Asymmetric localization of Drosophila pair-rule transcripts from displaced nuclei: evidence for directional nuclear export.

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

oskar organizes the germ plasm and directs localization of the posterior determinant nanos

1991 • 804 citations

The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.

1988 • 736 citations

Induction of germ cell formation by oskar

1992 • 643 citations

Gene gating: a hypothesis.

1985 • 599 citations

The intracellular localization of messenger RNAs

1995 • 534 citations

Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype.

1994 • 494 citations

Polarization of both major body axes in Drosophila by gurken-torpedo signalling

1995 • 485 citations

Implications for bcd mRNA localization from spatial distribution of exu protein in Drosophila oogenesis

1994 • 482 citations

Staufen protein associates with the 3′UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner

1994 • 435 citations

Localization of nanos RNA controls embryonic polarity

1992 • 391 citations

A two-step model for the localization of maternal mRNA in Xenopus oocytes: Involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA

1990 • 388 citations

Progression of the cell cycle through mitosis leads to abortion of nascent transcripts

1991 • 379 citations

Spatial distribution of transcripts from the segmentation gene fushi tarazu during Drosophila embryonic development

1984 • 369 citations

Metaphase chromosome structure: Bands arise from a differential folding path of the highly AT-rich scaffold

1994 • 368 citations

Organization of the cytoskeleton in early Drosophila embryos.

1986 • 352 citations

Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta- cytoplasmic actin messenger RNAs to different cytoplasmic compartments [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 2):following 1907]

1993 • 332 citations

RNA on the move: the mRNA localization pathway [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 1):1625]

1993 • 315 citations

Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte

1994 • 293 citations

Multiple steps in the localization of bicoid RNA to the anterior pole of the Drosophila oocyte

1989 • 291 citations

Microtubules mediate the localization of bicoid RNA during Drosophila oogenesis

1991 • 255 citations

A central role for microtubules in the differentiation of Drosophila oocytes

1993 • 252 citations

Requirement of Microfilaments in Sorting of Actin Messenger RNA

1991 • 252 citations

Requirements for autosomal gene activity during precellular stages of Drosophila melanogaster

1988 • 183 citations

The state of engrailed expression is not clonally transmitted during early Drosophila development

1992 • 173 citations

Single mRNAs visualized by ultrastructural in situ hybridization are principally localized at actin filament intersections in fibroblasts.

1994 • 173 citations

Sorting of membrane proteins in the secretory pathway

1993 • 171 citations

Microtubules Are a General Component of mRNA Localization Systems in Drosophila Oocytes

1995 • 166 citations

Apical localization of pair-rule transcripts requires 3′ sequences and limits protein diffusion in the Drosophila blastoderm embryo

1991 • 161 citations

The cytoskeleton and mRNA localization

1992 • 157 citations

Dynamics of the nuclear envelope and of nuclear pore complexes during mitosis in the Drosophila embryo.

1984 • 155 citations

Premature Microtubule-Dependent Cytoplasmic Streaming in cappuccino and spire Mutant Oocytes

1994 • 153 citations

Evidence for channeled diffusion of pre-mRNAs during nuclear RNA transport in metazoans.

1993 • 144 citations

Functional Elements of the Cytoskeleton in the Early Drosophila Embryo

1993 • 144 citations

Cloning of a gene encoding an antigen associated with the centrosome in Drosophila

1988 • 141 citations

Requirements for X-linked zygotic gene activity during cellularization of early Drosophila embryos

1988 • 138 citations

RNA localization along the anteroposterior axis of the Drosophila oocyte requires PKA-mediated signal transduction to direct normal microtubule organization.

1994 • 124 citations

Localized maternal mRNA related to transforming growth factor beta mRNA is concentrated in a cytokeratin-enriched fraction from Xenopus oocytes.

1988 • 123 citations

RNA regulatory element BLE1 directs the early steps of bicoid mRNA localization

1993 • 121 citations

Repression and turnover pattern fushi tarazu RNA in the early Drosophila embryo

1986 • 119 citations

Protein targeting signals

1990 • 119 citations

Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila.

1994 • 115 citations

Role of Oocyte Position in Establishment of Anterior-Posterior Polarity in Drosophila

1994 • 115 citations

Cytoarchitecture and the patterning of fushi tarazu expression in the Drosophila blastoderm.

1987 • 110 citations

Temporal and spatial coordination of chromosome movement, spindle formation, and nuclear envelope breakdown during prometaphase in Drosophila melanogaster embryos.

1990 • 103 citations

bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo

1993 • 97 citations

RNA travel: Tracks from DNA to cytoplasm

1993 • 82 citations

Microtubules are involved in the localization of tau mRNA in primary neuronal cell cultures

1994 • 79 citations

The serendipity alpha gene encodes a membrane-associated protein required for the cellularization of the Drosophila embryo.

1990 • 77 citations

Behavior of structurally divergent α-tubulin isotypes during Drosophila embryogenesis: Evidence for post-translational regulation of isotype abundance

1992 • 59 citations

Mechanisms of chromosome banding

1976 • 58 citations

Zygotic activity of the nullo locus is required to stabilize the actin-myosin network during cellularization in Drosophila

1990 • 57 citations

Localized RNAs Are Enriched in Cytoskeletal Extracts of Drosophila Oocytes

1994 • 24 citations

The zygotic control of Drosophila pair-rule gene expression: I. A search for new pair-rule regulatory loci

1989 • 22 citations

Mechanisms of Intracellular Transcript Localization and Export in Early Drosophila Embryos

1993 • 16 citations

oskar organizes the germ plasm and directs localization of the posterior determinant nanos,

1991 • 12 citations