C-terminal region of adrenodoxin affects its structural integrity and determines differences in its electron transfer function to cytochrome P-450.

Molecular Cloning: A Laboratory Manual

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Molecular cloning: A laboratory manual

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1964 • 3,435 citations

High-level expression of sperm whale myoglobin in Escherichia coli.

1987 • 338 citations

A thermodynamic model of regulation: modulation of redox equilibria in camphor monoxygenase.

1976 • 261 citations

Components of the Electron Transport System in Adrenal Steroid Hydroxylase

1967 • 239 citations

Steroidogenic electron transport in adrenal cortex mitochondria

1982 • 191 citations

Ionic effects on adrenal steroidogenic electron transport. The role of adrenodoxin as an electron shuttle.

1979 • 167 citations

Studies on Adrenal Steroid Hydroxylases

1973 • 161 citations

Site-specific mutations in human ferredoxin that affect binding to ferredoxin reductase and cytochrome P450scc.

1991 • 160 citations

Identification by site-directed mutagenesis of two lysine residues in cholesterol side chain cleavage cytochrome P450 that are essential for adrenodoxin binding

1992 • 142 citations

Purification and immunochemical characterization of the two adrenal cortex mitochondrial cytochrome P-450-proteins

1978 • 136 citations

Mitochondrial cytochrome P-450sec. Mechanism of electron transport by adrenodoxin.

1980 • 120 citations

Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide.

1985 • 120 citations

The Amino Acid Sequence of Bovine Adrenodoxin

1973 • 119 citations

Adrenal steroid hydroxylases. Oxidation- reduction properties of adrenal iron-sulfur protein (adrenodoxin)

1973 • 107 citations

Adrenodoxin reductase.adrenodoxin complex. Flavin to iron-sulfur electron transfer as the rate-limiting step in the NADPH-cytochrome c reductase reaction.

1979 • 103 citations

Expression of bovine adrenodoxin in E. coli and site-directed mutagenesis of /2 FE2S/ cluster ligands

1992 • 101 citations

The formation of binary and ternary complexes of cytochrome P-450scc with adrenodoxin and adrenodoxin reductase.adrenodoxin complex. The implication in ACTH function.

1979 • 95 citations

Purification and properties of cytochrome P-45011β from adrenocortical mitochondria

1975 • 91 citations

Cytochrome P-450 for 11β- and 18-hydroxylase activities of bovine adrenocortical mitochondria: one enzyme or two?

1978 • 86 citations

Identification of specific carboxylate groups on adrenodoxin that are involved in the interaction with adrenodoxin reductase.

1984 • 84 citations

Phospholipid vesicle-reconstituted cytochrome P-450SCC. Mutually facilitated binding of cholesterol and adrenodoxin.

1980 • 84 citations

Discriminatory processing of the precursor forms of cytochrome P-450scc and adrenodoxin by adrenocortical and heart mitochondria.

1984 • 73 citations

The kinetics of reduction of cytochrome P-450cam by reduced putidaredoxin.

1981 • 70 citations

Cytochrome P-450scc-adrenodoxin complex. Reduction properties of the substrate-associated cytochrome and relation of the reduction states of heme and iron-sulfur centers to association of the proteins.

1983 • 66 citations

Mutations of tyrosine 82 in bovine adrenodoxin that affect binding to cytochromes P45011A1 and P45011B1 but not electron transfer.

1994 • 59 citations

Cytochrome P-450scc-adrenodoxin interactions. Ionic effects on binding, and regulation of cytochrome reduction by bound steroid substrates.

1985 • 57 citations

Mechanisms of ionic activation of adrenal mitochondrial cytochromes P-450scc and P-45011 beta.

1981 • 56 citations

The use of a specific fluorescence probe to study the interaction of adrenodoxin with adrenodoxin reductase and cytochrome P-450scc.

1987 • 52 citations

Molecular cloning and sequence analysis of human placental ferredoxin

1988 • 49 citations

Kinetics of O2 and CO Binding to adrenal cytochrome P-450scc. Effect of cholesterol, intermediates, and phosphatidylcholine vesicles.

1983 • 48 citations

[11] Expression of mammalian P450s in Escherichia coli

1991 • 47 citations

Sensitive assay of cytochrome P450scc activity by high-performance liquid chromatography

1989 • 41 citations

Heterogeneity of adrenocortical ferredoxin

1986 • 38 citations

Direct expression in Escherichia coli and characterization of bovine adrenodoxins with modified amino‐terminal regions

1992 • 35 citations

Partial Purification of a Metalloprotease Catalyzing the Processing of Adrenodoxin Precursor in Bovine Adrenal Cortex Mitochondria

1984 • 35 citations

The primary structure of bovine adrenodoxin

1970 • 34 citations

Identification of free and [Fe2S2]-bound cysteine residues of adrenodoxin.

1988 • 33 citations

Isolation and purification of mature bovine adrenocortical ferredoxin with an elongated carboxyl end

1988 • 30 citations

Purification and characterization of human placental ferredoxin

1988 • 29 citations

Kidney and adrenal mitochondria contain two forms of NADPH-adrenodoxin reductase-dependent iron-sulfur proteins. Isolation of the two porcine renal ferredoxins.

1986 • 28 citations

[12] Purification of adrenal cytochrome P-450 (cholesterol desmolase and steroid 11β- and 18-hydroxylase)

1978 • 28 citations

Active Complex between Adrenodoxin Reductase and Adrenodoxin in the Cytochrome P-450scc Reduction Reaction1

1989 • 27 citations

Proton nuclear magnetic resonance investigation of adrenodoxin

1991 • 26 citations

Adrenodoxin with a COOH-terminal Deletion (des 116–128) Exhibits Enhanced Activity

1989 • 26 citations

Cross-linking studies of adrenocortical cytochrome P-450scc. Evidence for a covalent complex with adrenodoxin and localization of the adrenodoxin-binding domain

1985 • 26 citations

Mature bovine adrenodoxin contains a 14-amino-acid COOH-terminal extension originally detected by cDNA sequencing

1987 • 24 citations

Cross-linking studies of the cholesterol hydroxylation system from bovine adrenocortical mitochondria

1989 • 17 citations

Electron paramagnetic resonance studies of the purified cytochrome P-450scc and P-45011β from bovine adrenocortical mitochondria

1979 • 10 citations