Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1992 • 1,632 citations

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

1998 • 1,431 citations

Identification of a Protein That Purifies with the Scrapie Prion

1982 • 1,260 citations

Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples

1999 • 710 citations

Further purification and characterization of scrapie prions

1982 • 464 citations

Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells

1999 • 367 citations

Impaired Prion Replication in Spleens of Mice Lacking Functional Follicular Dendritic Cells

2000 • 354 citations

Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie

1996 • 333 citations

PrP protein is associated with follicular dendritic cells of spleens and lymph nodes in uninfected and scrapie‐infected mice

1992 • 224 citations

Complement Dependence of Localisation of Aggregated IgG in Germinal Centres

1975 • 210 citations

Post-mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy

1989 • 154 citations

Role of spleen macrophages in the clearance of scrapie agent early in pathogenesis

2000 • 145 citations

Potentiation of C1 inhibitor by glycosaminoglycans: dextran sulfate species are effective inhibitors of in vitro complement activation in plasma.

1997 • 129 citations

Tumor Necrosis Factor Alpha-Deficient, but Not Interleukin-6-Deficient, Mice Resist Peripheral Infection with Scrapie

2000 • 126 citations

Role of Complement in the Induction of Immunological Responses

1976 • 124 citations

Evidence for an Important Interaction Between a Complement-Derived CD21 Ligand on Follicular Dendritic Cells and CD21 on B Cells in the Initiation of IgG Responses

1998 • 117 citations

The complement system and adaptive immunity

1998 • 109 citations

Genetical control of the concentration of ME7 scrapie agent in the brain of mice

1969 • 105 citations

The role of complement in the acquired immune response

2000 • 103 citations

T Cell–dependent Immune Response in C1q-deficient Mice: Defective Interferon γ Production by Antigen-specific T Cells

1998 • 95 citations

C1q and C4b Bind Simultaneously to CR1 and Additively Support Erythrocyte Adhesion

1999 • 83 citations

A Targeted Disruption of the Murine Complement Factor B Gene Resulting in Loss of Expression of Three Genes in Close Proximity, Factor B, C2, and D17H6S45

1998 • 66 citations

Effect of Sinc genotype, agent isolate and route of infection on the accumulation of protease-resistant PrP in non-central nervous system tissues during the development of murine scrapie

1994 • 61 citations

Selective inhibition of immune complex trapping by follicular dendritic cells with monoclonal antibodies against rat C3

1992 • 51 citations

Isolation and study of murine C3.

1977 • 33 citations

An improved method for the isolation from Naja naja venom of cobra factor (CoF) free of phospholipase A

1979 • 32 citations

Cloning of the mouse homolog of the 126-kDa human C1q/MBL/SP-A receptor, C1qR p

1999 • 20 citations