Oxidation of Bromide by the Human Leukocyte Enzymes Myeloperoxidase and Eosinophil Peroxidase

Studies on the chlorinating activity of myeloperoxidase.

1976 • 918 citations

Chlorination of endogenous amines by isolated neutrophils. Ammonia-dependent bactericidal, cytotoxic, and cytolytic activities of the chloramines.

1984 • 397 citations

Brominating Oxidants Generated by Human Eosinophils

1986 • 364 citations

[40] Preparation and characterization of chloramines

1986 • 345 citations

Assessment of chlorination by human neutrophils

1983 • 285 citations

Myeloperoxidase-dependent effect of amines on functions of isolated neutrophils.

1983 • 257 citations

Myeloperoxidase, hydrogen peroxide, chloride antimicrobial system: nitrogen-chlorine derivatives of bacterial components in bactericidal action against Escherichia coli

1979 • 251 citations

Accumulation of Hypothiocyanite Ion during Peroxidase‐Catalyzed Oxidation of Thiocyanate Ion

1977 • 249 citations

Singlet oxygen production by human eosinophils.

1988 • 207 citations

The reductive cleavage of myeloperoxidase in half, producing enzymically active hemi-myeloperoxidase.

1981 • 196 citations

Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs

1991 • 187 citations

Human eosinophil peroxidase: purification and characterization.

1985 • 174 citations

Assay of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase

1990 • 169 citations

Myeloperoxidase-Hydrogen Peroxide-Chloride Antimicrobial System: Effect of Exogenous Amines on Antibacterial Action Against Escherichia coli

1979 • 168 citations

Taurine and Hypotaurine Content of Human Leukocytes

1990 • 153 citations

Tumor necrosis factor alpha/cachectin stimulates eosinophil oxidant production and toxicity towards human endothelium.

1990 • 148 citations

Eosinophils Preferentially Use Bromide to Generate Halogenating Agents

1989 • 148 citations

Singlet oxygen production by lactoperoxidase.

1983 • 144 citations

Bactericidal activity of eosinophil peroxidase.

1980 • 144 citations

Thiocyanate is the major substrate for eosinophil peroxidase in physiologic fluids. Implications for cytotoxicity.

1991 • 129 citations

Oxidation of chloride and thiocyanate by isolated leukocytes.

1986 • 129 citations

Some properties of human eosinophil peroxidase, a comparison with other peroxidases

1984 • 124 citations

Singlet oxygen production by chloroperoxidase-hydrogen peroxide-halide systems.

1984 • 117 citations

Evidence for a role of taurine in the in vitro oxidative toxicity of neutrophils toward erythrocytes.

1985 • 116 citations

Biochemical requirements for singlet oxygen production by purified human myeloperoxidase.

1984 • 113 citations

The generation of utilization of chlorinated oxidants by human neutrophils

1986 • 110 citations

Rates of formation of N-bromo amines in aqueous solution

1982 • 103 citations

Myeloperoxidase-dependent fluorescein chlorination by stimulated neutrophils.

1984 • 100 citations

Inhibition of the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase by dapsone

1992 • 100 citations

Direct potentiometric determination of chloride ion in whole blood

1981 • 79 citations

Chemistry and biochemistry of thiocyanic acid and its derivatives

1976 • 61 citations

Arming of mononuclear phagocytes by eosinophil peroxidase bound to Staphylococcus aureus.

1982 • 59 citations

Mutagenic activity of chloramines

1987 • 59 citations

Studies on Myeloperoxidase Activity. I. Spectrophotometry of the MPO-H2O2 Compound.

1963 • 54 citations

The rapid determination of total bromine and iodine in biological fluids by neutron activation

1980 • 53 citations

Spectral properties of myeloperoxidase Compounds II and III

1987 • 51 citations

Characterization of bromine-77-labeled proteins prepared using bromoperoxidase.

1980 • 37 citations

Bromine derivatives of amino acids as intermediates in the peroxidase-catalyzed formation of singlet oxygen

1989 • 37 citations

Sites of direct and indirect halogenation of albumin

1978 • 30 citations

Protein bromination by bromoperoxidase from Penicillus capitatus

1984 • 17 citations

Evidence that eosinophils catalyze the bromide-dependent decarboxylation of amino acids

1981 • 16 citations

Investigations into lactoperoxidase-catalysed bromination of tyrosine and thyroglobulin

1988 • 12 citations

Oxidations of the carcinogen N-hydroxy-N-(2-fluorenyl)acetamide by enzymically or chemically generated oxidants of chloride and bromide

1989 • 11 citations