Back to search

Selective regulation of integrin–cytoskeleton interactions by the tyrosine kinase Src

Data up to Jan 2025

Published1999
Citations257
References37

Total Citations Per Year

Abstract

References (37)

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Cell locomotion and focal adhesions are regulated by substrate flexibility

1997 • 2,930 citations

CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES

1997 • 2,470 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING

1996 • 1,900 citations

Integrins: Emerging Paradigms of Signal Transduction

1995 • 1,591 citations

Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages

1997 • 1,218 citations

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.

1995 • 1,202 citations

Autophosphorylation of the Focal Adhesion Kinase, ppl25FAK, Directs SH2-Dependent Binding of pp60src

1994 • 1,168 citations

Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons

1992 • 895 citations

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

1994 • 844 citations

Tracking kinesin-driven movements with nanometre-scale precision

1988 • 816 citations

Structural interaction of cytoskeletal components

1981 • 766 citations

A Requirement for Caveolin-1 and Associated Kinase Fyn in Integrin Signaling and Anchorage-Dependent Cell Growth

1998 • 720 citations

Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion.

1987 • 653 citations

2.0 Å Crystal Structure of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop and Synergy Region

1996 • 621 citations

Ca2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils

1995 • 555 citations

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

1994 • 525 citations

Integrins and cancer

1996 • 520 citations

Cell migration: regulation of force on extracellular-matrix-integrin complexes

1998 • 443 citations

Integrin affinity modulation

1998 • 440 citations

A micromachined device provides a new bend on fibroblast traction forces

1997 • 396 citations

Shear stress induces spatial reorganization of the endothelial cell cytoskeleton

1998 • 361 citations

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism.

1995 • 324 citations

Antibodies to the conserved cytoplasmic domain of the integrin beta 1 subunit react with proteins in vertebrates, invertebrates, and fungi.

1988 • 323 citations

The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin.

1990 • 282 citations

Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.

1994 • 253 citations

ArgGlyAsp (RGD) peptides and the anti-vitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts*1

1991 • 246 citations

Ligand binding regulates the directed movement of β1 integrins on fibroblasts

1996 • 223 citations

Focal contacts: Transmembrane links between the extracellular matrix and the cytoskeleton

1989 • 193 citations

The distribution of distinct integrins in focal contacts is determined by the substratum composition

1989 • 137 citations

Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity.

1995 • 130 citations

The αvβ3 Integrin Regulates α5β1-mediated Cell Migration toward Fibronectin

1997 • 96 citations

The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/delta T cells.

1991 • 93 citations

Role of β1 and β3 Integrins in Human Smooth Muscle Cell Adhesion to and Contraction of Fibrin Clots In Vitro

1998 • 36 citations

Cited By (0)

No citing papers found in database

Selective regulation of integrin–cytoskeleton interactions by the tyrosine kinase Src (1999) – Nature Cell Biology | Metascience Observatory Explorer