Metabolism of leukotriene A4 by human erythrocytes. A novel cellular source of leukotriene B4.

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

The removal of leukocytes and platelets from whole blood.

1976 • 742 citations

Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica

1980 • 615 citations

Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds.

1979 • 556 citations

Mediation of local homeostasis and inflammation by leukotrienes and other mast cell-dependent compounds

1981 • 477 citations

Characterization and quantification of red cell lipids in normal man

1964 • 473 citations

Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids.

1979 • 465 citations

Synthesis of Prostacyclin from Platelet-derived Endoperoxides by Cultured Human Endothelial Cells

1980 • 385 citations

Formation of leukotrienes and other hydroxy acids during platelet-neutrophil interactions in vitro

1982 • 308 citations

Positional specificity of a reticulocyte lipoxygenase. Conversion of arachidonic acid to 15-S-hydroperoxy-eicosatetraenoic acid.

1982 • 202 citations

Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxy-icosatetraenoic acid.

1982 • 196 citations

Leukotriene a: Stereochemistry and enzymatic conversion to leukotriene B

1980 • 162 citations

Homolytic decomposition of linoleic acid hydroperoxide: Identification of fatty acid products

1974 • 156 citations

Decomposition of unsaturated fatty acid hydroperoxides by hemoglobin: Structures of major products of 13L‐hydroperoxy‐9,11‐octadecadienoic acid

1975 • 154 citations

Albumin stabilizes leukotriene A4.

1982 • 153 citations

Analysis of leukotrienes by high-pressure liquid chromatography

1981 • 119 citations

The use of prostacyclin in the separation from plasma and washing of human platelets

1982 • 115 citations

Isomers of leukotriene B4 possess different biological potencies

1981 • 93 citations

Studies on the mechanism of formation of the 5S,12S-dihydroxy-6,8,10,14(E,Z,E,Z)-icosatetraenoic acid in leukocytes

1982 • 84 citations

Leukotriene A4: Enzymatic conversion to leukotriene C4

1980 • 80 citations

Characterization of leukotriene A4 and B4 bioysnthesis

1983 • 70 citations

Metabolism of leukotriene A4 by an enzyme in blood plasma: a possible leukotactic mechanism.

1983 • 67 citations

Arachidonic acid metabolism by erythrocytes.

1983 • 54 citations

Mechanisms of leukotriene formation: Hemoglobin-catalyzed transformation of 15-HPETE into 8,15-diHETE and 14,15-diHETE isomers

1983 • 46 citations

Chemical studies on slow reacting substances/leukotrienes

1982 • 44 citations

Human erythrocyte membrane enzymes: current status and clinical correlates

1977 • 37 citations

A novel transformation of 13-ls-hydroperoxy-9, 11-octadecadienoicacid

1983 • 34 citations

Comparative effects of leukotriene B4, prostaglandins I2 and E2, 6-keto-PGF1α, thromboxane B2 and histamine on selected smooth muscle preparations

1981 • 32 citations

Structural requirement for the action of leukotriene B4 on the guinea-pig lung:Importance of double bond geometry in the 6, 8, 10-triene unit

1981 • 32 citations

Hemoprotein catalysis of leukotriene formation

1984 • 27 citations

Semi-preparative high-performance liquid chromatography and spectroscopic characterisation of eight geometric isomers of leukotriene A methyl ester

1981 • 12 citations