Multiple Forms of TGF‐β: Distinct Promoters and Differential Expression

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

The Transforming Growth Factor-βs

1990 • 741 citations

Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur.

1990 • 734 citations

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.

1990 • 647 citations

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

1988 • 604 citations

The tat Gene of Human T-Lymphotropic Virus Type 1 Induces Mesenchymal Tumors in Transgenic Mice

1987 • 522 citations

Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation.

1988 • 483 citations

Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye.

1989 • 481 citations

Immunodetection and quantitation of the two forms of transforming growth factor‐beta (TGF‐β1 and TGF‐β2) secreted by cells in culture

1989 • 453 citations

In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis.

1989 • 420 citations

Characterization of the Promoter Region of the Human Transforming Growth Factor-β1 Gene

1989 • 400 citations

Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action

1988 • 347 citations

Transforming growth factor-β in human aqueous humor

1990 • 337 citations

Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis.

1989 • 333 citations

In situ hybridization analysis of TGFβ3 RNA expression during mouse development: comparative studies with TGFβ1 and β2

1990 • 325 citations

Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts

1990 • 324 citations

An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes

1989 • 305 citations

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

1990 • 277 citations

Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis

1988 • 275 citations

Differential expression of TGF beta isoforms in murine palatogenesis

1990 • 257 citations

Promoter Sequences of the Human Transforming Growth Factor-β1 Gene Responsive to Transforming Growth Factor-β1 Autoinduction

1989 • 254 citations

Transforming growth factor-beta in the regulation of fracture repair.

1990 • 239 citations

Transforming Growth Factor Beta-1 in Acute Myocardial Infarction in Rats

1988 • 232 citations

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia.

1990 • 229 citations

Transforming growth factor-beta. Multiple actions and potential clinical applications

1989 • 229 citations

Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2.

1989 • 221 citations

Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation.

1989 • 213 citations

Transforming Growth Factor-β in the Regulation of Fracture Repair

1990 • 206 citations

Expression of transforming growth factor β2 RNA during murine embryogenesis

1989 • 202 citations

Differential expression of genes encoding TGFs β1, β2, and β3 during murine palate formation

1990 • 195 citations

Comparison of the biological actions of TGF beta‐1 and TGF beta‐2: Differential activity in endothelial cells

1988 • 195 citations

Transactivation of interleukin 2 and its receptor induces immune activation in human T-cell lymphotropic virus type I-associated myelopathy: pathogenic implications and a rationale for immunotherapy.

1990 • 194 citations

Activation of the second promoter of the transforming growth factor-β1 gene by transforming growth factor-β1 and phorbol ester occurs through the same target sequences

1989 • 185 citations

Differential inhibition of transforming growth factor beta 1 and beta 2 activity by alpha 2-macroglobulin.

1990 • 148 citations

Transforming Growth Factor—β

1989 • 148 citations

Expression of TGF-β isoforms during first trimester human embryogenesis

1990 • 139 citations

Structural and functional characterization of the transforming growth factor beta 3 promoter. A cAMP-responsive element regulates basal and induced transcription.

1990 • 124 citations

Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor.

1990 • 91 citations

trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene.

1989 • 80 citations

Mesoderm Induction in Xenopus laevis Distinguishes Between the Various TGF-β Isoforms

1990 • 65 citations

Alpha 2-macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-beta 2 in rat hepatocytes.

1990 • 64 citations

The Role of TGFβ in Mouse Development^a

1990 • 45 citations

Overexpression of transforming growth factor-beta in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene.

1991 • 38 citations