Lysosomes and Related Particles

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

1955 • 4,109 citations

Histochemistry: Theoretical and Applied

1961 • 3,064 citations

Histochemistry of Hepatic Phosphatases at a Physiologic pH: With Special Reference to the Demonstration of Bile Canaliculi

1957 • 1,831 citations

Microscopic histochemistry; principles and practice

1952 • 1,079 citations

The Kinetics of Cellular Proliferation

1960 • 948 citations

Subcellular Particles

1959 • 799 citations

THE ENDOPLASMIC RETICULUM

1956 • 775 citations

THE ISOLATION AND PROPERTIES OF THE SPECIFIC CYTOPLASMIC GRANULES OF RABBIT POLYMORPHONUCLEAR LEUCOCYTES

1960 • 708 citations

Tissue fractionation studies. 5. The association of acid phosphatase with a special class of cytoplasmic granules in rat liver

1955 • 625 citations

GLOMERULAR PERMEABILITY

1961 • 585 citations

THE CONCEPTS OF MEMBRANE FLOW AND MEMBRANE VESICULATION AS MECHANISMS FOR ACTIVE TRANSPORT AND ION PUMPING

1956 • 450 citations

Electron microscopy of the tracheal ciliated mucosa in rat

1956 • 421 citations

An Electron Microscopic Study of the Intestinal Villus

1959 • 408 citations

An Electron Microscope Study of the Rat Ovum

1959 • 386 citations

Tissue fractionation studies. 15. Intracellular distribution and properties of β-N-acetylglucos-aminidase and β-galactosidase in rat liver

1960 • 379 citations

The histochemical recognition of lipine.

1946 • 376 citations

Human hepatocellular pigments and lysosomes

1960 • 354 citations

DEGRANULATION OF POLYMORPHONUCLEAR LEUCOCYTES FOLLOWING PHAGOCYTOSIS OF MICROORGANISMS

1960 • 337 citations

Rate And Magnitude Of Age Pigment Accumulation In The Human Myocardium

1959 • 336 citations

Handbook of Aging and the Individual

1961 • 334 citations

The liver cell

1960 • 329 citations

Factors governing the validity of staining methods for enzymes, and their bearing upon the Gomori acid phosphatase technique*1

1959 • 318 citations

"MICROBODIES" AND THE PROBLEM OF MITOCHONDRIAL REGENERATION IN LIVER CELLS

1956 • 317 citations

Distribution of periodic acid-reactive carbohydrates in the adult rat

1950 • 316 citations

The effect of hypervitaminosis A on embryonic limb‐bones cultivated in vitro

1952 • 316 citations

ELECTRON MICROSCOPY OF LYSOSOME-RICH FRACTIONS FROM RAT LIVER

1956 • 311 citations

Developing Cell Systems and Their Control.

1961 • 298 citations

THE FINE STRUCTURE OF THE RENAL GLOMERULUS OF THE MOUSE

1955 • 294 citations

HEMOGLOBIN ABSORPTION BY THE CELLS OF THE PROXIMAL CONVOLUTED TUBULE IN MOUSE KIDNEY

1960 • 278 citations

Tissue fractionation studies. 12. Intracellular distribution of some dehydrogenases, alkaline deoxyribonuclease and iron in rat-liver tissue

1959 • 275 citations

Tissue fractionation studies. 1. The existence of a mitochondria-linked, enzymically inactive form of acid phosphatase in rat-liver tissue

1951 • 262 citations

Histochemistry with Labeled Antibody

1956 • 247 citations

A Simple Azo-Dye Method for Histochemical Demonstration of Acid Phosphatase

1960 • 224 citations

Fundamental aspects of normal and malignant growth

1960 • 219 citations

The fine structure of young and old spinal ganglia

1955 • 216 citations

Tissue fractionation studies. 10. Influence of ischaemia on the state of some bound enzymes in rat liver

1959 • 214 citations

THE INFLUENCE OF PHAGOCYTOSIS ON THE INTRACELLULAR DISTRIBUTION OF GRANULE-ASSOCIATED COMPONENTS OF POLYMORPHONUCLEAR LEUCOCYTES

1960 • 209 citations

Tissue fractionation studies. 2. The nature of the linkage between acid phosphatase and mitochondria in rat-liver tissue

1951 • 207 citations

CELL HETEROGENEITY WITHIN THE HEPATIC LOBULE OF THE RAT (STAINING REACTIONS)

1959 • 201 citations

The Use of Differential Centrifugation in the Study of Tissue Enzymes

1954 • 198 citations

A study of the mechanism of pinocytosis

1958 • 193 citations

Comparative studies on the liver sulphatases

1958 • 189 citations

Tissue fractionation studies. 13. Analysis of mitochondrial fractions from rat liver by density-gradient centrifuging

1959 • 189 citations

CELLULAR REACTIONS TO A DYE-PROTEIN WITH A CONCEPT OF THE MECHANISM OF ANTIBODY FORMATION

1939 • 184 citations

BIOCHEMICAL HETEROGENEITY OF THE CYTOPLASMIC PARTICLES ISOLATED FROM RAT LIVER HOMOGENATE

1953 • 184 citations

Histochemical Evidence of Intense Phosphatase Activity in the Hypothalamic Magnocellular Nuclei of the Rat

1951 • 183 citations

Electron Microscopic Study of the Phagocytosis Process in Lung

1960 • 172 citations

An Electron Microscopic Study of Erythrophagocytosis

1960 • 170 citations

AN ELECTRON MICROSCOPE STUDY OF THE HEPATIC UPTAKE AND EXCRETION OF SUBMICROSCOPIC PARTICLES INJECTED INTO THE BLOOD STREAM AND INTO THE BILE DUCT

1958 • 166 citations

Biology of pyelonephritis

1961 • 164 citations

Developmental Cytology.

1960 • 162 citations

CONCENTRATION OF ACID PHOSPHATASE, RIBONUCLEASE, DESOXYRIBONUCLEASE, ß-GLUCURONIDASE, AND CATHEPSIN IN "DROPLETS" ISOLATED FROM THE KIDNEY CELLS OF NORMAL RATS

1956 • 160 citations

Segregation of Ferritin in Glomerular Protein Absorption Droplets

1960 • 160 citations

Pinocytosis

1959 • 152 citations

CELL PHYSIOLOGY OF NEOPLASIA

1961 • 151 citations

Cytological observations on the fine structure of the guinea pig ovary with special reference to the oogonium, primary oocyte and associated follicle cells

1960 • 150 citations

INTRACELLULAR DISTRIBUTION OF ENZYMES

1952 • 149 citations

The Proximal Tubule Cell in Experimental Hydronephrosis

1959 • 135 citations

ISOLATION AND BIOCHEMICAL PROPERTIES OF DROPLETS FROM THE CELLS OF RAT KIDNEY

1954 • 133 citations

CYTOCHEMICAL OBSERVATIONS ON CHICKEN MONOCYTES MACROPHAGES AND GIANT CELLS IN TISSUE CULTURE

1953 • 130 citations

The Biochemistry of Development

1960 • 129 citations

UPTAKE AND TRANSFER OF PARTICULATE MATTER FROM THE PERITONEAL CAVITY OF THE RAT

1956 • 128 citations

THE HISTOCHEMICAL DEMONSTRATION OF ACID PHOSPHATASE BY A POST-INCUBATION COUPLING TECHNIQUE

1955 • 123 citations

Phagotrophy and Two New Structures in the Malaria Parasite Plasmodium berghei

1959 • 121 citations

A Comparison of the Intracellular Composition of Regenerating Liver and Induced Liver Tumors

1950 • 121 citations

Intracellular localization of catalase and some oxidases in rat liver

1960 • 118 citations

The Ultrastructure of Mouse Lung: The Alveolar Macrophage

1958 • 114 citations

HISTOCHEMICAL METHODS FOR ACID PHOSPHATASE

1956 • 114 citations

MITOCHONDRIA ASSOCIATED WITH THE KINETONUCLEUS OF TRYPANOSOMA MEGA

1960 • 113 citations

Electron Microscope Studies on Amoebae

1959 • 110 citations

Rapid Cytochemical Identification of Phagosomes in Various Tissues of the Rat and their Differentiation from Mitochondria by the Peroxidase Method

1959 • 110 citations

THE LOCALIZATION OF ENZYME ACTIVITIES IN THE RAT BRAIN

1960 • 110 citations

COMPARISON OF THE EFFECTS OF PAPAIN AND VITAMIN A ON CARTILAGE

1960 • 108 citations

HISTOCHEMICAL DEMONSTRATION OF MITOCHONDRIAL ADENOSINE TRIPHOPHATASE WITH THE LEAD-ADENOSINE TRIPHOSPHATE TECHNIQUE

1960 • 108 citations

Intracellular phagotrophy by malaria parasites: an electron microscope study of Plasmodium lophurae*

1957 • 107 citations

Tissue fractionation studies. 9. Enzymic release of bound hydrolases

1959 • 107 citations

THE EXISTENCE OF A CYTOSTOME AND THE OCCURRENCE OF PINOCYTOSIS IN THE TRYPANOSOME, TRYPANOSOMA MEGA

1960 • 104 citations

HISTOCHEMISTRY OF HUMAN ESTERASES

1955 • 99 citations

Tissue fractionation studies. 11. Influence of various hepatotoxic treatments on the state of some bound enzymes in rat liver

1959 • 99 citations

An electron microscopic study ofAmoeba proteus

1959 • 99 citations

Electron microscopic observations on transitional epithelium of the mouse urinary bladder

1960 • 97 citations

Hypothalamic neurosecretion in the dog and cat, with particular reference to the identification of neurosecretory material with posterior lobe hormone.

1955 • 95 citations

The localization of phosphatases in the Golgi region of intestinal and other epithelial cells

1945 • 93 citations

The function of intracellular hydrolases

1959 • 93 citations

Intracellular Localization of Esterase in Rat Liver

1956 • 92 citations

Ingestion of fluid by Amoeba

1933 • 92 citations

Colorimetric Analysis with N,N-Dimethyl-p-phenylenediamine of the Uptake of Intravenously Injected Horseradish Peroxidase by Various Tissues of the Rat

1958 • 92 citations

Enzymic Content of the Mitochondria Fraction

1953 • 91 citations

Über den Nachweis von hydrolytischen Enzymen in Lipopigmenten

1956 • 89 citations

FLUORESCEIN-CONJUGATED BOVINE ALBUMIN

1953 • 87 citations

On the isolation and some biochemical properties of the Golgi substance

1954 • 85 citations

MICROKINETOSPHERES AND VP SATELLITES OF PINOCYTIC CELLS OBSERVED IN TISSUE CULTURES OF GEY'S STRAIN HELA WITH PHASE CONTRAST CINEMATOGRAPHIC TECHNIQUES

1957 • 85 citations

Segregation of an Intravenously Injected Protein by "Droplets" of the Cells of Rat Kidneys

1957 • 81 citations

Genesis of Intracellular Pigment in the Spinal Ganglia of Senile Rats. An Electron Microscope Study

1957 • 79 citations

A new approach to the cytochemical localization of enzymes

1954 • 78 citations

On the biological function of cathepsin in tail tissue ofXenopus larvae

1957 • 78 citations

CHANGES IN "DROPLET" FRACTIONS FROM RAT KIDNEY CELLS AFTER INTRAPERITONEAL INJECTION OF EGG WHITE

1957 • 74 citations

Uptake and Transfer of Macromolecules by Cells with Special Reference to Growth and Development

1956 • 71 citations

THE VALUE OF FUNDAMENTAL STUDIES OF STAINING REACTIONS IN ENZYME HISTOCHEMISTRY, WITH REFERENCE TO INDOXYL METHODS FOR ESTERASES

1956 • 71 citations

A COMPARISON OF MESOTHELIAL CELLS AND MACROPHAGES IN MICE AFTER THE INTRAPERITONEAL INOCULATION OF MELANIN GRANULES

1956 • 70 citations

COLD ACETONE FIXATION FOR ENZYME LOCALIZATION IN FROZEN SECTIONS

1960 • 68 citations

Intracellular Localization of Enzymes

1960 • 67 citations

Tissue Fractionation Studies of Mouse Pancreas

1959 • 67 citations

The cytochemistry of anoxic and anoxic-ischemic encephalopathy in rats. I. Alterations in neuronal lysosomes identified by acid phosphatase activity.

1961 • 66 citations

The Permeability of the Renal Glomeruli of Several Mammalian Species to Labelled Proteins.

1947 • 65 citations

THE DISTRIBUTION AND STORAGE OF BLUE ANTIGENIC AZOPROTEINS IN THE TISSUES OF MICE

1949 • 62 citations

Ultrastructure of mouse uterine surface epithelium under different estrogenic influences

1958 • 61 citations

The release of acid phosphatase and beta-glucuronidase from cytoplasmic granules in the early course of autolysis.

1959 • 59 citations

The Intracellular Location of Phosphoprotein Phosphatase Activity

1959 • 58 citations

ESQUISSE D'UNE HISTOPHYSIOLOGIE COMPARÉE DU REIN DES VERTÉBRÉS

1934 • 54 citations

Intracellular Distribution of Proteolytic Enzymes in Rat Liver Tissue.

1957 • 53 citations

Untersuchungen an isoliertem, unver�ndertem Lipofuscin aus Herzmuskulatur

1955 • 52 citations

Liver: Structure and Function

1957 • 52 citations

CELLULAR MECHANISMS OF PROTEIN METABOLISM IN THE NEPHRON

1954 • 52 citations

HISTOCHEMICAL EVIDENCE OF INTRACELLULAR ENZYMATIC HETEROGENEITY OF PLANT MITOCHONDRIA

1960 • 52 citations

Electron microscopy of four-cell stages of the ascidians Ciona and Styela

1960 • 52 citations

Electron Microscopy of Pinocytosis and Food Vacuoles in Pelomyxa*

1960 • 51 citations

Structural and chemical properties of the plasmalemma of Amoeba proteus

1953 • 50 citations

STUDIES OF EARLY CLEAVAGE IN THE SURF CLAM, SPISULA SOLIDISSIMA, USING METHYLENE BLUE AND TOLUIDINE BLUE AS VITAL STAINS

1959 • 48 citations

A cytochemical survey of phosphatases in mammalian liver, pancreas and salivary glands

1947 • 48 citations

Cytochemical Localisations and Ultrastructure in the Fertilized Unsegmented Egg of Paracentrotus lividus

1958 • 47 citations

THE UPTAKE OF RADIOCOLLOIDS BY MACROPHAGES IN VITRO

1956 • 47 citations

Electron-dense bodies in liver tissue of the mouse in relation to the activity of acid phosphatase

1960 • 47 citations

Biochemical changes in the tissues of animals injected with iron: acid phosphatase and other enzymes

1960 • 47 citations

CELLULAR MECHANISMS OF PROTEIN METABOLISM IN THE NEPHRON

1958 • 47 citations

CELLULAR MECHANISMS OF PROTEIN METABOLISM IN THE NEPHRON

1955 • 46 citations

SOME CYTOCHEMICAL OBSERVATIONS ON HUMAN TESTES AND EPIDIDYMIDES

1952 • 46 citations

The Process of Aging in the Nervous System.

1960 • 46 citations

Lysosomal-like Particles in the Rat Mammary Gland

1960 • 43 citations

On the Appearance of Absorbed Fat Droplets in the Nuclear Envelope

1960 • 43 citations

INTRACELLULAR DIGESTION AND HYDROLYTIC ENZYMES IN THE PHAGOCYTES OF PLANARIANS

1960 • 42 citations

Ultrastructure of mouse uterine surface epithelium under different estrogenic influences

1959 • 42 citations

THE BINDING OF SULPHATASE BY RAT-LIVER PARTICLES AS COMPARED TO THAT OF ACID PHOSPHATASE

1955 • 42 citations

A SUGGESTION AS TO THE NATURE OF THE LYSOSOME GRANULES

1956 • 42 citations

THE INTRACELLULAR LOCALIZATION OF URICASE

1951 • 40 citations

The food canal of the Sea‐urchin Echinus esculentus L. and its functions.*

1955 • 39 citations

Permeation mechanisms in bacterial membranes

1956 • 39 citations

Cytological evidence of protein absorption in fetal and adult mammalian kidneys

1954 • 37 citations

RELATION BETWEEN THE VITALLY STAINED GRANULES AND CLEAVAGE‐ACTIVITY IN THE SEA URCHIN EGG*

1959 • 36 citations

Recherches ultrastructurales sur le virus de la leucémie érythroblastique du poulet

1958 • 34 citations

Histochemical Alterations in Autonomic Ganglion Cells Associated with Aging

1952 • 34 citations

FORMATION OF FOOD-CUPS INAMŒBAINDUCED BY CHEMICALS

1925 • 30 citations

Phosphomonoesterase activity in hepatic tissues of the mouse

1952 • 30 citations

The neurone of the human autonomic system and the so‐called ‘senility pigment’

1951 • 30 citations

Increase of acid phosphatase activity in mouse liver after dextran storage

1959 • 28 citations

Cell division: Experimental induction of cleavage furrows in the eggs of Arbacia punctulata

1960 • 25 citations

Acid and Glucose-6-Phosphatase Activity of Pancreatic B Cells after Cortisone and Sulfonylureas.

1959 • 25 citations

Distribution of some enzymes in the cytoplasm of amoebae

1954 • 25 citations

Le déterminisme de l'atrophie d'un organe rudimentaire: le canal de Müller des embryons mâles d'oiseaux

1953 • 25 citations

The use of thorotrast for the electron microscopic study of phagocytosis

1956 • 24 citations

Hemosiderin Granules in the Choroid Plexus

1959 • 24 citations

Observations on fragmented rat liver canaliculi and the problems of intracellular bile canaliculi and golgi apparatus

1955 • 23 citations

The Golgi apparatus and vital staining of the amphibian and reptilian liver

1932 • 22 citations

Modern Trends in Geriatrics

1957 • 21 citations

The Golgi Apparatus of Liver and Nerve Cells

1951 • 19 citations

The localization of acid phosphatase activity in the ameba, Chaos chaos

1960 • 19 citations

Demonstration Of Golgi Zones By Three Technics For Carbohydrates

1952 • 19 citations

SOME OBSERVATIONS OF THE REACTION OF SCHIFF REAGENT WITH ALDEHYDES

1960 • 18 citations

XVII.—THE DORSAL ROOT GANGLION CELL OF THE KITTEN WITH SUDAN DYES AND THE ZERNICKE MICROSCOPE

1949 • 17 citations

Different Kinds of Acid Phosphatases in Various Cytological Structures of the Anterior Pituitary of the Guinea Pig

1949 • 17 citations

The effect of an amino acid analog on catheptic activity in somite mesoderm of the chick embryo

1960 • 17 citations

CHEMICAL ANALYSES OF ANTERIOR AND POSTERIOR BLASTOMERES OF CIONA INTESTINALIS

1957 • 16 citations

Electron Microscopic Atlas of Normal and Leukemic Human Blood

1959 • 16 citations

ON THE VITALLY STAINABLE GRANULES IN THE EGG OF THE ECHIUROID, URECHIS UNICINCTUS

1959 • 15 citations

A biochemical dissection of ischemic liver necrosis.

1959 • 15 citations

GENETIC INFLUENCES ON ENZYME LOCALIZATION

1959 • 15 citations

NAS-Benzidine Reaction of Blood Cells-New Simple Peroxidase Staining Method Using Nickel-Ammonium Sulfate

1951 • 13 citations

CORRELATION BETWEEN THE MOLECULAR CONFIGURATION OF ORGANIC COMPOUNDS AND THEIR ACTIVE TRANSFER IN LIVING CELLS

1940 • 13 citations

Increase of Esterase Activity during Intracellular Digestion in a Histophagous Ciliate

1960 • 10 citations

Activation of cathepsin in fatty liver

1958 • 8 citations

[Relationships between the activity of acid phosphatase in the pituitary gland and the production of thyrotropic hormone].

1959 • 8 citations

Histochemical Evidence of Intracellular Enzymatic Heterogeneity of Plant Mitochondria

1960 • 6 citations

Fractionation of Brain Extracts for Acid Phosphatase-elevating Activity

1959 • 5 citations

HISTOCHEMICAL PEROXIDASE REACTION IN RAT TISSUES BEFORE AND AFTER INJECTION OF PLANT PEROXIDASE

1959 • 3 citations