The binding of cyclosporin A to human plasma: an in vitro microdialysis study.

Microdialysis—principles and applications for studies in animals and man

1991 • 811 citations

Nephrotoxicity of Cyclosporin a after Allogeneic Marrow Transplantation

1981 • 364 citations

Role of lipoproteins and erythrocytes in the in vitro binding and distribution of cyclosporin A in the blood

1982 • 271 citations

Intracerebral microdialysis: I. Experimental studies of diffusion kinetics

1989 • 218 citations

Microdialysis calibration using retrodialysis and zero-net flux: application to a study of the distribution of zidovudine to rabbit cerebrospinal fluid and thalamus.

1993 • 175 citations

Intracerebral microdialysis: II. mathematical studies of diffusion kinetics

1989 • 158 citations

Factors Influencing the Pharmacokinetics of Cyclosporine in Man

1991 • 152 citations

CYCLOSPORINE-ASSOCIATED CENTRAL NERVOUS SYSTEM TOXICITY AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION

1984 • 114 citations

Microdialysis sampling for determination of plasma protein binding of drugs.

1990 • 95 citations

Cyclosporin: measurement of fraction unbound in plasma

1987 • 68 citations

BLOOD CYCLOSPORINE PHARMACOKINETICS IN PATIENTS UNDERGOING MARROW TRANSPLANTATION INFLUENCE OF AGE, OBESITY, AND HEMATOCRIT

1988 • 62 citations

Long-term cyclosporine pharmacokinetic changes in renal transplant recipients: Effects of binding and metabolism

1989 • 59 citations

Potential use of microdialysis in pharmacokinetics: a protein binding study.

1992 • 50 citations

Saturable binding of cyclosporin A to erythrocytes: estimation of binding parameters in renal transplant patients and implications for bioavailability assessment.

1988 • 33 citations

Impact of lipoproteins on cyclosporine pharmacokinetics and biological activity in transplant patients.

1990 • 29 citations

THE ROLE OF CYCLOSPORINE DOSAGE AND PLASMA LEVELS IN EFFICACY AND TOXICITY IN BONE MARROW TRANSPLANT RECIPIENTS

1987 • 27 citations

Intra- and Interindividual Variability in the Free Fraction of Cyclosporine in Plasma in Recipients of Renal Transplants

1989 • 25 citations

A new method for measuring the free fraction of cyclosporin in plasma by equilibrium dialysis

1987 • 25 citations

The pharmacokinetics of cyclosporine. II. Blood plasma distribution and binding studies.

1985 • 24 citations

Blood Protein Binding of Cyclosporine in Transplant Patients

1987 • 24 citations

A Model to Account for the Variation in Cyclosporin Binding to Plasma Lipids in Transplant Patients

1988 • 20 citations

Cyclesporin

1988 • 19 citations

Pharmacokinetic and pharmacodynamic studies of cyclosporine in bone marrow transplantation.

1990 • 16 citations

The estimation of the plasma free fraction of cyclosporine in rabbits and heart transplant patients: The application of a physiological model of renal clearance

1995 • 2 citations