The effect of tobacco on lung cancer risk depends on CYP2D6 activity

IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans

1980 • 3,166 citations

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

1984 • 386 citations

A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin

1985 • 127 citations

Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity

1989 • 117 citations

Debrisoquine metabolism and genetic predisposition to lung cancer

1989 • 62 citations