The Biological Function of the Major Histocompatibility Complex: Hypotheses

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

Histocompatibility-Linked Immune Response Genes

1972 • 1,194 citations

Biology of the Mouse Histocompatibility-2 Complex

1975 • 1,145 citations

The somatic generation of immune recognition

1971 • 974 citations

The H-2 Major Histocompatibility Complex and the/Immune Response Region: Genetic Variation, Function, and Organization

1975 • 774 citations

Histocompatibility Testing 1965

1966 • 629 citations

A complete immunoglobulin gene is created by somatic recombination.

1978 • 610 citations

Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

1974 • 572 citations

Genetic Control Of Murine Viral Leukemogenesis

1973 • 452 citations

Induction of T and B cell immunity by anti‐idiotypic antibody

1975 • 448 citations

Specificity of Virus‐Immune Effector T Cells for H‐2K or H‐2D Compatible Interactions: Implications for H‐Antigen Diversity

1976 • 385 citations

Leukemogenic Activity of Filtrates from Radiation-Induced Lymphoid Tumors of Mice

1959 • 369 citations

GENETIC CONTROL OF THE IMMUNE RESPONSE

1972 • 355 citations

GENETIC BASIS OF SUSCEPTIBILITY TO VIRAL LEUKÆMOGENESIS

1964 • 350 citations

Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. I. Demonstration of similar or identical idiotypes on IgG molecules and T-cell receptors with specificity for the same alloantigens.

1975 • 347 citations

On the natural history of the murine leukemias: presidential address.

1967 • 330 citations

The β2-microglobulin gene is on chromosome 15 and not in the HL-A region

1975 • 274 citations

HLA restriction of cell-mediated lysis of influenza virus-infected human cells

1977 • 274 citations

THE GIX SYSTEM

1971 • 261 citations

Linkage of HL‐A and GBG¹

1974 • 242 citations

The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism.

1968 • 238 citations

Inherited structural polymorphism in human C2: evidence for genetic linkage between C2 and Bf.

1976 • 236 citations

Mutation Induction in Mice

1974 • 228 citations

Some Recent Work on Tumor Immunity

1956 • 225 citations

Enhanced expression of β ₂ -microglobulin and HLA antigens on human lymphoid cells by interferon

1978 • 215 citations

Human (HLA-A and HLA-B) and murine (H-2K and H-2D) histocompatibility antigens are cell surface receptors for Semliki Forest virus.

1978 • 210 citations

Histocompatibility antigens, immune responsiveness and susceptibility to disease

1972 • 210 citations

LEUKEMIA-ASSOCIATED TRANSPLANTATION ANTIGENS RELATED TO MURINE LEUKEMIA VIRUS

1973 • 199 citations

The Histocompatibility-Linked Immune Response Genes

1975 • 186 citations

TheTla region of the mouse: Identification of a new serologically defined locus,Qa-2

1976 • 168 citations

Contemporary topics in molecular immunology

1974 • 158 citations

A new serologically defined locus,Qa-1, in theTla-region of the mouse

1976 • 156 citations

THE EFFECT OF HISTOCOMPATIBILITY-2 TYPE ON RESPONSE TO THE FRIEND LEUKEMIA VIRUS IN MICE

1968 • 156 citations

Shared Idiotypic Determinants on B and T Lymphocytes Reactive Against the Same Antigenic Determinants

1976 • 152 citations

Induction of maturation in Xenopus laevis oocytes by a steroid linked to a polymer

1978 • 149 citations

Mating preferences of F2 segregants of crosses between MHC-congenic mouse strains

1978 • 149 citations

Biochemical properties and immunochemical-genetic relationships of mouse H-2 alloantigens

1974 • 143 citations

Further evidence for derepression of H–2 and Ia-like specificities of foreign haplotypes in mouse tumour cell lines

1976 • 138 citations

A sex-limited serum protein variant in the mouse: Inheritance and association with the H-2 region

1970 • 127 citations

H–2-like specificities of foreign haplotypes appearing on a mouse sarcoma after vaccinia virus infection

1976 • 123 citations

Immunochemical characterization of murine H-2 controlled Ss (serum substance) protein through identification of its human homologue as the fourth component of complement.

1975 • 120 citations

Occurrence of natural antibody to the G (gross) leukemia antigen in mice.

1966 • 116 citations

The Association Between Genes in the Major Histocompatibility Complex and Disease Susceptibility

1977 • 114 citations

Influenza virus‐specific cytotoxic T cells in man; induction and properties of the cytotoxic cell

1978 • 112 citations

T-lymphocyte response to Friend virus-induced tumour cell lines in mice of strains congenic at H–2

1976 • 106 citations

Increased synthesis and expression of H-2 antigens on thymocytes as a result of radiation leukemia virus infection: a possible mechanism for H-2 linked control of virus-induced neoplasia.

1978 • 95 citations

HLA restriction of human cytotoxic T lymphocytes specific for influenza virus. Poor recognition of virus associated with HLA A2.

1978 • 89 citations

INTERACTION OF HLA MOLECULES WITH NON-IMMUNOLOGICAL LIGANDS AS AN EXPLANATION OF HLA AND DISEASE ASSOCIATIONS

1976 • 87 citations

Evolution and Function of the Major Histocompatibility System: Facts and Speculations

1977 • 86 citations

Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses

1978 • 85 citations

Genetic Association between H-2 Gene and Testosterone Metabolism in Mice

1972 • 85 citations

Palatal cytosol cortisol-binding protein associated with cleft palate susceptibility and H–2 genotype

1977 • 84 citations

CORTISONE-INDUCED CLEFT PALATE IN THE MOUSE. A SEARCH FOR THE GENETIC CONTROL OF THE EMBRYONIC RESPONSE TRAIT

1977 • 82 citations

Identification of mouse chromosomes required for murine leukemia virus replication

1977 • 81 citations

Properdin factor B and histocompatibility loci linked in the rhesus monkey

1975 • 75 citations

Genetic nomenclature for theH-2 complex of the mouse

1974 • 70 citations

Mouse Leukæmias: Genetic Determination of the TL (Thymus–leukæmia) Antigen in the Mouse

1964 • 67 citations

A role for elevated H-2 antigen expression in resistance to neoplasia caused by radiation-induced leukemia virus. Enhancement of effective tumor surveillance by killer lymphocytes.

1979 • 67 citations

Assignment of the receptor for ecotropic murine leukemia virus to mouse chromosome 5.

1978 • 65 citations

Radiation leukemia in C57BL/6 mice. II. Lack of ecotropic virus expression in the majority of lymphomas.

1976 • 63 citations

Effect of the H-2 gene complex rates of fibroblast intercellular adhesion

1978 • 62 citations

Radiation leukemia in C57BL/6 mice. I. Lack of serological evidence for the role of endogenous ecotropic viruses in pathogenesis.

1976 • 58 citations

The Role of Genetics in Gross Virus Leukemogenesis1

2015 • 56 citations

Effect of Type I and Type II interferons on murine thymocyte surface antigen expression: Induction or selection?

1981 • 55 citations

Histocompatibility gene mutation rates: H-2 and non-H-2

1975 • 55 citations

The role of thymus subpopulations in “T” leukemia development

1976 • 54 citations

Association of mouse liver adenosine 3':5'-cyclic monophosphate (cyclic AMP) levels with histocompatibility-2 genotype.

1975 • 52 citations

Preliminary Amino Acid Sequences of Transplantation Antigens: Genetic and Evolutionary Implications

1976 • 52 citations

Shared Idiotypic Determinants on B and T Lymphocytes Reactive Against the Same Antigenic Determinants.

1975 • 51 citations

Mapping of anH-2-linked gene that influences mating preference in mice

1978 • 48 citations

Studies on Recombination within the Mouse H‐2 Complex I.: Three Recombinants Which Position the Ss Locus within the Complex

1972 • 43 citations

H‐2 AND NON ‐H‐2 DETERMINED STRAIN VARIATION IN PALATAL SHELF AND TONGUE ADENOSINE 3’:5’CYCLIC MONOPHOSPHATE: A POSSIBLE ROLE IN THE ETIOLOGY OF STEROID‐INDUCED CLEFT PALATE

1979 • 43 citations

CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES

1974 • 43 citations

CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES

1974 • 42 citations

BIOCHEMICAL POLYMORPHISM IN POPULATIONS OF THE HOUSE MOUSE AND OLD‐FIELD MOUSE

1970 • 41 citations

HERITABLE HISTOCOMPATIBILITY CHANGES

1966 • 40 citations

Spontaneous histocompatibility mutations detected by dermal grafts: Significant changes in rat over a 10-year period in the mouse H-system

1974 • 36 citations

A model for genetic analysis of programmed gene expression as reflected in the development of membrane antigens

1975 • 36 citations

Genetic differences in thymus, lymph node, testes and vesicular gland weights among inbred mouse strains. Association with the major histocompatibility (H-2) system.

1972 • 35 citations

Preleukemic expression of TL antigens in x-irradiated C57BL/6 mice.

1977 • 34 citations

Variations in viral gene expression in friend virus-transformed cell lines congenic with respect to the H-2 locus

1978 • 33 citations

Binding of HLA antigen-containing liposomes to bacteria

1978 • 32 citations

Sites of Localization and Synthesis of Ss Protein in Mice

1974 • 31 citations

The Specificity of T Lymphocyte Responses to Chemically Defined Antigens

1976 • 30 citations

In vivo or in vitro treatments with anti-I-J alloantisera abolish immunity to AKR leukemia.

1980 • 29 citations

Variation in mammalian populations

1973 • 29 citations

INTERCELLULAR ADHESIVENESS OF H‐2 IDENTICAL AND H‐2 DISPARATE CELLS

1978 • 22 citations

Multigene Family of Endogenous Retroviruses: Recombinant Origin of Diversity<xref ref-type="fn" rid="FN3">3</xref>

1978 • 21 citations

H-2-associated differences in androgen-influenced organ weights of a and C57BL/10 mouse strains and their crosses

1977 • 21 citations

Search for the physiological function of H‐2 gene products

1977 • 20 citations

Involvement of histocompatibility antigens in embryonic cell recognition events

1978 • 17 citations

Spontaneous frequencies of point mutations in mice

1972 • 16 citations

Recent studies on the role of the immune response in resistance to virus-induced leukemias and lymphomas.

1978 • 15 citations

Variation among inbred strains of mice in adenosine 3′:5′ cyclic monophosphate levels of spermatozoa

1979 • 13 citations

Preliminary studies on the topography of H-2d and mammary leukaemia (ML) antigens on DBA/2 mouse leukaemia cells.

1975 • 7 citations

H-2 associated genetic differences in androgen-dependent traits the effect of testosterone injections.

1973 • 5 citations

ANALYSIS OF GENETIC DIFFERENCES IN EARLY VERSUS LATE AGGLUTINABILITY WITH H‐2 ANTIBODIES OF NEONATAL MOUSE ERYTHROCYTES

1977 • 3 citations

Genetic differences in the levator ani muscle weight between inbred and congenic mouse strains.

1975 • 2 citations