Molecular cloning of the mouse mast cell protease-5 gene. A novel secretory granule protease expressed early in the differentiation of serosal mast cells.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Serine Proteases: Structure and Mechanism of Catalysis

1977 • 1,238 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages

1990 • 481 citations

Native heparin from rat peritoneal mast cells.

1977 • 404 citations

Interleukin 3: A differentiation and growth factor for the mouse mast cell that contains chondroitin sulfate E proteoglycan.

1984 • 390 citations

Homologies in serine proteinases

1970 • 239 citations

Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases.

1990 • 210 citations

Cloning of the cDNA and gene of mouse mast cell protease-6. Transcription by progenitor mast cells and mast cells of the connective tissue subclass

1991 • 175 citations

GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene.

1991 • 162 citations

Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells.

1987 • 144 citations

Isolation and molecular cloning of mast cell carboxypeptidase A

1989 • 138 citations

Preparative purification of the rat mast cell chymase. Characterization and Interaction with granule components

1977 • 131 citations

Genomic Organization and Chromosomal Localization of the Human Cathepsin G Gene

1989 • 126 citations

Cloning of the mast cell protease, RMCP II. Evidence for cell-specific expression and a multi-gene family.

1987 • 122 citations

Identification and molecular cloning of a novel mouse mucosal mast cell serine protease.

1990 • 115 citations

The structure of rat mast cell protease II at 1.9-angstrom resolution

1988 • 112 citations

Cloning of the cDNA and gene for mouse mast cell protease 4. Demonstration of its late transcription in mast cell subclasses and analysis of its homology to subclass-specific neutral proteases of the mouse and rat

1991 • 112 citations

Complexes of heparin proteoglycans, chondroitin sulfate E proteoglycans, and [3H]diisopropyl fluorophosphate-binding proteins are exocytosed from activated mouse bone marrow-derived mast cells.

1986 • 106 citations

Amino acid sequence of rat mast cell protease I (chymase)

1987 • 96 citations

Carboxypeptidase A in mouse mast cells. Identification, characterization, and use as a differentiation marker.

1987 • 95 citations

Cytokine mRNA are preferentially increased relative to secretory granule protein mRNA in mouse bone marrow-derived mast cells that have undergone IgE-mediated activation and degranulation.

1991 • 89 citations

Rat peritoneal mast cell carboxypeptidase: localization, purification, and enzymatic properties

1980 • 80 citations

Low density lipoprotein degradation by secretory granules of rat mast cells. Sequential degradation of apolipoprotein B by granule chymase and carboxypeptidase A.

1986 • 80 citations

Amino acid sequence of a mouse mucosal mast cell protease

1989 • 77 citations

Immortalization of murine connective tissue-type mast cells at multiple stages of their differentiation by coculture of splenocytes with fibroblasts that produce Kirsten sarcoma virus.

1988 • 59 citations

Isolation and complete structure of the lymphocyte serine protease granzyme G, a novel member of the granzyme multigene family in murine cytolytic T lymphocytes. Evolutionary origin of lymphocyte proteases

1989 • 56 citations

Dog mast cell chymase: molecular cloning and characterization

1990 • 55 citations

Granule-associated serine neutral proteases of the mouse bone marrow-derived mast cell that degrade fibronectin: their increase after sodium butyrate treatment of the cells.

1984 • 47 citations

Rat mast cell carboxypeptidase: amino acid sequence and evidence of enzyme activity within mast cell granules

1991 • 41 citations

Organization of two genes encoding cytotoxic T lymphocyte-specific serine proteases CCPI and CCPII

1988 • 39 citations