Identification and characterization of a putative bile acid-responsive element in cholesterol 7 alpha-hydroxylase gene promoter

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Regulation of the mevalonate pathway

1990 • 5,282 citations

Current protocols in molecular biology

1988 • 4,543 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

1990 • 1,044 citations

The detection of DNA-binding proteins by protein blotting

1980 • 731 citations

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes.

1989 • 545 citations

The interplay of DNA-binding proteins on the promoter of the mouse albumin gene

1987 • 532 citations

Cholesterol 7α-hydroxylase

1977 • 504 citations

Regulation of the Apolipoprotein AI Gene by ARP-1, a Novel Member of the Steroid Receptor Superfamily

1991 • 382 citations

Cloning and regulation of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis.

1990 • 365 citations

Cell-type specific activity of two glucocorticoid responsive units of rat tyrosine aminotransferase gene is associated with multiple binding sites for C/EBP and a novel liver-specific nuclear factor

1991 • 234 citations

Characterization of drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene

1985 • 229 citations

HNF1, a homeoprotein member of the hepatic transcription regulatory network

1992 • 210 citations

Regulation of cholesterol 7 alpha-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 alpha-hydroxylase mRNA.

1990 • 208 citations

Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat

1991 • 194 citations

The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription.

1991 • 188 citations

Mechanisms of transactivation by retinoic acid receptors

1993 • 156 citations

Effect of thyroid hormone on hepatic cholesterol 7α hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats

1990 • 151 citations

Regulation of cholesterol 7 alpha-hydroxylase in the liver. Purification of cholesterol 7 alpha-hydroxylase and the immunochemical evidence for the induction of cholesterol 7 alpha-hydroxylase by cholestyramine and circadian rhythm.

1990 • 124 citations

Orphan receptor HNF-4 and bZip protein C/EBP alpha bind to overlapping regions of the apolipoprotein B gene promoter and synergistically activate transcription

1993 • 110 citations

Cloning of the human cholesterol 7α-hydroxylase gene (CYP7) and localization to chromosome 8q11–q12

1992 • 106 citations

Gene transcription; a practical approach

1993 • 82 citations

Transcriptional regulation of the human cholesterol 7.alpha.-hydroxylase gene

1992 • 72 citations

Hepatocyte nuclear factor-4 activates medium chain acyl-CoA dehydrogenase gene transcription by interacting with a complex regulatory element

1993 • 66 citations

Role of primary and secondary bile acids as feedback inhibitors of bile acid synthesis in the rat in vivo.

1989 • 64 citations

Structure of the rat gene encoding cholesterol 7.alpha.-hydroxylase

1990 • 61 citations

[46] Reversed-phase high-performance liquid chromatography assay of cholesterol 7α-hydroxylase

1991 • 56 citations

Genomic Cloning, Sequencing, and Analysis of the Hamster Cholesterol 7α-Hydroxylase Gene (CYP7)

1993 • 51 citations

Effects of Bile Acids and Steroid/Thyroid Hormones on the Expression of Cholesterol 7α-Hydroxylase mRNA and the CYP7 Gene in HepG2 Cells

1994 • 51 citations

Transcriptional regulation of the gene encoding cholesterol 7α-hydroxylase in the rat

1993 • 40 citations

Liver-specific factor binding to the liver promoter of a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene.

1993 • 39 citations

Similarities and differences in the function of regulatory elements at the 5' end of the human apolipoprotein B gene in cultured hepatoma (HepG2) and colon carcinoma (CaCo-2) cells.

1991 • 36 citations

Structure and Nucleotide Sequences of the Human Cholesterol 7α-Hydroxylase Gene (CYP7)

1994 • 35 citations

Cloning and 5′-flanking sequence of a rat cholesterol 7α-hydroxylase gene

1992 • 21 citations

Cholesterol 7α hydroxylase promoter separated from cyclophilin pseudogene by Alu sequence

1993 • 11 citations