The Role of Microtubules and Microfilaments in Thyroid Secretion

A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

1970 • 3,269 citations

Microfilaments in Cellular and Developmental Processes

1971 • 1,563 citations

Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations

1972 • 1,201 citations

Colchicine-binding protein of mammalian brain and its relation to microtubules

1968 • 1,140 citations

THE MECHANISM OF ACTION OF COLCHICINE

1967 • 1,049 citations

A "MICROTUBULE" IN PLANT CELL FINE STRUCTURE

1963 • 926 citations

Cell Motility by Labile Association of Molecules

1967 • 767 citations

Adenosine Triphosphate-Induced Sliding of Tubules in Trypsin-Treated Flagella of Sea-Urchin Sperm

1971 • 702 citations

FLAGELLAR ELONGATION AND SHORTENING IN CHLAMYDOMONAS

1969 • 636 citations

Methods for the enhancement of image detail and accentuation of structure in electron microscopy

1963 • 569 citations

THE MECHANISM OF ACTION OF COLCHICINE

1967 • 541 citations

New Hypothesis of Insulin Secretion

1968 • 539 citations

Morphological Transformation of Chinese Hamster Cells by Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate and Testosterone

1971 • 529 citations

AXON GROWTH: ROLES OF MICROFILAMENTS AND MICROTUBULES

1970 • 522 citations

Regulation of Axon Formation by Clonal Lines of a Neural Tumor

1970 • 480 citations

THE ROLE OF THREE CYTOPLASMIC FIBERS IN BHK-21 CELL MOTILITY

1971 • 453 citations

Restoration of Several Morphological Characteristics of Normal Fibroblasts in Sarcoma Cells Treated with Adenosine-3′:5′-Cyclic Monophosphate and Its Derivatives

1971 • 440 citations

Evidence for four classes of microtubules in individual cells

1967 • 425 citations

THE MECHANISM OF COLCHICINE INHIBITION OF MITOSIS

1965 • 419 citations

Properties of colchicine binding protein from chick embryo brain. Interactions with vinca alkaloids and podophyllotoxin

1970 • 391 citations

Effect of Cyclic AMP on Release of Lysosomal Enzymes from Phagocytes

1971 • 380 citations

INTRACELLULAR TRANSPORT OF SECRETORY PROTEINS IN THE PANCREATIC EXOCRINE CELL

1968 • 376 citations

Model for Mitosis

1969 • 370 citations

Pancreatic Beta-Cell Web: Its Possible Role in Insulin Secretion

1972 • 360 citations

Transport of Iodide and Other Anions in the Thyroid Gland

1964 • 333 citations

Nucleoside transport in mammalian cells. Inhibition by colchicine

1972 • 323 citations

ISOLATION OF A PROTEIN SUBUNIT FROM MICROTUBULES

1967 • 319 citations

Isolation of Microtubule Protein from Cultured Mouse Neuroblastoma Cells

1970 • 313 citations

Morphology of Microtubules of Plant Cell

1964 • 309 citations

In vitro DIFFERENTIATION OF A MOUSE NEUROBLASTOMA

1969 • 306 citations

The Biochemical Events of Mitosis. II. The in Vivo and in Vitro Binding of Colchicine in Grasshopper Embryos and Its Possible Relation to Inhibition of Mitosis^*

1967 • 291 citations

The binding of vincristine, vinblastine and colchicine to tubulin

1972 • 273 citations

Inhibition of Collagen Secretion from Bone and Cultured Fibroblasts by Microtubular Disruptive Drugs

1972 • 266 citations

THE ASSOCIATION OF A CLASS OF SALTATORY MOVEMENTS WITH MICROTUBULES IN CULTURED CELLS

1970 • 266 citations

Are Cytoplasmic Microtubules Heteropolymers?

1971 • 261 citations

Definition of three classes of binding sites in isolated microtubule crystals

1972 • 249 citations

Microtubules and pigment migration in the melanophores ofFundulus heteroclitus L.

1966 • 247 citations

Cytochalasin B: Inhibition of Glucose and Glucosamine Transport

1972 • 246 citations

Fibrous proteins--neuronal organelles.

1968 • 244 citations

Aggregation of microtubule subunit protein. Effects of divalent cations, colchicine, and vinblastine

1970 • 237 citations

PROPERTIES OF THE PROTEIN SUBUNIT OF CENTRAL-PAIR AND OUTER-DOUBLET MICROTUBULES OF SEA URCHIN FLAGELLA

1968 • 230 citations

CHANGES IN FINE STRUCTURE AND ACID PHOSPHATASE LOCALIZATION IN RAT THYROID CELLS FOLLOWING THYROTROPIN ADMINISTRATION

1965 • 230 citations

Rat Brain Microtubule Protein: Purification and Determination of Covalently Bound Phosphate and Carbohydrate

1972 • 229 citations

Precipitation of Proteins by Vinblastine and Calcium Ions

1970 • 227 citations

Thermal fractionation of outer fiber doublet microtubules into A- and B-subfiber components: A- and B-tubulin

1970 • 221 citations

Some properties of the protein forming the outer fibers of cilia.

1968 • 214 citations

CILIA REGENERATION IN TETRAHYMENA AND ITS INHIBITION BY COLCHICINE

1969 • 213 citations

Cyclic Adenosine 3′:5′-Monophosphate-Stimulated Phosphorylation of Isolated Neurotubule Subunits

1970 • 206 citations

Vinblastine-Induced Precipitation of Microtubule Protein

1969 • 205 citations

The effect of colchicine on the axonal transport of protein in the optic nerve and tract of the rabbit

1969 • 203 citations

SOME PROPERTIES OF THE PROTEIN FORMING THE OUTER FIBERS OF CILIA

1968 • 189 citations

The Purification of Bovine Thyroid Plasma Membranes and the Properties of Membrane-bound Adenyl Cyclase

1971 • 185 citations

ULTRASTRUCTURAL ANALYSIS OF MITOTIC SPINDLE ELONGATION IN MAMMALIAN CELLS IN VITRO

1971 • 184 citations

Microtubule Crystals: A New Biophysical Phenomenon induced by Vinca Alkaloids

1968 • 183 citations

Cytochalasin B: Effects on Cell Morphology, Cell Adhesion, and Mucopolysaccharide Synthesis

1972 • 180 citations

Observations on the substructure of flagellar fibres

1966 • 178 citations

THE UPTAKE AND DIGESTION OF IODINATED HUMAN SERUM ALBUMIN BY MACROPHAGES IN VITRO

1967 • 172 citations

ENDOCYTOSIS IN CHANG LIVER CELLS

1971 • 165 citations

Antithyroid effects of lithium

1970 • 164 citations

The Stimulus-secretion Coupling of Glucose-induced Insulin Release: V. The Participation of a Microtubular-microfilamentous System

1971 • 164 citations

Possible Role of Microtubules in Thyroid Secretion

1970 • 162 citations

A possible role of microtubules in catecholamine release from the adrenal medulla: effect of colchicine, vinca alkaloids and deuterium oxide.

1971 • 161 citations

Ameboid movement induced in cultured macrophages by colchicine or vinblastine

1971 • 158 citations

Membrane Dynamics in the Action of Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate and Testosterone on Mammalian Cells

1972 • 144 citations

LOCALIZATION OF ESTERASE AND ACID PHOSPHATASE IN GRANULES AND COLLOID DROPLETS IN RAT THYROID EPITHELIUM

1964 • 142 citations

Histamine release from rat peritoneal mast cells: inhibition by colchicine and potentiation by deuterium oxide.

1968 • 140 citations

Induction in vitro of Microtubular Crystals by Vinca Alkaloids

1969 • 137 citations

INTERMICROTUBULE BRIDGES IN MITOTIC SPINDLE APPARATUS

1970 • 135 citations

Metabolism of¹²⁵I in the Thyroid Gland Studied with Electron Microscopic Autoradiography

1964 • 134 citations

THE USE OF FORMALDEHYDE-TREATED 131I-ALBUMIN IN THE STUDY OF DIGESTIVE VACUOLES AND SOME PROPERTIES OF THESE PARTICLES FROM MOUSE LIVER

1967 • 133 citations

The cytochalasins as research tools in cytology.

1972 • 132 citations

Inhibition of Release of Dopamine-β-Hydroxylase and Norepinephrine from Sympathetic Nerves by Colchicine, Vinblastine, or Cytochalasin-B

1972 • 132 citations

Effect of Thyroid-stimulating Hormone and Prostaglandins on Thyroid Adenyl Cyclase Activation and Cyclic Adenosine 3',5'-Monophosphate

1969 • 132 citations

ON THE ACTION OF COLCHICINE

1965 • 131 citations

Heterogeneity of Tubulin Subunits

1971 • 130 citations

Cytochalasin B inhibits thyroid secretion

1971 • 130 citations

Role of Contractile Microfilaments in the Release of Histamine from Mast Cells

1972 • 129 citations

THE FATE OF PEPTIDES PINOCYTOSED BY MACROPHAGES IN VITRO

1969 • 127 citations

Antimitotic Substances

1968 • 123 citations

Vinblastine and microtubules

1972 • 122 citations

COLCHICINE-BINDING PROTEIN AND THE SECRETION OF THYROID HORMONE

1972 • 117 citations

The effect of colchicine on the transport of axonal protein in the chicken

1970 • 116 citations

THE MITOTIC APPARATUS

1965 • 114 citations

FLAGELLAR ELONGATION AND SHORTENING IN CHLAMYDOMONAS

1970 • 111 citations

On the association between microtubules and mitochondria within axons

1971 • 106 citations

MECHANISM OF MOVEMENTS OF GRANULES IN MELANOCYTES OF Fundulus heteroclitus

1968 • 104 citations

Origin of Intracellular Colloid Droplets in the Rat Thyroid

1962 • 104 citations

Guanine Nucleotide Associated with the Protein of the Outer Fibers of Flagella and Cilia

1967 • 103 citations

Interactions of tubulin with vinblastine and guanosine triphosphate

1972 • 102 citations

Comparison of the Microtubule Proteins of Neuroblastoma Cells, Brain, and Chlamydomonas Flagella

1971 • 101 citations

THE ANATOMY OF SECRETION IN THE FOLLICULAR CELLS OF THE THYROID GLAND

1963 • 101 citations

HOW MICROTUBULE PATTERNS ARE GENERATED

1971 • 99 citations

Effect of inhibitors of microtubules and microfilaments on dog thyroid slices in vitro

1972 • 98 citations

Endocytosis in thyroid follicle cells

1967 • 97 citations

THE RELATIONSHIP OF CILIA WITH CELL DIVISION AND DIFFERENTIATION

1971 • 96 citations

Stimulation of Steroid Secretion by Antimicrotubular Agents

1973 • 96 citations

The Mode of Action of Dibutyryl Adenosine 3′,5′-Monophosphate on Bone Tissue in Vitro

1971 • 96 citations

Cytochalasin B: Microfilaments and "Contractile" Processes

1971 • 95 citations

Factors Influencing Adenosine 3′,5′-Phosphate Accumulation in Bovine Thyroid Slices

1968 • 92 citations

Differential effects of antimitotic agents on the stability and behavior of cytoplasmic and ciliary microtubules

1968 • 89 citations

Inhibition of Hormone-Sensitive Adenyl Cyclase by Phenothiazines

1970 • 87 citations

Ultrastructure of normal human thyroid.

1970 • 83 citations

Vinblastine and microtubules

1971 • 82 citations

PURIFICATION OF INTACT MICROTUBULES FROM BRAIN

1970 • 81 citations

THE MELANOCYTE MODEL

1971 • 80 citations

On dense bodies and droplets in the follicular cells of the guinea pig thyroid

1966 • 80 citations

X-ray diffraction from microtubules

1971 • 78 citations

Rapid Purification and the Immunological Specificity of Mammalian Microtubular Paracrystals Possessing an ATPase Activity

1970 • 78 citations

Microtubules in the heliozoan axopodium

1970 • 76 citations

Endocytosis in thyroid follicle cells

1967 • 75 citations

Thyroid Secretionin Vitro: Inhibition of TSH and Dibutyryl Cyclic-AMP Stimulated¹³¹I Release by Li⁺1

1971 • 74 citations

COLLOID DROPLET FORMATION IN DOG THYROID IN VITRO

1967 • 73 citations

The early phase of endocytosis in rat thyroid follicle cells.

1970 • 69 citations

Involvement of the microtubule-microfilament system in thyroid secretion

1970 • 69 citations

Structural Aspects of Saltatory Particle Movement

1967 • 67 citations

Cytochalasin B and Release of Growth Hormone

1971 • 64 citations

Extrathyroidal Conversion of Thyroxine to Triiodothyronine in Sheep

1972 • 63 citations

CONCERNING THE UNIVERSALITY OF A MICROTUBULE ANTIGEN IN ANIMAL CELLS

1972 • 62 citations

Rhabdite formation in planaria: The role of microtubules

1967 • 61 citations

Endocytosis in thyroid follicle cells

1967 • 60 citations

Axon elongation

1971 • 59 citations

Vinblastine: Colchicine-like Effects on Human Blood Leukocytes During Phagocytosis

1971 • 59 citations

Colchicine and hormone secretion

1972 • 59 citations

Colchicine, vinblastine and griseofulvin

1971 • 58 citations

Stabilizing effects of D₂O on the microtubular components and needle‐like form of heliozoan axopods: A pressure‐temperature analysis

1971 • 57 citations

Biochemical Disorders in Human Disease

1971 • 57 citations

Effects of colchicine on nucleic acid metabolism during metamorphosis of Tenebrio molitor L. and in some mammalian tissues

1966 • 56 citations

Inhibition of Glucose-Induced Release of Insulin by Aldose Reductase Inhibitors

1972 • 55 citations

Morphological Aspects of Ciliary Motility

1967 • 54 citations

Flagellar Development in the Protozoan Peranema trichophorum,

1967 • 53 citations

Effect of Colchicine onin VitroACTH Release Induced by High K⁺and by Hypothalamus-Stalk-Median Eminence Extract

1971 • 52 citations

Fibrillar proteins from squid axons

1970 • 52 citations

CYTOCHALASIN B AND PIGMENT GRANULE TRANSLOCATION

1972 • 52 citations

Inhibition by colchicine of carbamylcholine induced glycoprotein secretion by the submaxillary gland. A possible mechanism of cholinergic induced protein secretion

1972 • 51 citations

Fine Structure of a Second Kind of Thyroid Follicle in the C₃H Mouse

1969 • 50 citations

Insulin and Microtubules in Rat Adipocytes

1971 • 50 citations

The Substructure of Human Platelet Microtubules

1968 • 50 citations

THE EFFECT OF COLCHICINE ON MIGRATION OF PIGMENT GRANULES IN THE MELANOPHORES OFFUNDULUS HETEROCLITUS

1969 • 50 citations

ASSAY OF THYROTROPIC HORMONE IN HUMAN BLOOD

1948 • 49 citations

Interactions between Catecholamines, 5-Hydroxytryptamine and TSH on the Secretion of Thyroid Hormone

1972 • 48 citations

Association between Synaptic Vesicles and Neurotubules

1969 • 44 citations

Enzymatic activity in tubulin preparations. I. Intrinsic protein kinase activity in lyophilized preparations of tubulin from porcine brain.

1972 • 44 citations

The Hypocalcemic Action of Colchicine

1972 • 44 citations

Endocytosis in thyroid follicle cells

1967 • 43 citations

BINDING OF COLCHICINE-3H TO VINBLASTINE- AND VINCRISTINE-INDUCED CRYSTALS IN MAMMALIAN TISSUE CULTURE CELLS

1971 • 43 citations

Ultrastructural observations on the thyroid gland of Xenopus laevis daudin throughout metamorphosis

1968 • 43 citations

EFFECT OF METABOLIC INHIBITORS UPON IODIDE TRANSPORT IN SHEEP THYROID SLICES*†

1955 • 42 citations

Stimulation by Prostaglandin E₁of Endocytosis and Glucose Oxidation in Canine Thyroid Slices

1970 • 41 citations

Enzymatic activity in tubulin preparations

1972 • 38 citations

Heterogeneity of Tubulin

1971 • 38 citations

The Purification and Properties of a Thyroid-stimulating Factor Isolated from Clostridium perfringens

1967 • 38 citations

A NEW IN VITRO ASSAY FOR THYROIDSTIMULATING HORMONE

1967 • 36 citations

Thyroid Secretionin Vitro: Multiple Actions of Agents Affecting Secretion

1971 • 36 citations

Effect of Chlorpromazine on Thyrotropin-Stimulated Endocytosis and Glucose Oxidation in Canine Thyroid Slices

1969 • 36 citations

Synthesis and Degradation of Microtubule Protein in Synchronized Chinese Hamster Cells

1972 • 35 citations

Influence of mitochondrial inhibitors on the respiration and energy-dependent uptake of iodide by thyroid slices

1968 • 34 citations

The carbohydrate composition of brain microtubule protein

1972 • 34 citations

Effect of colchicine on rat anterior pituitary gland in tissue culture

1972 • 34 citations

Effect of mitosis inhibitors on blood platelet microtubules and aggregation

1971 • 33 citations

An association between microtubules and aligned mitochondria in Nephrotoma spermatocytes

1972 • 31 citations

THE EFFECTS OF VARYING CONCENTRATIONS OF COLCHICINE ON THE PROGRESSION OF GRASSHOPPER NEUROBLASTS INTO METAPHASE

1971 • 31 citations

ELECTRON MICROSCOPIC LOCALIZATION OF ACID PHOSPHATASE IN RAT THYROID FOLLICLE CELLS AFTER STIMULATION WITH THYROTROPIC HORMONE

1965 • 31 citations

Comparison of Early Effects of Thyrotropin and Long-Acting Thyroid Stimulator on Thyroidal Secretion¹

1967 • 29 citations

THE EFFECTS OF PITUITARY AND NON-PITUITARY GLAND FACTORS ON THE FORMATION OF INTRACELLULAR COLLOID DROPLETS IN THE THYROID EPITHELIUM OF HYPOPHYSECTOMIZED RATS¹

1948 • 29 citations

A COMPARISON OF THE IN-VITRO ACTIONS OF THYROID-STIMULATING HORMONE AND CYCLIC 3′,5′-ADENOSINE MONOPHOSPHATE ON THE MOUSE THYROID GLAND

1969 • 28 citations

Lysosomal hydrolases in calf thyroid

1966 • 26 citations

Ultrastructure of the thyroid gland of the cream hamster

1971 • 23 citations

TSH-Induced Thyroxine Release from Puromycin-Blocked Thyroid Glands of Intact Rabbits1

1966 • 22 citations

SYNTHESIS OF A COLCHICINE-BINDING PROTEIN DURING THE HELA CELL LIFE CYCLE

1969 • 21 citations

Structure-activity relationships in a series of colchicine analogs.

1965 • 21 citations

Origin and fate of colloid droplets of the thyroid gland. A study using iodine-125 electron microscopy autoradiography.

1965 • 19 citations

Cytochalasin B, pituitary metabolism, and the release of ox growth hormone in vitro

1972 • 18 citations

BIOLOGICAL MACROMOLECULES

1979 • 16 citations

Effects of Actinomycin D, Cycloheximide and Puromycin on Thyroid Stimulation¹

1968 • 15 citations

Properties of microtubule proteins in different organelles in Tetrahymena pyriformis

1971 • 12 citations

Dissociation of thyrotropin-stimulated hormone secretion and glucose oxidation in thyroid glands by lithium and colchicine

1971 • 11 citations

Some Effects of Actinomycin D on Iodine Metabolism in the Rat Thyroido

1966 • 11 citations

Endocytosis of Thyreoglobulin and the Release of Thyroid Hormone

1968 • 7 citations