Phosphoenzyme formation from ATP in the ATPase of sarcoplasmic reticulum. Effect of KCl or ATP and slow dissociation of ATP from precursor enzyme-ATP complex.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Determination of Inorganic Phosphate

1949 • 1,485 citations

Activation by Adenosine Triphosphate in the Phosphorylation Kinetics of Sodium and Potassium Ion Transport Adenosine Triphosphatase

1972 • 826 citations

Energy Interconversion by the Ca2+-Dependent ATPase of the Sarcoplasmic Reticulum

1979 • 718 citations

ADENOSINE TRIPHOSPHATE-LINKED CONCENTRATION OF CALCIUM IONS IN A PARTICULATE FRACTION OF RABBIT MUSCLE

1962 • 701 citations

Molecular mechanism of active calcium transport by sarcoplasmic reticulum.

1978 • 586 citations

Rate of Calcium Binding and Uptake in Normal Animal and Failing Human Cardiac Muscle: MEMBRANE VESICLES (RELAXING SYSTEM) AND MITOCHONDRIA

1969 • 521 citations

Calcium Transport in Sarcoplasmic Reticulum

1975 • 328 citations

The Phosphorylation of the Membranal Protein of the Sarcoplasmic Vesicles during Active Calcium Transport

2005 • 263 citations

Phosphorylation of the sarcoplasmic reticulum membrane by orthophosphate. Inhibition by calcium ions

1973 • 243 citations

Reaction Mechanism of the Ca2+-dependent ATPase of Sarcoplasmic Reticulum from Skeletal Muscle: V. Vectorial Requirements for Calcium and Magnesium Ions of Three Partial Reactions of ATPase: Formation and Decomposition of a Phosphorylated Intermediate and ATP-Formation from ADP and the Intermediate*

1971 • 237 citations

ATP and Ca2+ binding by the Ca2+ pump protein of sarcoplasmic reticulum

1973 • 225 citations

The reversibility of the sarcoplasmic calcium pump

1978 • 222 citations

[12] Stability constants for biologically important metal-ligand complexes

1979 • 217 citations

Transient state kinetic studies of sarcoplasmic reticulum adenosine triphosphatase.

1975 • 212 citations

Occurrence and Characteristics of a Rapid Exchange of Phosphate Oxygens Catalyzed by Sarcoplasmic Reticulum Vesicles

1973 • 206 citations

[118] 32P-labeling of a (Na+ + K+)-ATPase intermediate

1967 • 203 citations

Sarcoplasmic reticulum. VII. Properties of a phosphoprotein intermediate implicated in calcium transport.

1969 • 198 citations

Occlusion of Divalent Cations in the Phosphorylated Calcium Pump of Sarcoplasmic Reticulum

1980 • 191 citations

Sarcoplasmic Reticulum

1969 • 188 citations

Cation Flux Across Biomembranes

1979 • 168 citations

Transient kinetics of Ca2+ transport of sarcoplasmic reticulum. A comparison of cardiac and skeletal muscle.

1978 • 155 citations

A study of the phosphorylated intermediate of sarcoplasmic reticulum atpase

1970 • 154 citations

Formation of adenosine triphosphate from Pi and adenosine diphosphate by purified Ca-2+-adenosine triphosphatase.

1975 • 150 citations

Transient kinetics of sarcoplasmic reticulum Ca2++Mg2+ ATPase studied by fluorescence

1978 • 144 citations

Reaction mechanism of calcium-ATPase of sarcoplasmic reticulum. Substrates for phosphorylation reaction and back reaction, and further resolution of phosphorylated intermediates.

1980 • 129 citations

Possible functional states of the enzyme of the sarcoplasmic calcium pump

1973 • 123 citations

Reaction Mechanism of the Ca++-Dependent ATPase of Sarcoplasmic Reticulum from Skeletal Muscle*

1968 • 116 citations

Reaction mechanism of Ca2+-dependent ATP hydrolysis by skeletal muscle sarcoplasmic reticulum in the absence of added alkali metal salts. II. Kinetic properties of the phosphoenzyme formed at the steady state in high Mg2+ and low Ca2+ concentrations.

1978 • 111 citations

Phosphorylation of solubilized sarcoplasmic reticulum by orthophosphate and its thermodynamic characteristics. The dominant role of entropy in the phosphorylation.

1975 • 108 citations

Reaction mechanism of Ca2+-dependent ATP hydrolysis by skeletal muscle sarcoplasmic reticulum in the absence of added alkali metal salts. III. Sequential occurrence of ADP-sensitive and ADP-insensitive phosphoenzymes.

1978 • 101 citations

Reaction mechanism of Ca2+-dependent ATP hydrolysis by skeletal muscle sarcoplasmic reticulum in the absence of added alkali metal salts. I. Characterization of steady state ATP hydrolysis and comparison with that in the presence of KCl.

1978 • 100 citations

Caclium uptake and associated adenosine triphosphatase activity in fragmented sarcoplasmic reticulum. Requirement for potassium ions.

1977 • 99 citations

A direct fluorescence study of the transient steps induced by calcium binding to sarcoplasmic reticulum ATPase.

1980 • 91 citations

Activation of calcium transport in skeletal muscle sarcoplasmic reticulum by monovalent cations.

1976 • 89 citations

On the mechanism of Ca2+-dependent adenosine triphosphatase of sarcoplasmic reticulum. Occurrence of two types of phosphoenzyme intermediates in the presence of KCl.

1979 • 79 citations

Behavior of the Ca2+ transport sites linked with the phosphorylation reaction of ATPase purified from the sarcoplasmic reticulum.

1976 • 77 citations

The Role of Calcium and Magnesium in the Adenosine Triphosphatase Reaction of Sarcoplasmic Reticulum

1971 • 76 citations

The interaction of magnesium ions with the calcium pump of sarcoplasmic reticulum

1976 • 61 citations

Sequential reactions in Pi utilization for ATP synthesis by sarcoplasmic reticulum.

1979 • 52 citations

Effect of K+ on phosphorylation of the sarcoplasmic reticulum ATPase by either Pi or ATP.

1980 • 44 citations

An estimate of the kinetics of calcium binding and dissociation of the sarcoplasmic reticulum transport ATPase

1978 • 40 citations

ADP-Sensitive and -Insensitive Phosphorylated Intermediates of Solubilized Ca2+, Mg2+-Dependent ATPase of the Sarcoplasmic Reticulum from Skeletal Muscle1

1979 • 35 citations

Transient state kinetic studies of phosphorylation by ATP and Pi of the calcium-dependent ATPase from sarcoplasmic reticulum

1979 • 28 citations

Sodium and Potassium Effects on Skeletal Muscle Microsomal Adenosine Triphosphatase and Calcium Uptake

1967 • 27 citations

The effect of lithium and potassium on the transient state kinetics of the (Ca + Mg)-ATPase of cardiac sarcoplasmic reticulum.

1978 • 26 citations

[44] Reconstitution of functional sarcoplasmic reticulum membrane vesicles

1974 • 25 citations

Reaction mechanism of (Ca2+, Mg2+)-ATPase of sarcoplasmic reticulum vesicles. I. Phosphoenzyme with bound Ca2+ which is exposed to the external medium.

1981 • 23 citations