Interactions of alpha1-antitrypsin with trypsin and chymotrypsin.

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

1964 • 18,916 citations

Superoxide Dismutase

1969 • 12,578 citations

Ultraviolet Absorption Spectra of Proteins and Amino Acids

1952 • 1,094 citations

p-Nitrophenyl-p′-guanidinobenzoate HCl: A new active site titrant for trypsin

1967 • 848 citations

Sulfonyl Fluorides as Inhibitors of Esterases. I. Rates of Reaction with Acetylcholinesterase, α-Chymotrypsin, and Trypsin

1963 • 646 citations

Human leukocyte granule elastase: rapid isolation and characterization

1976 • 550 citations

The Determination of the Concentration of Hydrolytic Enzyme Solutions: α-Chymotrypsin, Trypsin, Papain, Elastase, Subtilisin, and Acetylcholinesterase¹

1966 • 386 citations

The Heterogeneity of Bovine Albumin with Respect to Sulfhydryl and Dimer Content

1968 • 379 citations

Ultra-Rapid Fluorescent Labelling of Proteins

1962 • 362 citations

A new convenient method for estimation of total cystine-cysteine in proteins

1969 • 346 citations

EVIDENCE FROM PHYSICAL CHEMISTRY REGARDING THE SIZE AND SHAPE OF PROTEIN MOLECULES FROM ULTRA‐CENTRIFUGATION, DIFFUSION, VISCOSITY, DIELECTRIC DISPERSION, AND DOUBLE REFRACTION OF FLOW

1941 • 295 citations

Selective removal of albumin from plasma by affinity chromatography

1973 • 293 citations

Isolation and properties of human plasma α-1-proteinase inhibitor

1974 • 263 citations

Inhibition of bovine factor IXa and factor Xa.beta. by antithrombin III

1976 • 161 citations

Purification and properties of normal human α1-antitrypsin

1973 • 126 citations

Measurement of Alpha1-Antitrypsin in Serum, by Immunodiffusion and by Enzymatic Assay

1974 • 108 citations

Human alpha-1-proteinase inhibitor mechanism of action: Evidence for activation by limited proteolysis

1976 • 103 citations

Proteinase Inhibitors of Human Plasma

1971 • 97 citations

Purification of alpha1-Antitrypsin from Plasma through Thiol-Disulfide Interchange

1975 • 96 citations

A Method for the Determination of Protein Partial Specific Volumes¹

1966 • 96 citations

Catalysis by chymotrypsinogen. Demonstration of an acyl-zymogen intermediate

1974 • 85 citations

Mechanism of interaction of bovine trypsin with human α1-antitrypsin

1974 • 72 citations

Conformation of the high pH form of chymotrypsin

1969 • 69 citations

Relation of the α-amino group of trypsin to enzyme function and zymogen activation

1973 • 64 citations

Gel filtration of proteins, with particular reference to the glycoprotein, luteinizing hormone

1965 • 63 citations

Pre‐existence of the active site in zymogens, the interaction of trypsinogen with the basic pancreatic trypsin inhibitor (Kunitz)

1976 • 57 citations

The purification of human serum α1-antitrypsin by affinity chromatography on concanavalin A

1973 • 55 citations

Mechanism of Action of α-1-Antitrypsin

1973 • 51 citations

Purification of human α₁‐antitrypsin by affinity chromatography on sepharose bound concanavalin A

1973 • 51 citations

Isolation and characterization of human plasma α 1-proteinase inhibitor and a conformational study of its interaction with proteinases

1976 • 47 citations

Catalysis by serine proteases and their zymogens. Study of acyl intermediates by circular dichroism

1975 • 40 citations

Isolation, chemical, and physical properties of α-1-antitrypsin

1976 • 40 citations

The interaction of α-1-antitrypsin with chymotrypsin, trypsin and elastase

1975 • 36 citations

Human serum α1-antitrypsin: Isolation and demonstration of electrophoretic and immunologic heterogeneity

1972 • 35 citations

Purification and chemical compositions of human α₁‐antitrypsin of the MM type

1973 • 34 citations

The Inhibition of Proteinases by Human α₁‐Antitrypsin

1974 • 31 citations

Large Scale Purification of Alpha-1 Trypsin Inhibitor from Human Plasma

1973 • 31 citations

The antithrombin activity of α-I-protease inhibitor: The antitrypsin activity of antithrombin III

1976 • 27 citations

The molecular stoichiometry of trypsin inhibition by human alpha-1-proteinase inhibitor

1974 • 26 citations

Isolation and Characterization of Alpha-1-Antitrrpsin from the Cohn Fraction Iv-1 of Human Plasma

1975 • 25 citations

Development of Large‐Scale Fractionation Methods

1972 • 19 citations

Purification of phenotypically unaltered α-1-antitrypsin

1974 • 13 citations

Association of Human α1-Antitrypsin with Anhydrotrypsin

1975 • 11 citations

Recovery of Protease Activities from Complexes with α-Antitrypsin

1973 • 10 citations

Resolution of plasma fraction IV components chromatography on DEAE-sephadex

1966 • 6 citations

Isolation of cu -Antitrypsin in a New Preparative Electrophoresis Apparatus

1975 • 3 citations