Pregnancy-induced hypertension

A Study of Angiotensin II Pressor Response throughout Primigravid Pregnancy

1973 • 1,230 citations

HUMAN ARTERIAL AND VENOUS TISSUES GENERATE PROSTACYCLIN (PROSTAGLANDIN X), A POTENT INHIBITOR OF PLATELET AGGREGATION

1977 • 886 citations

The pharmacologic alteration of renin release.

1980 • 518 citations

Prostaglandin I3 is formed in vivo in man after dietary eicosapentaenoic acid

1984 • 476 citations

Platelet function, thromboxane formation and blood pressure control during supplementation of the Western diet with cod liver oil.

1983 • 408 citations

The pathological response of the vessels of the placental bed to hypertensive pregnancy

1967 • 408 citations

Intrarenal prostaglandin release attenuates the renal vasoconstrictor activity of angiotensin.

1973 • 391 citations

Morphological Changes in the Utero-Placental Bed in Pregnancy Hypertension

1977 • 252 citations

Prostacyclin production during pregnancy: Comparison of production during normal pregnancy and pregnancy complicated by hypertension

1982 • 234 citations

Pressor response to angiotonin in pregnant and nonpregnant women

1961 • 224 citations

Reduced umbilical and placental vascular prostacyclin in severe pre-eclampsia

1980 • 224 citations

FETAL EFFECTS OF REGULAR SALICYLATE INGESTION IN PREGNANCY

1975 • 218 citations

Clinical pharmacology of prostacyclin

1981 • 211 citations

Prostacyclin in pregnancy.

1980 • 187 citations

Vascular reactivity to angiotensin II and norepinephrine in pregnant and nonpregnant women

1965 • 184 citations

Production of Renin by in vitro Cultures of Human Chorion and Uterine Muscle

1968 • 174 citations

EFFECT OF FISH OIL ON PLATELET KINETICS IN PATIENTS WITH ISCHAEMIC HEART DISEASE

1982 • 171 citations

ADMINISTRATION TO MAN OF UK-37,248-01, A SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE

1981 • 168 citations

PLASMA RENIN, RENIN SUBSTRATE, ANGIOTENSIN II, AND ALDOSTERONE IN HYPERTENSIVE DISEASE OF PREGNANCY

1973 • 167 citations

Effect of Prostaglandin Synthetase Inhibitors on Pressor Response to Angiotensin II in Human Pregnancy*

1978 • 156 citations

Fetal and Utero-placental Blood Flow

1983 • 155 citations

Renin concentration in human fetal and maternal tissues

1968 • 152 citations

Influence of blood pressure changes with and without proteinuria upon outcome of pregnancy

1976 • 151 citations

Control of vascular responsiveness during human pregnancy

1980 • 150 citations

HOSPITAL LIBRARIANS

1974 • 146 citations

Prostaglandins and the regulation of uterine blood flow in pregnancy

1974 • 137 citations

Effects of vasoactive autacoids on the human umbilical‐fetal placental vasculature

1984 • 132 citations

Effect of Captopril on Uterine Blood Flow and Prostaglandin E Synthesis in the Pregnant Rabbit

1983 • 131 citations

DECREASED PROSTACYCLIN PRODUCTION: A CHARACTERISTIC OF CHRONIC PLACENTAL INSUFFICIENCY SYNDROMES

1981 • 124 citations

The Response of Blood Pressure to Infusion of Angiotensin II: Relation to Plasma Concentrations of Renin and Angiotensin II

1972 • 113 citations

Stimulation of prostaglandin E synthesis in cultured human umbilical vein smooth muscle cells.

1976 • 111 citations

Uterine blood flow and uterine renin secretion

1972 • 105 citations

Effect of angiotensin II on uterine and systemic vasculature in pregnant sheep.

1981 • 105 citations

Prostacyclin and human foetal circulation

1979 • 95 citations

Prostacyclin (PGI2) in pregnant human uterus

1979 • 94 citations

Medicine and the Law

1983 • 92 citations

Role of prostaglandins, prostacyclin, and thromboxanes in the control of the umbilical-placental circulation.

1980 • 92 citations

Pregnancy Hypertension

1980 • 92 citations

Preeclampsia -- a state of prostaglandin deficiency? Urinary prostaglandin excretion, the renin-aldosterone system, and circulating catecholamines in preeclampsia.

1983 • 89 citations

Inhibition of platelet aggregation by a placental substance with prostacyclin-like activity

1977 • 83 citations

Intravenous infusion of prostacyclin sodium in man: clinical effects and influence on platelet adenosine diphosphate sensitivity and adenosine 3':5'-cyclic monophosphate levels.

1981 • 82 citations

RELATION BETWEEN UMBILICAL PROSTACYCLIN PRODUCTION AND BLOOD-FLOW IN THE FETUS

1983 • 81 citations

VASCULAR REACTIVITY IN NORMAL AND TOXEMIC PREGNANCY

1966 • 80 citations

Uterine prostaglandin E secretion and uterine blood flow in the pregnant rabbit.

1975 • 79 citations

The Uteroplacental Renin-Angiotensin System in Normal and Hypertensive Pregnancy

2015 • 76 citations

Anticonvulsants and thyroid function.

1978 • 73 citations

Pre-eclampsia : the hypertensive disease of pregnancy

1983 • 71 citations

The participation of prostaglandins in the control of renin release.

1979 • 69 citations

Thromboxane A2 in pregnancy and puerperium.

1980 • 68 citations

Possible role for prostacyclin in human parturition

1978 • 66 citations

Placental prostaglandin levels in pre-eclampsia

1976 • 66 citations

Serum arachidonic acid levels in normal and preeclamptic pregnancies

1984 • 65 citations

The effect of prostacyclin on the human umbilical artery

1978 • 62 citations

Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone.

1977 • 60 citations

Effects of indomethacin on sheep uteroplacental circulations and sensitivity to angiotensin II

1978 • 58 citations

Evidence that prostacyclin deficiency is a specific feature in preeclampsia

1984 • 56 citations

HYPERTENSION IN PREGNANCY

1977 • 52 citations

Clinics in Obstetrics and Gynaecology

1985 • 52 citations

Augmentation of Prostaglandin Production by Linoleic Acid in Man

1982 • 51 citations

The effect of angiotensin-II intravenous infusion on plasma renin activity and prostaglandins A, E, and F levels in the uterine vein of the pregnant monkey

1974 • 50 citations

Plasmatic regulation of vascular prostacyclin in pregnancy.

1981 • 50 citations

Preliminary observations on treatment of pregnancy-induced hypertension with a thromboxane synthetase inhibitor

1984 • 49 citations

Prostacyclin producing activity of human umbilical, placental and uterine vessels

1983 • 48 citations

The effect of arachidonic- and eicosapentaenoic acid on the synthesis of prostacyclin-like material in human umbilical vasculature.

1980 • 46 citations

Plasma prostanoids in pregnancy‐induced hypertension

1982 • 45 citations

Prostaglandin E2 attenuates the pressor response to angiotensin II in pregnant subjects but not in nonpregnant subjects

1982 • 45 citations

Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies

1981 • 45 citations

Production of active and inactive renin by cultured explants from the human female genital tract

1982 • 44 citations

PROSTACYCLIN FORMATION BY THE PREGNANT HUMAN MYOMETRIUM

1980 • 43 citations

THE EFFECTS OF DEPRIVATION OF PROSTAGLANDIN PRECURSORS ON VASCULAR SENSITIVITY TO ANGIOTENSIN II AND ON THE KIDNEY IN THE PREGNANT RABBIT

1979 • 43 citations

PLASMA ANGIOTENSIN II AND ALDOSTERONE EXCRETION DURING THE MENSTRUAL CYCLE

1970 • 42 citations

PROSTAGLANDINS IN THE HUMAN UMBILICAL CIRCULATION AT BIRTH

1978 • 40 citations

Correlation of prostacyclin synthesis by human umbilical artery with status of essential fatty acid

1984 • 39 citations

PERIPHERAL VASCULAR REACTIVITY TO ANGIOTENSIN AND NORADRENALINE IN PREGNANT AND NON‐PREGNANT WOMEN

1970 • 37 citations

CONCENTRATIONS OF THE PROSTACYCLIN METABOLITE, 6–KETO–PROSTAGLANDIN F_1α, IN AMNIOTIC FLUID DURING LATE PREGNANCY AND LABOUR.

1979 • 37 citations

Plasma prostaglandins in pregnancy.

1978 • 36 citations

Renal Effects of Angiotensin II Infusions in Normotensive Pregnant and Nonpregnant Women

1963 • 36 citations

Prostaglandins in the human fetal circulation in mid-trimester and term pregnancy

1980 • 35 citations

Depressed placental prostaglandin E1 metabolism in toxemia of pregnancy

1973 • 33 citations

PLASMA RENIN ACTIVITY IN PERIPHERAL AND UTERINE VEIN BLOOD IN PREGNANT AND NON‐PREGNANT WOMEN

1972 • 33 citations

The concentrations of the prostaglandins E and F, 13 14-dihydro-15-0x0-prostaglandin F and thromboxane B2 in tissues obtained from women with and without pre-eclampsia

1979 • 32 citations

Source of prostaglandin precursor in human fetal membranes: Arachidonic acid content of amnion and chorion laeve in diamnionic-dichorionic twin placentas

1983 • 31 citations

The Kidney in Pregnancy: A Review

1983 • 30 citations

AN INVESTIGATION OF THE CELLULAR SOURCE OF RENIN IN HUMAN CHORION

1970 • 30 citations

PROSTAGLANDINS IN UMBILICAL PLASMA AT ELECTIVE CAESAREAN SECTION

1979 • 30 citations

Origin of prostanoids in human amniotic fluid: The fetal kidney as a source of amniotic fluid prostanoids

1983 • 30 citations

Prostacyclin production by human placental cells in short-term culture

1983 • 29 citations

Ultrastructural abnormalities of placental villi in placentae from pregnancies complicated by intrauterine fetal growth retardation: Their relationship to decidual spiral arterial lesions

1980 • 28 citations

The effect of prostaglandin E2 on the cardiovascular response to angiotensin II in pregnant rabbits

1977 • 28 citations

Maternal prostacyclin, thromboxane, and placental blood flow

1983 • 25 citations

Lipoxygenase Activity in Human Uterine and Intrauterine Tissues: New Prospects for Control of Prostacyclin Production in Pre-Eclampsia

1983 • 24 citations

Effects and interactions of prostaglandins E1 and E2 on human chorionic plate arteries

1981 • 23 citations

The Effect of Prostaglandin E2 Upon the Biochemical Response to Infused Angiotensin II in Human Pregnancy

1984 • 21 citations

Ovine placental vascular responses to indomethacin

1979 • 18 citations

Effects of prostaglandins E1, E2, and F2alpha on uterine blood flow in nonpregnant sheep

1978 • 18 citations

Interaction of angiotensin with disseminated intravascular coagulation: a possible mechanism in the genesis of acute renal failure.

1973 • 18 citations

Decrease of angiotensin sensitivity after bed rest and strongly sodium-restricted diet in pregnancy

1983 • 18 citations

Effect of prostaglandin A1 on renal hemodynamics in pregnancy toxemia

1979 • 17 citations

The renin-angiotensin system in pregnancy.

1981 • 17 citations

Prostaglandins and the maternal placental circulation: review and perspectives.

1981 • 16 citations

Pre-Eclampsia. The Hypertensive Disease of Pregnancy

1984 • 16 citations

Generation of angiotensin I by tissues of the human female genital tract

1983 • 16 citations

Platelet sensitivity to a prostacyclin analogue in normal and pathological pregnancy

1984 • 15 citations

Prostanoid synthesis by human umbilical artery

1982 • 15 citations

ANGIOTENSIN RECEPTORS IN BOVINE UMBILICAL ARTERY AND THEIR INHIBITION BY NONSTEROIDAL ANTI‐INFLAMMATORY DRUGS

1981 • 14 citations

Prostaglandin Synthetase in the Human Neonatal Kidney

1980 • 12 citations

Decrease of vascular angiotensin sensitivity by l-dopa during human pregnancy

1981 • 12 citations

The site of renin in the human uterus

1984 • 12 citations

Prostacyclin Production in Whole Blood Throughout Normal Pregnancy

1983 • 12 citations

Angiotensin-II sensitivity and prostaglandin-synthetase inhibition in pregnancy

1981 • 11 citations

Vasoactive substances in the circulation of the pregnant dog during acute fetal ischemia

1973 • 11 citations

6-Keto-PGF1 alpha: concentrations in human umbilical plasma and production by umbilical vessels.

1980 • 11 citations

Hormone production by the early bovine embryo

1983 • 10 citations

Uterine artery blood flow studies in the pregnant monkey.

1976 • 10 citations

The Effect of Essential Fatty Acid and Specific Vitamin Suppliments on Vascular Sensitivity in the Mid-Trimesier of Human Pregnancy

1983 • 8 citations

Therapeutic Use of FGA1Infusions in Severe Pre-Eclampsia-A Major Clinical Potential

1983 • 8 citations

Effect of pregnancy-induced hypertension upon placental prostaglandin metabolism: Decreased prostaglandin F2α catabolism with normal prostaglandin E2 catabolism

1980 • 6 citations

A Prospective Study of Urinary Prostaglandins E in Women with Normal and Hypertensive PmGNancies

1982 • 6 citations

Prostaglandin E₂and the Release of Renin from Human Chorion

1985 • 6 citations

Angidtensin Converting Enzyme in Human Fetal Membranes, Placenta, Amniotic Fluid and Cord Venous Serum

1984 • 5 citations

THE RELATION BETWEEN UMBILICAL CORD TISSUE PROSTAGLANDIN E₂ LEVELS, MODE OF ONSET OF LABOUR, FETAL DISTRESS AND METHOD OF DELIVERY

1977 • 5 citations

The Effect of Prostaglandin E₁on the Pressor Response to Angiotensin II in Second Trimester Human Pregnancy and in the Non-Pregnant Subject

1982 • 4 citations

Acute Inhibition of Vascular Angiotensin Sensitivity by Theophylline in Human Pregnancy

1983 • 4 citations

<b>Correlation of direct and indirect measurements of renin from human myometrium and </b><b>chorion </b>

1982 • 3 citations