Molecular Biology of Cellular Membranes with Applications to Immunology

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

Proteins, amino acids and peptides

1943 • 2,189 citations

Rhodopsin-like Protein from the Purple Membrane of Halobacterium halobium

1971 • 2,075 citations

Microfilaments in Cellular and Developmental Processes

1971 • 1,563 citations

An enzymic method for the trace iodination of immunoglobulins and other proteins

1969 • 1,414 citations

Histocompatibility-Linked Immune Response Genes

1972 • 1,194 citations

Effects of Cytochalasins on Mammalian Cells

1967 • 947 citations

Inside-outside transitions of phospholipids in vesicle membranes

1971 • 942 citations

The rapid intermixing of cell surface antigens after formation of mouse human heterokaryons

1970 • 861 citations

Metabolic dependence of red cell deformability

1969 • 830 citations

Subcellular Particles

1959 • 799 citations

Fracture faces of frozen membranes.

1966 • 745 citations

Rotational Diffusion of Rhodopsin in the Visual Receptor Membrane

1972 • 683 citations

ELECTRON MICROSCOPE OBSERVATIONS ON THE CARBOHYDRATE-RICH CELL COAT PRESENT AT THE SURFACE OF CELLS IN THE RAT

1967 • 660 citations

The Regulatory Influence of Activated T Cells on B Cell Responses to Antigen

1972 • 633 citations

Protein-Protein Interactions

1954 • 574 citations

MEMBRANE SPLITTING IN FREEZE-ETCHING

1970 • 573 citations

A DIFFERENCE IN THE ARCHITECTURE OF THE SURFACE MEMBRANE OF NORMAL AND VIRALLY TRANSFORMED CELLS

1969 • 549 citations

The concept of carrier transport and its corollaries in pharmacology.

1961 • 541 citations

INTERACTION OF THE CARBOHYDRATE-BINDING PROTEIN CONCANAVALIN A WITH NORMAL AND TRANSFORMED CELLS

1969 • 525 citations

The Regulatory Role of Macrophages in Antigenic Stimulation

1972 • 506 citations

The Low Polarity of Many Membrane Proteins

1972 • 498 citations

Human Monocytes: Distinct Receptor Sites for the Third Component of Complement and for Immunoglobulin G

1968 • 492 citations

PROPERTIES OF ANTIBODIES CYTOPHILIC FOR MACROPHAGES

1966 • 487 citations

The role of alpha-lactalbumin and the A protein in lactose synthetase: a unique mechanism for the control of a biological reaction.

1968 • 459 citations

A Form of Cytochrome b ₅ That Contains an Additional Hydrophobic Sequence of 40 Amino Acid Residues

1971 • 453 citations

The dynamic state of the lymphocyte membrane. Factors affecting the distribution and turnover of surface immunoglobulins

1972 • 450 citations

Localization of red cell membrane constituents

1973 • 431 citations

Structure and Function in Biological Membranes

1965 • 427 citations

PERMEABILITY OF NATURAL MEMBRANES

1953 • 421 citations

Selective Solubilization of a Protein Component of the Red Cell Membrane

1968 • 416 citations

SOME ASPECTS OF NORMAL AND ABNORMAL CELL SURFACE GENETICS

1969 • 415 citations

Aeronautics before 1919

1971 • 413 citations

Glycoproteins

1970 • 408 citations

Chemical Characterization and Surface Orientation of the Major Glycoprotein of the Human Erythrocyte Membrane

1972 • 401 citations

CALORIMETRIC EVIDENCE FOR THE LIQUID-CRYSTALLINE STATE OF LIPIDS IN A BIOMEMBRANE

1969 • 386 citations

Structure and Function of Biological Membranes

1971 • 384 citations

CELL SURFACE IMMUNOGLOBULIN

1971 • 380 citations

REGULATION OF ENZYME FUNCTION

1969 • 374 citations

Hydrogen Bonds between Model Peptide Groups in Solution

1962 • 370 citations

The Binding of Detergents to Lipophilic and Hydrophilic Proteins

1972 • 357 citations

INTESTINAL TRANSPORT OF ANTIBODIES IN THE NEWBORN RAT

1973 • 349 citations

Receptor Sites of Human Monocytes for IgG

1968 • 349 citations

LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECULES

1972 • 349 citations

The arrangement of proteins in the human erythrocyte membrane

1970 • 342 citations

Transport of Amino Acids by Confluent and Nonconfluent 3T3 and Polyoma Virus-transformed 3T3 Cells Growing on Glass Cover Slips

1969 • 335 citations

TRANSLATIONAL MOBILITY OF THE MEMBRANE INTERCALATED PARTICLES OF HUMAN ERYTHROCYTE GHOSTS

1972 • 325 citations

A major protein which spans the human erythrocyte membrane

1971 • 322 citations

ANTIGENIC MODULATION

1968 • 322 citations

Disposition of the major proteins in the isolated erythrocyte membrane. Proteolytic dissection

1971 • 321 citations

Membrane Proteins

1972 • 321 citations

PROTEIN CONFORMATION IN CELL MEMBRANE PREPARATIONS AS STUDIED BY OPTICAL ROTATORY DISPERSION AND CIRCULAR DICHROISM

1966 • 320 citations

Cyclic adenosine 3′,5′-monophosphate in human lymphocytes. Alterations after phytohemagglutinin stimulation

1971 • 310 citations

ANIONIC SITES OF HUMAN ERYTHROCYTE MEMBRANES

1973 • 307 citations

Phosphatidyl-ethanolamine: Differential labelling in intact cells and cell ghosts of human erythrocytes by a membrane-impermeable reagent

1972 • 287 citations

The Binding of Cytochrome b5 to Liver Microsomes

1972 • 286 citations

Restriction of the Mobility of Lymphocyte Immunoglobulin Receptors by Concanavalin A

1972 • 285 citations

Stereochemistry of Cooperative Effects in Hemoglobin

1972 • 282 citations

Ferritin-Conjugated Plant Agglutinins as Specific Saccharide Stains for Electron Microscopy: Application to Saccharides Bound to Cell Membranes

1971 • 275 citations

The contractile ring

1970 • 265 citations

Rhodopsin Rotates in the Visual Receptor Membrane

1972 • 264 citations

A General Theory of Membrane Transport From Studies of Bacteria

1957 • 260 citations

ISOLATION AND PARTIAL CHARACTERIZATION OF LYMPHOCYTE SURFACE IMMUNOGLOBULINS

1972 • 258 citations

DEMONSTRATION OF THE OUTER SURFACE OF FREEZE-ETCHED RED BLOOD CELL MEMBRANES

1970 • 257 citations

Topography of Membrane Concanavalin A Sites modified by Proteolysis

1972 • 257 citations

CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO

1972 • 253 citations

Spin-label studies of the excitable membranes of nerve and muscle.

1968 • 249 citations

Protein conformations in cellular membranes.

1966 • 243 citations

Histones and Basic Polyamino Acids Stimulate the Uptake of Albumin by Tumor Cells in Culture

1965 • 235 citations

THE LOCALIZATION OF SPECTRIN ON THE INNER SURFACE OF HUMAN RED BLOOD CELL MEMBRANES BY FERRITIN-CONJUGATED ANTIBODIES

1971 • 228 citations

Properties of the Insulin Receptor of Isolated Fat Cell Membranes

1971 • 227 citations

Localization of A Antigen Sites on Human Erythrocyte Ghosts

1971 • 225 citations

THE DISTRIBUTION AND ASYMMETRY OF MAMMALIAN CELL SURFACE SACCHARIDES UTILIZING FERRITIN-CONJUGATED PLANT AGGLUTININS AS SPECIFIC SACCHARIDE STAINS

1974 • 223 citations

Binding of Radioactively Labelled Concanavalin A and Wheat Germ Agglutinin to Normal and Virus-transformed Cells

1971 • 214 citations

ANTIGENIC STRUCTURE OF CELL SURFACES

1969 • 212 citations

Temperature-dependent Mobility of Concanavalin a Sites on Tumour Cell Surfaces

1973 • 211 citations

Vascular Injury and Lysis of Basement Membrane in vitro by Neutral Protease of Human Leukocytes

1968 • 211 citations

Rapid Lateral Diffusion of Phospholipids in Rabbit Sarcoplasmic Reticulum

1972 • 210 citations

A Comparative Evaluation of the Distribution of Concanavalin A-Binding Sites on the Surfaces of Normal, Virally-Transformed, and Protease-Treated Fibroblasts

1973 • 206 citations

British Optical Astronomy

1972 • 204 citations

Normal Distribution, Patching and Capping of Lymphocyte Surface Immunoglobulin studied by Electron Microscopy

1973 • 201 citations

THE ISOLATION OF MOUSE HEPATOCYTE GAP JUNCTIONS

1972 • 200 citations

Evidence for a Primary Association between Immunoblasts and Small Gut

1972 • 197 citations

The Molecular Organization of Lipids in the Membrane of Escherichia coli: Phase Transitions

1971 • 191 citations

LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECITLES

1972 • 190 citations

Purification by Means of Detergents and Properties of Cytochrome b5 from Liver Microsomes

1968 • 185 citations

Distribution of Saccharide Residues on Membrane Fragments from a Myeloma-Cell Homogenate: Its Implications for Membrane Biogenesis

1972 • 185 citations

Characterization of the plasma membrane of Mycoplasma laidlawii. VII. Phase transitions of membrane lipids

1970 • 179 citations

Stimulation of Glucose Transport in Cultures of Density-Inhibited Chick Embryo Cells

1971 • 177 citations

Temperature-Dependent Alterations in Sugar Transport in Cells Infected by a Temperature-Sensitive Mutant of Rous Sarcoma Virus

1971 • 168 citations

Antigen Cap Formation in Cultured Fibroblasts: A Reflection of Membrane Fluidity and of Cell Motility

1972 • 167 citations

FLUIDITY OF THE SURFACE OF CULTURED MUSCLE FIBERS

1973 • 162 citations

Isolation and characterization of a water-soluble protein from bovine erythrocyte membranes

1971 • 161 citations

CELL SURFACE IMMUNOGLOBULIN

1972 • 158 citations

CRITICAL ROLE OF DETERMINANT PRESENTATION IN THE INDUCTION OF SPECIFIC RESPONSES IN IMMUNO-COMPETENT LYMPHOCYTES

1973 • 155 citations

Red cell membrane glycoprotein: Amino acid sequence of an intramembranous region

1972 • 150 citations

Planar liquid-like arrangement of photopigment molecules in frog retinal receptor disk membranes

1969 • 150 citations

The Release of Granule Enzymes from Human Neutrophils Stimulated by Aggregated Immunoglobulins of Different Classes and Subclasses

1972 • 147 citations

Studies on antigen-binding cells

1970 • 140 citations

INDUCTION OF IMMUNITY AND TOLERANCE IN VITRO BY HAPTEN PROTEIN CONJUGATES

1972 • 139 citations

Opportunities for Collaboration in Europe

1971 • 139 citations

Government Survey Raises Unemployment Spectre

1971 • 136 citations

The cytochalasins as research tools in cytology.

1972 • 132 citations

Electron Mircroscopy of the Immunoglobulins

1969 • 130 citations

The Location of Photopigment Molecules in the Cross-Section of Frog Retinal Receptor Disk Membranes

1972 • 124 citations

Immunological Enhancement: A Study of Blocking Antibodies

1972 • 120 citations

LYMPHOCYTE MEMBRANE DYNAMICS

1971 • 118 citations

THE RELATIONSHIP OF CONCANAVALIN A BINDING TO LECTIN-INITIATED CELL AGGLUTINATION

1973 • 116 citations

ELECTRON MICROSCOPIC LOCALIZATION OF IMMUNOGLOBULIN E ON THE SURFACE MEMBRANE OF HUMAN BASOPHILS

1971 • 113 citations

A FLUID LIPID‐GLOBULAR PROTEIN MOSAIC MODEL OF MEMBRANE STRUCTURE*

1972 • 109 citations

MECHANISMS UNDERLYING BINDING OF IMMUNE COMPLEXES TO MACROPHAGES

1971 • 106 citations

Dissolution of erythrocyte membranes in water and comparison of the membrane protein with other structural proteins.

1968 • 105 citations

Lymphocyte Interactions in Antibody Responses

1972 • 105 citations

H-2 Histocompatibility alloantigens. Biochemical properties of the molecules solubilized by NP-40 detergent

1973 • 105 citations

Protein-Protein Interactions

1972 • 102 citations

Dissociation of M- and N-group mucoproteins in subunits in detergen solutions

1964 • 102 citations

STRUCTURAL PROTEINS OF MEMBRANE SYSTEMS

1963 • 93 citations

The Antigen System of Paramecium aurelia

1957 • 91 citations

Structure and Role of the Five Glycopeptides of Human IgM Immunoglobulins

1971 • 90 citations

DIRECT DEMONSTRATION OF THETA-POSITIVE ANTIGEN-BINDING CELLS, WITH ANTIGEN-INDUCED MOVEMENT OF THYMUS-DEPENDENT CELL RECEPTORS

1973 • 89 citations

Quantitative Two-Dimensional Ultrastructural Distribution of Rh _o (D) Antigenic Sites on Human Erythrocyte Membranes ^*

1971 • 84 citations

Advances in Calcitonin Research

1971 • 83 citations

Circular dichroism and the conformations of membrane proteins. Studies with red blood cell membranes

1971 • 82 citations

Quantitation of N-acetyl-d-galactosamine-like sites on the surface membrane of normal and transformed mammalian cells

1971 • 80 citations

Phospholipid Requirement for Rh Antigenic Activity

1968 • 78 citations

H-2 Antigen on Cell Membranes: An Explanation for the Alteration of Distribution by Indirect Labeling Techniques

1972 • 76 citations

Dynamics of the Membrane of Amoeba Proteus Studied with Labelled Specific Antibody

1962 • 75 citations

Red cell hydrolases

1972 • 75 citations

Redistribution of Surface Antigens– a General Property of Animal Cells?

1972 • 72 citations

VISUALIZATION OF ANTIGENIC SITES OF HUMAN ERYTHROCYTES WITH FERRITIN-ANTIBODY CONJUGATES

1964 • 70 citations

Erythrocyte membrane sulfhydryl groups and Rh antingen activity

1967 • 69 citations

Antigen Recognition: Early Surface-Receptor Phenomena Induced by Binding of a Tritium-Labeled Antigen

1972 • 68 citations

IMMUNOGLOBULINS ON THE SURFACE OF THYMUS-DERIVED CELLS ENGAGED IN THE INITIATION OF A HUMORAL IMMUNE RESPONSE

1971 • 68 citations

Microspikes on the Lymphocyte Uropod

1969 • 68 citations

Induction of immunity and tolerance in vitro by hapten protein conjugates. II. Carrier independence of the response to dinitrophenylated polymerized flagellin

1972 • 65 citations

Metabolic characteristics of lymphocyte surface immunoglobulins

1972 • 65 citations

Correction of the Amino Acid Sequence of Calf Liver Microsomal Cytochrome b5

1969 • 64 citations

Synthesis of the plasma membrane of the liver cell

1968 • 62 citations

ANTIGEN BINDING AND CAPPING BY LYMPHOCYTES OF GENETIC NONRESPONDER MICE

1972 • 62 citations

COMPOSITION OF CELLULAR MEMBRANES IN THE PANCREAS OF THE GUINEA PIG

1972 • 61 citations

Isolation of the Fundamental Polypeptide Subunits of Biological Membranes

1970 • 61 citations

Increased transport of 2-aminoisobutyric acid in rat lymphocytes stimulated with concanavalin A

1973 • 60 citations

Reversible Inhibition of Lymphocyte-mediated Cytotoxicity by Cytochalasin B

1972 • 60 citations

Micromorphologic consequences following perturbation of erythrocyte membranes by trypsin, phospholipase A, lysolecithin, sodium dodecyl sulfate and saponin A correlated freeze-etching and biochemical study

1972 • 58 citations

Histochemistry and Cytochemistry

1983 • 57 citations

Fractionation of Antigen Reactive Cells on a Cellular Immunoadsorbent: Factors Determining Recognition of Antigens by T-Lymphocytes

1972 • 56 citations

Characterization of the plasma membrane of Mycoplasma laidlawii. IV. Structure and composition of membrane and aggregated components

1968 • 55 citations

Response of an Escherichia coli -Bound Fluorescent Probe to Colicin E1

1970 • 54 citations

DEMONSTRATION OF SURFACE ANTIGENS AND PINOCYTOSIS IN MAMMALIAN CELLS WITH FERRITIN-ANTIBODY CONJUGATES

1962 • 53 citations

Interaction of Human Growth Hormone and Human Erythrocyte Membranes Studied by Intrinsic Fluorescence

1971 • 53 citations

Modulation of TL (thymus-leukemia) antigens by Fab-fragments of TL antibody.

1968 • 52 citations

The Molecular Basis of Codominant Expression of the Histocompatibility-2 Genetic Region

1972 • 51 citations

The behaviour of lymphocytes in the process of target cell destruction in vitro

1968 • 50 citations

Location of amino acid and carbohydrate transport sites in the surface membrane of normal and transformed mammalian cells

1971 • 50 citations

The phosphorylation and isolation of two erythrocyte membrane proteins in, vitro

1972 • 48 citations

Electron microscopic studies of human monocyte and lymphocyte interaction with immunoglobulin- and complement-coated erythrocytes

1972 • 46 citations

THE TWO-DIMENSIONAL TOPOGRAPHIC DISTRIBUTION OF H-2 HISTOCOMPATIBILITY ALLOANTIGENS ON MOUSE RED BLOOD CELL MEMBRANES

1971 • 43 citations

Lymphocyte--target cell interaction in vitro. Ultrastructural and cinematographic studies.

1970 • 42 citations

Release of Cell Surface Immunoglobulin by Mouse Splenic Lymphocytes

1972 • 39 citations

Architecture and Topography of Biologic Membranes

1973 • 39 citations

A study of intact human erythrocytes and their ghosts using stearic acid spin labels

1972 • 38 citations

The structure and chemistry of mammalian cell membranes.

1971 • 38 citations

PINOCYTOTIC RESPONSE OF CIRCULATING ERYTHROCYTES TO SPECIFIC BLOOD GROUPING ANTIBODIES

1968 • 37 citations

Brownian rotation of the cytochrome oxidase in the mitochondrial inner membrane

1972 • 35 citations

Intramembraneous Marker in T Lymphocytes

1972 • 33 citations

Studies on the Mechanism of Binding of Immune Complexes to Phagocytes

1969 • 29 citations

Modulation of TL (Thymus-Leukemia) Antigens by Fab-Fracments of TL Antibody

1968 • 29 citations

Binding and Vesiculation of Rabbit IgG by Rabbit Yolk Sac Membrane

1973 • 20 citations

Variation and Homology in the Mu and Gamma Heavy Chains of Human Immunoglobulins

1971 • 20 citations

The Nature of the Antibody in Iso-Immune Anti-L Sera Affecting Active Potassium Transport in LK Sheep Red Cells

1971 • 20 citations

Reactivity of anti-D Immunoglobulin G Subunits

1970 • 19 citations

Prevention of Atherosclerosis: A Pediatric Problem

1973 • 17 citations

Ultrastructural distribution of surface immunoglobulin determinants on mouse lymphoid cells

1972 • 16 citations

Isoantigenic Properties of Tumors Transgressing Histocompatibility Barriers of the H-2 System<xref ref-type="fn" rid="FN2">2</xref>

1964 • 15 citations

Influence of Antigen Receptor Density on Agglutination of Red Blood Cells

1970 • 11 citations

The Immunocyto-Adherence of Rh (D) Positive Erythrocytes to Mononucleated Cells from the Peripheral Blood of Rhesus Isoimmunised Individuals

1971 • 4 citations

Metabolic dependence of red cell shape: Observations with the scanning electron microscope

1972 • 4 citations

ALTERED SURVIVAL TIMES OF MURINE SKIN ALLOGRAFTS FROM CANCER-BEARING DONORS

1968 • 4 citations