The selective peroxisomal proliferator-activated receptor-gamma agonist has an additive effect on plaque regression in combination with simvastatin in experimental atherosclerosis

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial

2002 • 6,780 citations

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

1998 • 3,517 citations

PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

1998 • 2,909 citations

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

1998 • 1,740 citations

Current Concepts of the Pathogenesis of the Acute Coronary Syndromes

2001 • 1,568 citations

Pravastatin Treatment Increases Collagen Content and Decreases Lipid Content, Inflammation, Metalloproteinases, and Cell Death in Human Carotid Plaques

2001 • 995 citations

Peroxisome proliferator–activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor–deficient mice

2000 • 846 citations

Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein

1998 • 733 citations

Effect of HMG-CoA Reductase Inhibitors on Coronary Artery Disease as Assessed by Electron-Beam Computed Tomography

1998 • 697 citations

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.

1994 • 644 citations

Stabilization of atherosclerotic plaques: New mechanisms and clinical targets

2002 • 576 citations

Lipid Lowering by Diet Reduces Matrix Metalloproteinase Activity and Increases Collagen Content of Rabbit Atheroma

1998 • 565 citations

Macrophages in Human Atheroma Contain PPARγ

1998 • 536 citations

The role of PPAR-γ in macrophage differentiation and cholesterol uptake

2001 • 507 citations

Modulation of Vascular Inflammation In Vitro and In Vivo by Peroxisome Proliferator–Activated Receptor-γ Activators

2000 • 504 citations

Effects of Lipid-Lowering by Simvastatin on Human Atherosclerotic Lesions

2001 • 492 citations

Potent Inhibitory Effect of Troglitazone on Carotid Arterial Wall Thickness in Type 2 Diabetes

1998 • 463 citations

Cholesterol Reduction Yields Clinical Benefit

1998 • 462 citations

High-Density Lipoprotein Restores Endothelial Function in Hypercholesterolemic Men

2002 • 448 citations

CLA-1/SR-BI Is Expressed in Atherosclerotic Lesion Macrophages and Regulated by Activators of Peroxisome Proliferator-Activated Receptors

2000 • 424 citations

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.

1994 • 408 citations

Relationship Between Plasma LDL Concentrations During Treatment With Pravastatin and Recurrent Coronary Events in the Cholesterol and Recurrent Events Trial

1998 • 381 citations

PPARγ Activation in Human Endothelial Cells Increases Plasminogen Activator Inhibitor Type-1 Expression

1999 • 370 citations

RAPID COMMUNICATION: Inhibitory Effect of Pioglitazone on Carotid Arterial Wall Thickness in Type 2 Diabetes

2001 • 354 citations

Exploiting the Vascular Protective Effects of High-Density Lipoprotein and its Apolipoproteins

2001 • 304 citations

Measurement of Atherosclerotic Carotid Plaque Size In Vivo Using High Resolution Magnetic Resonance Imaging

1998 • 291 citations

Cholesterol Reduction Yields Clinical Benefit

1995 • 283 citations

Acute coronary syndromes: biology

1999 • 280 citations

Effects of Prolonged Intensive Lipid-Lowering Therapy on the Characteristics of Carotid Atherosclerotic Plaques In Vivo by MRI

2001 • 277 citations

Progression and Regression of Atherosclerotic Lesions

2002 • 237 citations

Noninvasive In Vivo High-Resolution Magnetic Resonance Imaging of Atherosclerotic Lesions in Genetically Engineered Mice

1998 • 226 citations

Statins Reduce Inflammation in Atheroma of Nonhuman Primates Independent of Effects on Serum Cholesterol

2002 • 222 citations

Exploiting the Vascular Protective Effects of High-Density Lipoprotein and Its Apolipoproteins

2001 • 218 citations

Constitutive Activation of Peroxisome Proliferator-activated Receptor-γ Suppresses Pro-inflammatory Adhesion Molecules in Human Vascular Endothelial Cells

2002 • 211 citations

Serial magnetic resonance imaging of experimental atherosclerosis detects lesion fine structure, progression and complications in vivo

1995 • 207 citations

Troglitazone reduces neointimal tissue proliferation after coronary stent implantation in patients with non–insulin dependent diabetes mellitus

2000 • 192 citations

Thiazolidinediones Suppress Endothelin-1 Secretion from Bovine Vascular Endothelial Cells: A New Possible Role of PPARγ on Vascular Endothelial Function

1999 • 186 citations

Control of Vascular Cell Proliferation and Migration by PPAR-γ

2001 • 159 citations

Serial In Vivo MRI Documents Arterial Remodeling in Experimental Atherosclerosis

2000 • 136 citations

Peroxisome proliferator-activated receptor-α activation and high-density lipoprotein metabolism

2001 • 125 citations

Atherosclerotic aortic component quantification by noninvasive magnetic resonance imaging: an in vivo study in rabbits

2001 • 110 citations

MRI of Rabbit Atherosclerosis in Response to Dietary Cholesterol Lowering

1999 • 104 citations

Inhibitory Activity of Clinical Thiazolidinedione Peroxisome Proliferator Activating Receptor-γ Ligands Toward Internal Mammary Artery, Radial Artery, and Saphenous Vein Smooth Muscle Cell Proliferation

2003 • 91 citations

Intimal Smooth Muscle Cells as a Target for Peroxisome Proliferator-Activated Receptor-γ Ligand Therapy

2002 • 60 citations

Improvement by the insulin-sensitizing agent, troglitazone, of abnormal fibrinolysis in type 2 diabetes mellitus

2000 • 41 citations

Deleted Work

1955 • 0 citations