Differential phosphorylation of the progesterone receptor by insulin, epidermal growth factor, and platelet-derived growth factor receptor tyrosine protein kinases.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The Determination of Enzyme Dissociation Constants

1934 • 11,865 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells

1984 • 1,416 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Nuclear localization of unoccupied oestrogen receptors

1984 • 882 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.

1977 • 844 citations

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.

1984 • 715 citations

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1982 • 680 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Vinculin: A cytoskeletal target of the transforming protein of rous sarcoma virus

1981 • 591 citations

Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus

1980 • 560 citations

Phosphorylation activates the insulin receptor tyrosine protein kinase.

1983 • 558 citations

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

1979 • 517 citations

Specific and Nonspecific Physicochemical Interactions of Glucocorticoids and Related Steroids with Rat Thymus Cells in Vitro

1968 • 381 citations

Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins

1982 • 366 citations

Isolation of a calcium-dependent 35-kilodalton substrate for the epidermal growth factor receptor/kinase from A-431 cells.

1984 • 366 citations

Molybdate inhibition of glucocorticoid receptor inactivation and transformation.

1979 • 339 citations

Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.

1984 • 331 citations

Tyrosine-specific protein kinase activity is associated with the purified insulin receptor.

1983 • 324 citations

Molecular Biology of the Human T-Lymphotropic Retroviruses

1986 • 324 citations

Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity.

1984 • 299 citations

Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes.

1982 • 293 citations

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.

1983 • 291 citations

Variants of 3T3 cells lacking mitogenic response to epidermal growth factor.

1977 • 280 citations

Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells.

1984 • 260 citations

Inhibition of progesterone receptor activation by sodium molybdate

1980 • 257 citations

Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I

1983 • 254 citations

Characterization of a tyrosine-specific kinase activity in human fibroblast membranes stimulated by platelet-derived growth factor.

1982 • 253 citations

Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus

1983 • 225 citations

Androgen Receptor Assay with [³H]Methyltrienolone (R1881) in the Presence of Progesterone Receptors*

1979 • 223 citations

Characterization of insulin-mediated phosphorylation of the insulin receptor in a cell-free system.

1983 • 223 citations

Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

1984 • 219 citations

Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta.

1984 • 201 citations

Direct demonstration of glucocorticoid receptor phosphorylation by intact L-cells.

1983 • 200 citations

Glucocorticoid receptor inactivation under cell-free conditions.

1977 • 196 citations

Characterization of the insulin receptor kinase purified from human placental membranes.

1983 • 196 citations

Progesterone-binding Protein of Chick Oviduct

1972 • 173 citations

Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes.

1982 • 166 citations

Dexamethasone modulates binding and action of epidermal growth factor in serum-free cell culture

1978 • 156 citations

DNA sequence preference of the progesterone receptor.

1983 • 150 citations

Characterization of platelet-derived growth factor-stimulated phosphorylation in cell membranes.

1983 • 147 citations

The Subunit Structure of Human Breast Cancer Progesterone Receptors: Characterization by Chromatography and Photoaffinity Labeling*

1983 • 142 citations

The rabbit progesterone receptor. Evidence for a single steroid-binding subunit and characterization of receptor mRNA.

1984 • 140 citations

ATP-dependent activation of L cell glucocorticoid receptors to the steroid binding form.

1979 • 140 citations

Evidence that viral transforming gene products and epidermal growth factor stimulate phosphorylation of the same cellular protein with similar specificity.

1981 • 137 citations

A comparison of the insulin- and epidermal growth factor-stimulated protein kinases from human placenta.

1984 • 137 citations

The kinetics of tyrosine phosphorylation by the purified epidermal growth factor receptor kinase of A-431 cells.

1983 • 124 citations

Inhibition of uterine estrogen receptor transformation by sodium molybdate.

1980 • 121 citations

Purification and characterization of the chick oviduct progesterone receptor a subunit

1979 • 113 citations

Phosphorylation of hen progesterone receptor by cAMP dependent protein kinase

1981 • 112 citations

Inactivation of glucocorticoid-binding capacity by protein phosphatases in the presence of molybdate and complete reactivation of dithiothreitol.

1982 • 106 citations

Inhibition of Insulin Receptor Binding by Phorbol Esters

1982 • 105 citations

Purification of "nontransformed" avian progesterone receptor and preliminary characterization.

1982 • 90 citations

Insulin-stimulated tyrosine protein kinase. Characterization and relation to the insulin receptor.

1984 • 85 citations

Glucocorticoid receptor activation and inactivation in cultured human lymphocytes.

1981 • 83 citations

Dual effects of the progestin R5020 on proteins released by the T47D human breast cancer cells.

1984 • 75 citations

Characteristics of Insulin and Epidermal Growth Factor Stimulation of Receptor Autophosphorylation in Detergent Extracts of Rat Liver and Transplantable Rat Hepatomas*

1984 • 72 citations

Insulin-stimulated tyrosine protein kinase. Characterization and relation to the insulin receptor.

1984 • 67 citations

Regulation of insulin receptor kinase activity by insulin mimickers and an insulin antagonist

1983 • 64 citations

Activation of glucocorticoid receptor by ATP

1979 • 59 citations

Preferential degradation of the beta subunit of purified insulin receptor. Effect on insulin binding and protein kinase activities of the receptor.

1983 • 56 citations

Progesterone receptors in human breast cancer. Stoichiometric translocation and nuclear receptor processing.

1983 • 55 citations

Progesterone Binding to Hen Oviduct Genome: Specific Versus Nonspecific Binding

1976 • 48 citations

Progesterone receptor subunits are high-affinity substrates for phosphorylation by epidermal growth factor receptor.

1984 • 44 citations

Epidermal growth factor and epidermal growth factor receptor-dependent phosphorylation of a Mr = 34,000 protein substrate for pp60src.

1983 • 36 citations