapid Sensitive Method for Prenatal Diagnosis

1971 • 79 citations

Microfluorometric detection of asymmetry in the centromeric region of mouse chromosomes

1974 • 77 citations

Factors influencing the frequency of mitomycin C-induced sister-chromatid exchanges in 5-bromodeoxyuridine-substituted human lymphocytes in culture

1978 • 72 citations

Lateral asymmetry in the fluorescence of human Y chromosomes stained with 33 258 Hoechst

1974 • 72 citations

Repair of mitomycin C damage to DNA in mammalian cells and its impairment in Fanconi's anemia cells

1975 • 72 citations

Chromatidaustausch und Heterochromatinver�nderungen menschlicher Chromosomen nach BUdR-Markierung

1974 • 71 citations

Sister chromatid differentiation and exchanges in adult mudminnows (Umbra limi) after in vivo exposure to 5-bromodeoxyuridine

1976 • 66 citations

Lateral asymmetry in human constitutive heterochromatin

1975 • 66 citations

Deoxyribonucleic acid replication in single cells and chromosomes by immunologic techniques.

1976 • 64 citations

Inhibitory effects of selenium on 1,2- dimethylhydrazine and methylazoxymethanol colon carcinogenesis.Correlative studies on selenium effects on the mutagenicity and sister chromatid exchange rates of selected carcinogens

1977 • 61 citations

Bloom's syndrome: DNA replication in cultured fibroblasts and lymphocytes

1977 • 61 citations

Sister chromatid exchange in lymphocytes from patients with malignant lymphoma

1978 • 60 citations

The inhibitory effect of cysteine on the mutagenic activities of several carcinogens

1978 • 60 citations

Ataxia telangiectasia: The effects of chemical mutagens and x-rays on sister chromatid exchanges in blood lymphocytes

1977 • 57 citations

Cytological detection of crossing-over in BUdR substituted meiotic chromosomes using the fluorescent plus Giemsa technique

1978 • 57 citations

Normalisation of sister chromatid exchange frequencies in Bloom's syndrome by euploid cell hybridisation

1979 • 57 citations

Effect of cocultivation on sister chromatid exchange frequencies in Bloom's syndrome and normal fibroblast cells

1978 • 56 citations

The effect of a tumor promoter, 12-O-tetradecanoyl-phorbol-13-acetate (TPA), on sister-chromatid exchange formation in cultured Chinese hamster cells

1979 • 56 citations

Induction of sister chromatid exchanges by transformation with simian virus 40.

1978 • 56 citations

Study of Mitomycin C-induced chromosomal exchange

1976 • 54 citations

Sister chromatid exchanges and aging

1979 • 51 citations

Differential giemsa staining of sister chromatids after extraction with acids

1977 • 50 citations

LACK OF SPONTANEOUS SISTER CHROMATID EXCHANGES IN SOMATIC CELLS OF DROSOPHILA MELANOGASTER

1979 • 50 citations

Analysis of the frequency of sister chromatid exchange in different regions of chromosomes of the kangaroo rat (Dipodomys ordii)

1976 • 50 citations

Ultraviolet light-induced sister chromatid exchanges in xeroderma pigmentosum and in Cockayne's syndrome lymphocyte cell lines.

1978 • 48 citations

Detection by density equilibrium centrifugation of recombinant-like DNA molecules in somatic mammalian cells

1975 • 45 citations

Induction of a high incidence of damage to the X chromosomes of Rattus (Mastomys) natalensis by base analogues, viruses, and carcinogens

1967 • 44 citations

Chromosome breaks in Werner's syndrome and their prevention in vitro by radical-scavenging enzymes

2009 • 42 citations

Sister-chromatid exchange induced by X-ray of human lymphocytes and the effect of l-cysteine

1978 • 42 citations

Preliminary communication: prenatal detection of the Fanconi Anemia gene by cytogenetic methods.

1979 • 41 citations

The fate of U.V.-induced lesions affecting SCEs, chromosome abberrations and survival of CHO cells arrested by deprivation of arginine

1979 • 41 citations

Suppression of the frequencies of sister chromatid exchanges in Bloom's syndrome fibroblasts by co-cultivation with Chinese hamster cells

1978 • 40 citations

Psoralen/UVA treatment and chromosomes

1977 • 40 citations

Chromosome aberrations and unscheduled DNA synthesis in X- and UV-irradiated lymphocytes from a boy with Bloom’s syndrome and a man with xeroderma pigmentosum

1978 • 40 citations

BrdU-dye characterization of late replication and meiotic recombination in Armenian hamster germ cells

1979 • 40 citations

Effects of alkylating agents on lymphocytes from controls and from patients with Fanconi's anemia

1979 • 39 citations

Differential rates of sister chromatid exchanges between euchromatin and heterochromatin

1976 • 38 citations

Caffeine inhibition of prereplication repair of mitomycin C-induced DNA damage in human peripheral lymphocytes

1978 • 37 citations

Evidence for the formation of hybrid DNA during mitotic recombination in Chinese hamster cells

1976 • 36 citations

Frequency of sister chromatid exchanges in Bloom syndrome fibroblasts reduced by cocultivation with normal cells

1979 • 36 citations

In utero sister chromatid exchange analysis for detection of transplacental mutagens

1979 • 35 citations

Asymmetrical C-bands and satellite DNA in man

1975 • 34 citations

Further analysis of the replication bypass model for sister chromatid exchange

1979 • 33 citations

Effects of caffeine on sister-chromatid exchanges (SCE) in vivo

1979 • 32 citations

UV-light induced sister chromatid exchanges in xeroderma pigmentosum lymphocytes

1977 • 29 citations

Meiotic crossing over exchange in the female mouse visualised by BUdR substitution

1979 • 29 citations

Increased sister chromatid exchange in megaloblastic anaemia - Studies on bone marrow cells and lymphocytes

2009 • 28 citations

Sister chromatid exchanges in human lymphoid cell lines cultured in diffusion chambers in mice

1978 • 27 citations

Mitotic chiasmata and other quadriradials in mitomycin C-treated Bloom's syndrome lymphocytes

1978 • 27 citations

Sister chromatid exchanges in ataxia telangiectasia

1976 • 26 citations

Aging and sister chromatid exchange I. The effect of aging on mitomycin-C induced sister chromatid exchange frequencies in mouse and rat bone marrow cells in vivo

1978 • 24 citations

“Reverse” differential staining of sister chromatids

1977 • 21 citations

Normal rate of sister chromatid exchange in Down syndrome

1977 • 18 citations

Reciprocal Giemsa staining of late DNA replicating regions produced by low and high pH sodium phosphate

1978 • 17 citations

Inhibition of chemically induced sister chromatid exchanges by elastatinal

1979 • 14 citations

Reverse differential staining of sister chromatids after substitution with BUdR and incubation in sodium phosphate solution

1978 • 14 citations

Isolabeling of the long arm of the human Y chromosome demonstrated by the FPG technique

1978 • 12 citations

Search for DNA interchange corresponding to sister chromatid exchanges in Chinese hamster ovary cells

1978 • 12 citations

Increased amounts of hybrid (heavy/heavy) DNA in bloom's syndrome fibroblasts

1978 • 11 citations