Polymer-protomer transition of acetyl-CoA carboxylase occurs in vivo and varies with nutritional conditions.
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Abstract
References (28)
Fatty acid synthesis in adipose tissue incubated in tritiated water
1968 • 390 citations
Variations in tissue contents of coenzyme A thio esters and possible metabolic implications
1964 • 343 citations
Acetyl Coenzyme A Carboxylase
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Acetyl coenzyme A carboxylase.
1974 • 216 citations
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1975 • 196 citations
Regulation of the Activity of Acetyl Coenzyme A Carboxylase by Palmitoyl Coenzyme A and Citrate
1972 • 195 citations
The Concentration of Malonyl-Coenzyme A and the Control of Fatty Acid Synthesis in Vivo
1972 • 182 citations
Acetyl Coenzyme A Carboxylase* *The investigations cited in this review and unpublished studies carried out in the authors' laboratory were supported in part by research grants AM-14574 and AM-14575, United States Public Health Service and a research grant from the American Heart Association, Inc.
1974 • 136 citations
Molecular characteristics of liver acetyl CoA carboxylase.
1966 • 134 citations
Hormonal regulation of adipose-tissue acetyl-coenzyme A carboxylase by changes in the polymeric state of the enzyme. The role of long-chain fatty acyl-coenzyme A thioesters and citrate
1974 • 104 citations
Glucagon regulation of protein phosphorylation. Identification of acetyl coenzyme A carboxylase as a substrate.
1979 • 104 citations
Effect of glucagon on hepatic malonyl coenzyme A concentration and on lipid synthesis.
1977 • 99 citations
LIVER ACETYL COA CARBOXYLASE: THE DISSOCIATION-REASSOCIATION PROCESS AND ITS RELATION TO CATALYTIC ACTIVITY
1966 • 89 citations
Acetyl-CoA carboxylase. Evidence for polymeric filament to protomer transition in the intact avian liver cell.
1978 • 85 citations
Mechanism for acute control of fatty acid synthesis by glucagon and 3':5'-cyclic AMP in the liver cell.
1977 • 84 citations
Inhibitory effects of long‐chain acyl coenzyme a analogues on rat liver acetyl coenzyme a carboxylase
1979 • 78 citations
Hepatic Fatty Acid Synthesis and Plasma Free Fatty Acid Levels in Chicks Subjected to Short Periods of Food Restriction and Refeeding
1970 • 65 citations
Acetyl Coenzyme A Carboxylase
1972 • 64 citations
Liver acetyl CoA carboxylase: insight into the mechanism of activation by tricarboxylic acids and acetyl CoA.
1967 • 64 citations
Regulation of rat liver acetyl-CoA carboxylase. Stimulation of phosphorylation and subsequent inactivation of liver acetyl-CoA carboxylase by cyclic 3‘:5‘-monophosphate and effect on the structure of the enzyme.
1978 • 56 citations
Studies on the Relationship between Lipogenesis and the Level of Coenzyme a Derivatives, Lactate and Pyruvate in Chick Liver
1971 • 54 citations
Acetyl coenzyme A carboxylase. Purification and properties of the bovine adipose tissue enzyme
1972 • 51 citations
Acute control of fatty acid synthesis by cyclic AMP in the chick liver cell: possible site of inhibition of citrate formation.
1979 • 47 citations
Fatty acid biosynthesis in Erlich cells. The mechanism of short term control by exogenous free fatty acids.
1975 • 43 citations
Regulation of Fatty Acid Synthesis in the Liver of Prenatal and Early Postnatal Chicks
1973 • 42 citations
Heat activation of rat liver acetyl-CoA carboxylase in vitro.
1978 • 41 citations
Essentiality of Dietary Carbohydrate for Maintenance of Liver Lipogenesis in the Chick
1980 • 32 citations
In Vivo Effects of Glucagon on Fatty Acid Synthesis in Fasted and Refed Rats
1977 • 17 citations