Clinical update on the use of recombinant factor VII

The Effect of Activated Prothrombin-Complex Concentrate (FEIBA) on Joint and Muscle Bleeding in Patients with Hemophilia A and Antibodies to Factor VIII

1981 • 303 citations

Amino acid sequence and posttranslational modifications of human factor VIIa from plasma and transfected baby hamster kidney cells

1988 • 270 citations

Efficacy of Prothrombin-Complex Concentrates in Hemophiliacs with Antibodies to Factor VIII

1980 • 257 citations

Use of human factor VIIa in the treatment of two hemophilia A patients with high-titer inhibitors.

1983 • 239 citations

The Use of Porcine Factor VIII Concentrate (Hyate:C) in the Treatment of Patients With Inhibitor Antibodies to Factor VIII

1989 • 151 citations

Inhibition of factor VIIa/tissue factor-induced blood coagulation: with particular emphasis upon a factor Xa-dependent inhibitory mechanism

1989 • 141 citations

Efficacy and safety of vapor‐heated anti‐inhibitor coagulant complex in hemophilia patients. FEIBA Study Group

1990 • 131 citations

Factor VIIa in the treatment of haemophilia

1990 • 130 citations

Autoplex versus proplex: a controlled, double-blind study of effectiveness in acute hemarthroses in hemophiliacs with inhibitors to factor VIII

1983 • 125 citations

Effect of recombinant factor VIIa on the hemostatic defect in dogs with hemophilia A, hemophilia B, and von Willebrand disease.

1989 • 100 citations

Evidence for tissue factor-dependent activation of the classic extrinsic coagulation mechanism in blood obtained from bleeding time wounds

1988 • 99 citations

Mechanism by which recombinant factor VIIa shortens the aPTT: Activation of factor X in the absence of tissue factor

1989 • 76 citations

Hematologic Management of Hemophilia A for Surgery

1985 • 73 citations

Use of recombinant activated factor VII for treatment of a retropharyngeal hemorrhage in a hemophilic patient with a high titer inhibitor

1989 • 63 citations

Clinical Experience with Human Plasma-Derived Factor VIla in Patients with Hemophilia A and High Titer Inhibitors

1989 • 45 citations

Failure of Recombinant Activated Factor VII during Surgery in a Hemophiliac with High-Titer Factor VIII Antibody

1991 • 42 citations

Management of Hemophilia Patients with Inhibitors

1992 • 39 citations

Effect of natural killer cells on syngeneic bone marrow: in vitro and in vivo studies demonstrating graft failure due to NK cells in an identical twin treated by bone marrow transplantation

1985 • 31 citations

Surgery of hemophiliacs—20 years' experience

1977 • 31 citations

Comparison of the effect of plasma-derived and recombinant human FVIIa in vitro and in a rabbit model.

1990 • 22 citations

PROLONGED RECOMBINANT ACTIVATED FACTOR VII (rFVIIa) TREATMENT FOR SEVERE BLEEDING IN A FACTOR‐IX‐DEFICIENT PATIENT WITH AN INHIBITOR

1991 • 20 citations

The use of porcine factor VIII concentrate (Hyate:C) in the treatment of patients with inhibitor antibodies to factor VIII. A multicenter US experience

1989 • 15 citations

Hematologic management of hemophilia A for surgery

1985 • 12 citations

Experience With Recombinant Factor VIIA in an Infant Hemophiliac With Inhibitors to FVIILC Undergoing Emergency Central Line Placement

1993 • 11 citations

A therapeutic alternative for haemophiliacs with inhibitors

1992 • 5 citations

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