The complete sequence and structural analysis of human apolipoprotein B-100: relationship between apoB-100 and apoB-48 forms.

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

1977 • 2,481 citations

DNA cloning : a practical approach

1985 • 2,302 citations

Why genes in pieces?

1978 • 2,256 citations

Serum Cholesterol, Lipoproteins, and the Risk of Coronary Heart Disease

1971 • 2,055 citations

SUPERCOILED CIRCULAR DNA-PROTEIN COMPLEX IN Escherichia coli : PURIFICATION AND INDUCED CONVERSION TO AN OPEN CIRCULAR DNA FORM

1969 • 1,847 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Use of Helical Wheels to Represent the Structures of Proteins and to Identify Segments with Helical Potential

1967 • 1,178 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

THREE-DIMENSIONAL STRUCTURE OF MEMBRANE AND SURFACE PROTEINS

1984 • 959 citations

Lipoprotein receptors and cholesterol homeostasis

1983 • 755 citations

Human apolipoprotein E. The complete amino acid sequence.

1982 • 731 citations

A molecular theory of lipid—protein interactions in the plasma lipoproteins

1974 • 725 citations

Three different fibronectin mRNAs arise by alternative splicing within the coding region

1983 • 713 citations

Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins].

1980 • 639 citations

Role of lysine residues of plasma lipoproteins in high affinity binding to cell surface receptors on human fibroblasts.

1978 • 621 citations

Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons.

1980 • 586 citations

Cloning and sequence analysis of a cDNA for rat transforming growth factor-α

1985 • 388 citations

Inhibition of lipoprotein binding to cell surface receptors of fibroblasts following selective modification of arginyl residues in arginine-rich and B apoproteins.

1977 • 380 citations

Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene.

1985 • 352 citations

Apolipoprotein B: Structural and Metabolic Heterogeneity

1983 • 351 citations

[3] Comparative analysis of mammalian plasma lipoproteins

1986 • 318 citations

Nucleotide sequence and structure of the human apolipoprotein E gene.

1985 • 289 citations

Human Apolipoprotein B: Structure of Carboxyl-Terminal Domains, Sites of Gene Expression, and Chromosomal Localization

1985 • 280 citations

Isolation and characterization of the human apolipoprotein A-I gene.

1983 • 243 citations

Distribution of apolipoprotein A-I, C-II, C-III, and E mRNA in fetal human tissues. Time-dependent induction of apolipoprotein E mRNA by cultures of human monocyte-macrophages

1985 • 200 citations

Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein.

1981 • 196 citations

RECOMBINANT LIPOPROTEINS: Implications for Structure and Assembly of Native Lipoproteins

1986 • 158 citations

The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III.

1986 • 156 citations

Mapping of antigenic determinants of human apolipoprotein B using monoclonal antibodies against low density lipoproteins.

1982 • 152 citations

Interaction of plasma lipoproteins containing apolipoproteins B and E with heparin and cell surface receptors

1979 • 150 citations

Measurement in vivo of irreversible degradation of low density lipoprotein in the rabbit aorta. Predominance of intimal degradation.

1984 • 129 citations

[19] Isolation of multigene families and determination of homologies by filter hybridization methods

1983 • 128 citations

Immunoregulatory plasma lipoproteins. Role of apoprotein E and apoprotein B.

1980 • 126 citations

Properties of apolipoprotein b in urea and in aqueous buffers the use of glutathione and nitrogen in its solubilization

1981 • 116 citations

Comparison of α-tropomyosin sequences from smooth and striated muscle

1985 • 114 citations

Peptide chain conformation and the glycosylation of glycoproteins

1977 • 111 citations

The monosaccharide composition and sequence of the carbohydrate moiety of human serum low density lipoproteins

1976 • 106 citations

Human apolipoprotein B-100: cloning, analysis of liver mRNA, and assignment of the gene to chromosome 2.

1985 • 96 citations

Parallel expression of the MB19 genetic polymorphism in apoprotein B-100 and apoprotein B-48. Evidence that both apoproteins are products of the same gene.

1986 • 89 citations

Molecular cloning of human LDL apolipoprotein B cDNA

1985 • 78 citations

Human apolipoprotein B cDNA clone isolation and demonstration that liver apolipoprotein B mRNA is 22 kilobases in length.

1985 • 73 citations

A convenient and adaptable microcomputer environment for DNA and protein sequence manipulation and analysis

1986 • 65 citations

A partial cDNA clone for human apolipoprotein B.

1985 • 64 citations

Molecular weights of apoprotein B obtained from human low-density lipoprotein (apoprotein B-PI) and from rat very low density lipoprotein (apoprotein B-PIII)

1985 • 59 citations

Molecular cloning and expression of partial cDNAs and deduced amino acid sequence of a carboxyl-terminal fragment of human apolipoprotein B-100.

1985 • 58 citations

Synthesis, processing, and secretion of apolipoprotein B by the chick liver cell.

1982 • 56 citations

Isolation of a cDNA clone encoding the amino-terminal region of human apolipoprotein B.

1986 • 53 citations

Molecular cloning of human apolipoprotein B cDNA

1985 • 51 citations

Use of hydrophobicity profiles to predict receptor binding domains on apolipoprotein E and the low density lipoprotein apolipoprotein B-E receptor.

1986 • 49 citations

Human apolipoprotein B: identification of cDNA clones and characterization of mRNA

1985 • 48 citations

Human apolipoprotein B: partial amino acid sequence

1984 • 35 citations

[12] Isolation and characterization of apolipoprotein B-48

1986 • 30 citations

Chromosomal localization of the human apolipoprotein B gene and detection of homologous RNA in monkey intestine.

1986 • 27 citations

Complementary DNA derived structure of the amino-terminal domain of human apolipoprotein B and size of its messenger RNA transcript

1986 • 17 citations

Isolation and carbohydrate composition of glycopeptides of human apo low-density lipoprotein from normal and type II hyperlipoproteinemic subjects

1976 • 14 citations