Selective molybdate-directed covalent modification of sulfhydryl groups in the steroid-binding versus the DNA-binding domain of the glucocorticoid receptor.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA

1986 • 722 citations

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

1988 • 522 citations

Evidence That the 90-kDa Heat Shock Protein Is Necessary for the Steroid Binding Conformation of the L Cell Glucocorticoid Receptor

1989 • 394 citations

The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild-type and mutant receptor proteins.

1986 • 392 citations

Evidence that the endogenous heat-stable glucocorticoid receptor-activating factor is thioredoxin.

1983 • 309 citations

Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor.

1987 • 299 citations

A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex.

1988 • 267 citations

Characterization of a Monoclonal Antibody to the Rat Liver Glucocorticoid Receptor*

1984 • 263 citations

Thio and seleno compounds of the transition metals with the do configuration

1973 • 216 citations

Glucocorticoid-binding Proteins of Rat Liver Cytosol

1972 • 206 citations

Characterization of the purified activated glucocorticoid receptor from rat liver cytosol.

1984 • 186 citations

Proof that the endogenous, heat-stable glucocorticoid receptor-activating factor is thioredoxin.

1985 • 158 citations

Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate.

1987 • 125 citations

Interaction of the Mr = 90,000 heat shock protein with the steroid-binding domain of the glucocorticoid receptor.

1988 • 123 citations

Identification of hormone-interacting amino acid residues within the steroid-binding domain of the glucocorticoid receptor in relation to other steroid hormone receptors.

1988 • 121 citations

Domain structure of the glucocorticoid receptor protein.

1987 • 121 citations

Specific covalent modification of thiols: Applications in the study of enzymes and other biomolecules

1979 • 118 citations

The involvement of receptor sulphydryl groups in the binding of steroids to the cytoplasmic glucocorticoid receptor from rat thymus

1975 • 93 citations

Monoclonal antibody to the rat glucocorticoid receptor. Relationship between the immunoreactive and DNA-binding domain.

1985 • 88 citations

Glucocorticoid receptor phosphorylation, transformation, and DNA binding.

1987 • 86 citations

Limited proteolysis of covalently labeled glucocorticoid receptors as a probe of receptor structure

1984 • 85 citations

Direct Evidence for Intra- and Intermolecular Disulfide Bond Formation in the Human Glucocorticoid Receptor

1989 • 80 citations

Reversible dissociation of steroid hormone x receptor complexes by mercurial reagents.

1980 • 73 citations

Sulfhydryl-modifying reagents reversibly inhibit binding of glucocorticoid-receptor complexes to DNA-cellulose

1984 • 71 citations

Localization of phosphorylation sites with respect to the functional domains of the mouse L cell glucocorticoid receptor.

1988 • 70 citations

The role of sulfhydryl groups in permitting transformation and DNA binding of the glucocorticoid receptor.

1987 • 64 citations

Chemical cross-linking of heteromeric glucocorticoid receptors

1988 • 64 citations

Steroid binding to hepatoma tissue culture cell glucocorticoid receptors involves at least two sulfhydryl groups.

1988 • 49 citations

Identification of cysteine-644 as the covalent site of attachment of dexamethasone 21-mesylate to murine glucocorticoid receptors in WEHI-7 cells

1988 • 46 citations

Evidence for distinct sulfhydryl groups associated with steroid- and DNA-binding domains of rat thymus glucocorticoid receptors

1984 • 45 citations

Hydrogen peroxide stabilizes the steroid-binding state of rat liver glucocorticoid receptors by promoting disulfide bond formation

1988 • 41 citations

The possible role of disulfide bond reduction in transformation of the 10 S androgen receptor.

1986 • 36 citations

Effect of chemical inactivating agents on glucocorticoid receptor proteins in mouse and hamster cells.

1975 • 36 citations

Inhibition of glucocorticoid receptor transformation, subunit dissociation, and temperature-dependent inactivation by various N-substituted maleimides

1988 • 17 citations

Inactivation of unbound rat liver glucocorticoid receptor by N-alkylmaleimides at sub-zero temperatures

1984 • 12 citations