The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase

Automatic Recording Apparatus for Use in Chromatography of Amino Acids

1958 • 9,612 citations

A gas-liquid solid phase peptide and protein sequenator.

1981 • 2,238 citations

THE OXIDATION OF RIBONUCLEASE WITH PERFORMIC ACID

1956 • 1,868 citations

Structure of human pancreatic lipase

1990 • 1,203 citations

Contributions of mass spectrometry to peptide and protein structure

1988 • 992 citations

Inhibition of pancreatic lipase in vitro by the covalent inhibitor tetrahydrolipstatin

1988 • 338 citations

Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity.

1987 • 328 citations

Mode of action of tetrahydrolipstatin: a derivative of the naturally occurring lipase inhibitor lipstatin

1988 • 254 citations

Porcine pancreatic lipase. Completion of the primary structure

1981 • 159 citations

Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. II. Chemistry and structure elucidation.

1987 • 142 citations

Microscale isocratic separation of phenylthiohydantoin amino acid derivatives

1985 • 110 citations

Syntheses of Tetrahydrolipstatin and Absolute Configuration of Tetrahydrolipstatin and Lipstatin

1987 • 90 citations

Characterization of the serine reacting with diethyl p-nitrophenyl phosphate in porcine pancreatic lipase

1981 • 89 citations

Minireview on pancreatic lipase and colipase

1988 • 89 citations

Mechanism of pancreatic lipase action. 2. Catalytic properties of modified lipases

1976 • 86 citations

Charge-remote fragmentations of closed-shell ions. A thermolytic analogy

1989 • 85 citations

Studies on the antiobesity activity of tetrahydrolipstatin, a potent and selective inhibitor of pancreatic lipase.

1987 • 79 citations

The Complete Amino Acid Sequences of Both Subunits of the Sweet Protein Monellin

1976 • 76 citations

Methods in protein sequence analysis

1988 • 63 citations

Hydrolysis of p‐nitrophenyl acetate by the peptide chain fragment (336–449) of porcine pancreatic lipase

1986 • 50 citations

Tetrahydrolipstatin: Thermal and Hydrolytic Degradation

1990 • 21 citations

Which class of serine is involved in the lipase mechanism?

1986 • 20 citations

Charge participation in the fragmentation of functionalized steroids

1970 • 16 citations

STRUCTURAL CHARACTERISTICS OF ENDOGENOUS SUGAR ACIDS AND RELATED FEEDING MODULATION

1987 • 5 citations