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Binding, Metabolism, and Action of Steroid Hormones in the Central Nervous System

Data up to Jan 2025

Published1975
Citations16
References330

Total Citations Per Year

Abstract

References (330)

Atlas of estradiol‐concentrating cells in the central nervous system of the female rat

1973 • 1,506 citations

The neurosciences. Third study program

1975 • 1,465 citations

Frontiers in Neuroendocrinology, 1969.

1970 • 1,185 citations

Techniques of Autoradiography

1967 • 1,151 citations

The neurosciences. Third study program

1974 • 1,078 citations

Techniques of autoradiography

1967 • 1,044 citations

The Conversion of Testosterone to 5α-Androstan-17β-ol-3-one by Rat Prostate in Vivo and in Vitro

1968 • 1,023 citations

The Neurobiology of the Amygdala

1972 • 817 citations

Regional Neurochemistry

1962 • 815 citations

Estrogen-Receptor Interaction

1973 • 746 citations

Selective Retention of Corticosterone by Limbic Structures in Rat Brain

1968 • 700 citations

Selective Retention of Dihydrotestosterone by Prostatic Nuclei

1968 • 532 citations

A NEW DERIVATIVE OF TRIPHENYLETHYLENE: EFFECT ON IMPLANTATION AND MODE OF ACTION IN RATS

1967 • 456 citations

THE ESTROGEN-PROGESTERONE INDUCTION OF MATING RESPONSES IN THE SPAYED FEMALE RAT1

1939 • 345 citations

Activation of the Male Rat's Sexual Behavior by Intracerebral Implantation of Androgen

1966 • 338 citations

Aromatization of Androstenedione by the Anterior Hypothalamus of Adult Male and Female Rats

1972 • 338 citations

AROMATIZATION OF ANDROSTENEDIONE BY THE DIENCEPHALON1

1971 • 320 citations

Rat Brain Binds Adrenal Steroid Hormone: Radioautography of Hippocampus with Corticosterone

1972 • 309 citations

METHODS IN HORMONE RESEARCH

1964 • 305 citations

Estrogen‐Neurons and estrogen‐neuron systems in the periventricular brain

1970 • 305 citations

Frontiers in Neuroendocrinology, 1973.

1973 • 302 citations

Estradiol-Concentrating Neurons: Topography in the Hypothalamus by Dry-Mount Autoradiography

1968 • 298 citations

A SOLUBLE ANDROGEN RECEPTOR IN THE CYTOPLASM OF RAT PROSTATE

1969 • 293 citations

On the Role of Glial Cells in the Mammalian Nervous System

1974 • 277 citations

SPECIES DIFFERENCES IN ADRENOCORTICAL SECRETION

1953 • 271 citations

Autoradiographic Localization of Radioactivity in Rat Brain after Injection of Tritiated Sex Hormones

1968 • 268 citations

Perspectives in Neuropharmacology

1973 • 261 citations

HIGH RESOLUTION AUTORADIOGRAPHY WITH DRY MOUNTED, FREEZE-DRIED FROZEN SECTIONS COMPARATIVE STUDY OF SIX METHODS USING TWO DIFFUSIBLE COMPOUNDS H-ESTRADIOL AND H-MESOBILIRUBINOGEN

1966 • 256 citations

Rat Estradiol Binding Plasma Protein (EBP)

1971 • 255 citations

Telemetered Recording of Hormone Effects on Hippocampal Neurons

1971 • 254 citations

Control by Estrogen of Genetic Transcription and Translation

1968 • 249 citations

The Intranuclear Metabolism of Testosterone in the Accessory Organs of Reproduction

1970 • 249 citations

Receptor-Proteins for Androgens and the Mode of Action of Androgens on Gene Transcription in Ventral Prostate

1970 • 246 citations

Metabolism of Testosterone and Action of Metabolites on Prostate Glands grown in Organ Culture

1968 • 233 citations

A NON-STEROIDAL ESTROGEN ANTAGONIST l-(p-2-DIETHYLAMINOETHOXYPHENYLH-PHENYL-2-p-METHOXYPHENYL ETHANOL

1958 • 233 citations

Conversion of Androstenedione to Estrone by Neural Tissues from Fetal and Neonatal Rats12

1974 • 226 citations

Diencephalic placement of estradiol and sexual receptivity in the female rat

1962 • 221 citations

Factors influencing sex hormone uptake by rat brain regions. I. Effects of neonatal treatment, hypophysectomy, and competing steroid on estradiol uptake

1970 • 207 citations

Modification of ovulatory mechanisms by postnatal administration of estrogen to the rat

1963 • 204 citations

A Model for the Regulation of Ovulation in the Rat

1969 • 197 citations

ISOLATION AND FRACTIONATION OF RAT BRAIN NUCLEI

1966 • 194 citations

Failure of 5α-Dihydrotestosterone to initiate Sexual Behaviour in the Castrated Male Rat

1970 • 193 citations

Importance of Progesterone to Induction of Sexual Receptivity in Spayed Female Rats.

1942 • 191 citations

Rhinencephalic lesions and behavior in cats. An analysis of the Klüver‐Bucy syndrome with particular reference to normal and abnormal sexual behavior

1957 • 185 citations

Effect of Antibodies to 17β-Estradiol and Progesterone on the Estrous Cycle of the Rat

1969 • 177 citations

Nature of sex hormone effects on rat sex behavior: Specificity of effects and individual patterns of response.

1970 • 177 citations

Estrogen formation in the brain

1972 • 175 citations

SELECTIVE RETENTION OF OESTRADIOL BY CELL NUCLEI IN SPECIFIC BRAIN REGIONS OF THE OVARIECTOMIZED RAT1

1970 • 172 citations

Neural Localization for Androgen Activation of Copulatory Behavior in the Male Rat

1967 • 172 citations

Studies on the Role of Sex Steroids in the Feedback Control of FSH Concentrations in Men1

1973 • 169 citations

Partial Characterization of the Nuclear Reduced Nicotinamide Adenine Dinucleotide Phosphate: Δ4-3-Ketosteroid 5α-Oxidoreductase of Rat Prostate

1971 • 169 citations

Testosterone, androstenedione and dihydrotestosterone: Effects on mating behavior of male rats

1971 • 168 citations

Autoradiographic Localization of Radioactivity in the Rat Brain After the Injection of 1,2-3H-Testosterone

1973 • 160 citations

Preferential Uptake of Estradiol by the Anterior Hypothalamus of the Rat

1967 • 156 citations

Neonatal Androgen Effects on Sexual and Non-Sexual Behavior of Adult Rats Tested Under Various Hormone Regimes

1971 • 156 citations

Hormonal control of sexual receptivity during the estrous cycle of the rat

1970 • 154 citations

THE EXPERIMENTAL INDUCTION OF OESTRUS (SEXUAL RECEPTIVITY) IN THE NORMAL AND OVARIECTOMIZED GUINEA PIG

1936 • 154 citations

SEX DIFFERENCES AND HORMONAL CONTROL OF TESTOSTERONE METABOLISM IN RAT PITUITARY AND BRAIN

1973 • 151 citations

Testosterone metabolism in target tissues: Hypothalamic and pituitary tissues of the adult rat and human fetus, and the immature rat epiphysis

1969 • 151 citations

Testosterone Regulation of Sexual Reflexes in Spinal Male Rats

1967 • 147 citations

Retention of corticosterone by cell nuclei from brain regions of adrenalectomized rats

1970 • 143 citations

Testosterone Cytosol “Receptor” in the Rat Levator Ani Muscle

1972 • 142 citations

Intracerebral androgens and sexual behavior in the male rat

1972 • 141 citations

The transformation of testosterone into dihydrotestosterone by the brain and the anterior pituitary

1972 • 140 citations

Neurons of the Hypothalamus Concentrate [ 3 H]Progesterone or Its Metabolites

1973 • 139 citations

Latency between intravenous injection of progestins and the appearance of estrous behavior in estrogen-treated ovariectomized rats

1972 • 137 citations

Effect of Steroid Hormones, Ovariectomy, Estrogen Pretreatment, Sex and Immaturity on the Distribution of3H-Estradiol

1966 • 136 citations

Gonadotrophin Inhibiting and Anti-Fecundity Effects of Chloramiphene.

1960 • 136 citations

Short Latency Induction of Estrous Behavior with Intracerebral Gonadal Hormones in Ovariectomized Rats

1971 • 134 citations

Autoradiographic Analysis of Estradiol Uptake in the Brain and Pituitary of the Female Rat

1969 • 133 citations

The use of protamine to study [6,7-3H]-oestradiol-17β binding in rat uterus

1970 • 132 citations

THE COMPARATIVE ACTIONS OF TESTOSTERONE PROPIONATE AND 5α-ANDROSTAN17β-OL-3-ONE PROPIONATE ON THE REPRODUCTIVE BEHAVIOUR, PHYSIOLOGY AND MORPHOLOGY OF MALE RATS

1971 • 128 citations

Induction of receptivity in ovariectomized female rats by a single intravenous injection of estradiol-17β

1970 • 128 citations

Male and Female Sexual Responses in Male Rats Given Estradiol Benzoate and 5α-Androstan-17β-ol-3-one Propionate

1974 • 127 citations

Conversion of Progesterone to 5α-Pregnane-3,20-dione and 3α-Hydroxy-5α-pregnan-20-one by Rat Medial Basal Hypothalami and the Effects of Estradiol and Stage of Estrous Cycle on the Conversion*

1973 • 124 citations

Dihydrotestosterone, androstenedione, testosterone: Comparative effectiveness in masculinizing and defeminizing reproductive systems in male and female rats

1970 • 124 citations

AROMATIZATION OF ANDROSTENEDIONE BY LIMBIC SYSTEM TISSUE FROM HUMAN FOETUSES

1971 • 122 citations

AUTORADIOGRAPHY OF SOLUBLE LABELLED COMPOUNDS

1964 • 122 citations

Hormones in Development

1974 • 119 citations

Biosynthesis of Estrogens

1962 • 116 citations

Corticosterone binding to hippocampus: Immediate and delayed influences of the absence of adrenal secretion

1974 • 116 citations

Direct Gonad-Pituitary Feedback: An Analysis of Effects of Intracranial Estrogenic Depots on Gonadotrophin Secretion

1963 • 111 citations

Occurrence and localization of 5α-steroid reductase, 3α- and 17β-hydroxysteroid dehydrogenases in hypothalamus and other brain tissues of the male rat

1971 • 110 citations

Selectivity of estrogen distribution in tissues.

1965 • 110 citations

Stimulation of hemoglobin synthesis in chick blastoderms by certain 5beta androstane and 5beta pregnane steroids.

1967 • 107 citations

Androgen-Concentrating Cells in the Midbrain of a Songbird

1973 • 106 citations

Soluble Corticosterone-Binding Macromolecules Extracted from Rat Brain

1972 • 105 citations

The Heterogeneity of Δ4-3-Ketosteroid Reductases (5α)

1960 • 105 citations

Action of an Estrogen Antagonist on Reproductive Mechanisms in the Rat1

1966 • 104 citations

3H-Estradiol:In VitroBinding to Macromolecules from the Rat Hypothalamus, Anterior Pituitary and Uterus

1970 • 103 citations

Steroid-sensitive neurones in rat brain: Anatomical localization and responses to neurohumours and ACTH

1969 • 101 citations

OESTROGENS IN THE CENTRAL NERVOUS SYSTEM

1965 • 100 citations

Distribution and Metabolism of3H-testosterone in Castrated Male Rats; Effects of Cyproterone, Progesterone and Unlabeled Testosterone

1971 • 99 citations

Relationship Between the Anesthetic and Gestagenic Action and Estrous Behavior-Inducing Activity of Different Progestins

1967 • 96 citations

Steroid Hormones and Brain Function

1973 • 96 citations

Ontogeny of Estradiol-Binding Sites in Rat Brain. II. Characteristics of a Neonatal Binding Macromolecule

1973 • 95 citations

EFFECTS OF CLOMIPHENE ON THE PHYSIOLOGY OF REPRODUCTION IN THE RAT

1964 • 94 citations

A Functional Role for 20α-Hydroxypregn-4-en-3-one in the Rabbit

1967 • 93 citations

Isolation of Brain Cell Nuclei

1972 • 93 citations

Effect of Clomiphene on the Uptake of Estradiol by the Anterior Hypothalamus and Hypophysis

1968 • 91 citations

Stimulation of Mammalian Erythropoiesis by 5β-H Steroid Metabolites

1970 • 91 citations

Nuclear Receptor Estrogen Complex: Accumulation, Retention and Localization in the Hypothalamus and Pituitary1

1973 • 91 citations

Uterine Progesterone Metabolism and Progestational Response: Effects of Estrogens and Prolactin

1971 • 89 citations

FREEZE-DRYING OF SMALL TISSUE SAMPLES AND THIN FROZEN SECTIONS BELOW –60°C A SIMPLE METHOD OF CRYOSORPTION PUMPING

1967 • 88 citations

Neuroendocrine Aspects of Male Reproduction1

1969 • 88 citations

Androgen Accumulation and Binding to Macromolecules in Seminal Vesicles: Inhibition by Cyproterone

1969 • 87 citations

Aromatization in the Central Nervous System of Rabbits: Effects of Castration and Hormone Treatment 1

1973 • 86 citations

Effect of anti-estrogen on steroid induced sexual receptivity in ovariectomized rats

1968 • 84 citations

Effects of a Single Injection of an Estrogen Antagonist on the Estrous Cycle of the Rat1

1968 • 83 citations

Steroid-Sensitive Single Neurons in Rat Hypothalamus and Midbrain: Identification by Microelectrophoresis

1967 • 83 citations

Facilitatory and inhibitory effects of progesterone on sexual responses of spayed guinea pigs.

1966 • 83 citations

Ontogeny of Estradiol-Binding Sites in Rat Brain. I. Appearance of Presumptive Adult Receptors in Cytosol and Nuclei

1973 • 82 citations

Factors influencing sex hormone uptake by rat brain regions. II. Effects of neonatal treatment and hypophysectomy on testosterone uptake

1970 • 77 citations

Differential localization of progesterone uptake in brain, role od sex, estrogen pretreatment and adrenalectomy

1971 • 76 citations

COMPARISON OF THE EFFECT OF NEONATAL ADMINISTRATION OF TESTOSTERONE AND DIHYDROTESTOSTERONE IN THE FEMALE RAT

1972 • 76 citations

An Investigation of Progesterone Receptors in Guinea Pig Vagina, Uterine Cervix, Mammary Glands, Pituitary and Hypothalamus*

1974 • 75 citations

Activation of sexual reflexes in male rats by spinal implantation of testosterone

1968 • 74 citations

Antifertility Activities of Two Diphenyl-Dihydronaphthalene Derivatives

1963 • 74 citations

Ovarian Secretion of Progesterone and 20α-Hydroxypregn-4-en-3-one during Rat Estrous Cycle in Chronological Relation to Pituitary Release of Luteinizing Hormone

1969 • 74 citations

Activation and inhibition of isolation induced inter-male fighting behavior in castrate male CD-1 mice treated with steroidal hormones

1972 • 74 citations

The activation of sexual behaviour by hypothalamic implants of oestrogen

1964 • 73 citations

Sites of Steroid Binding and Action in the Brain

1972 • 73 citations

Estrogen-Topographical Localization of Estrogen-Concentrating Cells in the Rat Spinal Cord Following 3H-Estradiol Administration

1973 • 72 citations

[1,2-3H]progesterone uptake by guinea pig brain and uterus: Differential localization, time-course of uptake and metabolism, and effects of age, sex, estrogen-priming and competing steriods

1972 • 72 citations

Distribution and Biological Effects of Tritiated Estradiol Implanted in the Hypothalamo-Hypophysial Region of Female Rats

1966 • 72 citations

Role of Estrogens in Ovulation: A Study Using the Estrogen-Antagonist, I.C.I. 46,474

1970 • 72 citations

Factors influencing sex hormone uptake by rat brain regions. III. Effects of competing steroids on testosterone uptake

1970 • 71 citations

Factors Affecting Uptake of Estradiol-6,7-3H by the Hypophysis and Hypothalamus

1967 • 70 citations

Adrenal Participation in the Timing of Mating and LH Release in the Cyclic Rat1

1971 • 70 citations

Cellular and subcellular 3H-estradiol localization in the pituitary by autoradiography

1968 • 70 citations

γ-Aminobutyric Acid in the Rat Peripheral Nervous System, Pineal and Posterior Pituitary

1974 • 70 citations

Neonatal androgenization and the development of estrogen responsivity in male and female rats

1971 • 69 citations

MALE AND FEMALE MATING BEHAVIOR IN PREPUBERALLY CASTRATED FEMALE RATS TREATED WITH ANDROGENS1

1942 • 69 citations

A biphasic influence of progesterone on sexual receptivity of spayed female rats☆

1970 • 68 citations

Stereospecific Nuclear and Cytosol Aldosterone-Binding Proteins of Various Tissues

1969 • 67 citations

Estradiol “Receptors” in Hypothalamus and Anterior Pituitary Gland: Inhibition of Estradiol Binding by SH-Group Blocking Agents and Clomiphene Citrate

1970 • 65 citations

Properties of corticosterone-binding macromolecules from rat brain cytosol

1973 • 65 citations

Conversion of Progesterone by Rat Medial Basal Hypothalamic Tissue to 5α-Pregnane-3,20-dione

1971 • 64 citations

THE MECHANISM OF OESTRADIOL BINDING IN RAT HYPOTHALAMUS: EFFECT OF ANDROGENIZATION

1971 • 64 citations

Effects of the Anti-androgen Cyproterone Acetate on Mating Behavior and Seminal Vesicle Tissue in Male Rats

1969 • 64 citations

The formation and metabolism of estrogens in brain tissues.

1975 • 63 citations

On the Mechanism of Androgen Sterilization

1969 • 63 citations

Cellular localization of androgen in the brain and pituitary after the injection of tritiated testosterone

1972 • 60 citations

Uptake of Tritiated Progesterone by the Uterus of the Ovariectomized Guinea Pig

1970 • 60 citations

Testosterone and androstanolone in rat plasma and tissues

1973 • 59 citations

Estrogen Formation by the Isolated Perfused Rhesus Monkey Brain

1973 • 58 citations

Association of 3H Corticosterone-1,2 with Macromolecules extracted from Brain Cell Nuclei

1970 • 58 citations

Anti-estrogen inhibition of androgen induced sexual receptivity in rats

1972 • 58 citations

Effects of diverse androgens on estrous behavior, lordosis reflex, and genital tract morphology in the rat*1

1971 • 57 citations

The effects of the administration of testosterone propionate alone or with phenobarbitone and of testosterone metabolites to neonatal female rats*1

1971 • 57 citations

INHIBITION OF ANDROGEN-STERILIZATION IN THE FEMALE RAT BY ADMINISTRATION OF AN ANTIOESTROGEN

1972 • 56 citations

Concentration of tritium in brain tissue of dogs given [1,2-3H2] cortisol intravenously

1965 • 56 citations

Induction of receptivity in female rats and cats with estrogen and testosterone

1970 • 55 citations

Neural uptake of [1, 2-3H]progesterone in ovariectomized rats, guinea pigs and hamsters: Correlation with species differences in behavioral responsiveness

1973 • 55 citations

PROGESTERONE IN THE EXPERIMENTAL CONTROL OF THE BEHAVIOURAL SEX CYCLE IN THE FEMALE RAT

1967 • 55 citations

The effects of hypothalamic implants of ovarian steroids on oestrous behaviour in rabbits

1966 • 54 citations

Regulatory mechanisms of territorial marking in the Mongolian gerbil.

1973 • 54 citations

INDUCTION OF PSYCHIC ESTRUS IN THE HAMSTER WITH PROGESTERONE ADMINISTERED VIA THE LATERAL BRAIN VENTRICLE1

1949 • 54 citations

Actions of progesterone in the control of sexual receptivity of the spayed female rat.

1967 • 53 citations

Effects of the Anti-androgen Cyproterone Acetate on the Uptake of l,2-8H-testosterone in Neural and Peripheral Tissues of the Castrate Male Rat

1969 • 52 citations

Probable Role of Aromatization in the Induction of Estrous Behavior by Androgens in the Ovariectomized Rabbit

1970 • 52 citations

The effects of progesterone and its metabolites on the induction of sexual receptivity in rats

1972 • 52 citations

MORPHOLOGICAL AND BEHAVIOURAL EFFECTS OF AN 'ANTIANDROGEN' IN MALE RATS

1968 • 51 citations

In Vitro Metabolism of Androgens in Dog Hypothalamus, Pituitary, and Limbic System12

1970 • 51 citations

Etude du récepteur cytoplasmique de la (1,2-3H) testosterone dans l'hypophyse antérieure et l'hypothalamus du rat

1971 • 51 citations

Estrogen receptors in the intact rat.

1968 • 51 citations

CORTICOSTERONE BINDING BY RAT BRAIN CYTOSOL1

1971 • 50 citations

UPTAKE OF INTRAVENOUSLY ADMINISTERED PROGESTERONE, PREGNANEDIONE AND PREGNANOLONE BY THE RAT BRAIN

1968 • 50 citations

Uptake and Retention of Tritiated Estradiol in Brain and Peripheral Tissues of Male, Female and Neonatally Androgenized Female Rats

1969 • 50 citations

Evidence for estradiol binding sites in the hypothalamus—Effect of drugs

1967 • 48 citations

THE UPTAKE IN VIVO OF [1,2-3H]PROGESTERONE BY THE BRAIN AND GENITAL TRACT OF THE RAT

1966 • 48 citations

Influence of gonadal hormones on the hypothalamic integration of courtship behaviour in the Barbary dove.

1970 • 48 citations

Positive and Negative Feedback Effects of Estrogen on Pituitary LH Synthesis and Release in Normal and Androgen-Sterilized Female Rats

1970 • 47 citations

Neonatally Androgenized Females' Responsiveness to Estrogen and Progesterone

1970 • 46 citations

LOCALIZATION OF HORMONES BY AUTORADIOGRAPHY AND OTHER HISTOCHEMICAL TECHNIQUES

1970 • 46 citations

Effects of an estrogen antagonist on behavior and on estrogen retention in neural and peripheral target tissues

1973 • 45 citations

Sexual receptivity in the guinea pig: Inhibitory and facilitatory actions of progesterone and related compounds.

1967 • 45 citations

Uptake and Distribution of Exogenous Testosterone-1,2-3H in Neural and Genital Tissues of the Castrate Guinea Pig1

1967 • 44 citations

INHIBITORY ACTION OF MER-25 ON ANDROGEN-INDUCED OESTROUS BEHAVIOUR IN THE OVARIECTOMIZED RABBIT

1971 • 43 citations

Hypothalamic and Hypophyseal Estradiol-Binding Complexes1

1971 • 43 citations

Effect of diverse estrogens on estrous behavior and genital tract development in ovariectomized rats

1971 • 43 citations

Inhibition of Uterine Receptor Binding of Estradiol by Anti-estrogens (Clomiphene and CL-868)

1968 • 43 citations

Antiandrogen Implanted in Brain Stimulates Male Reproductive System

1967 • 43 citations

Biphasic effects of progesterone on sexual receptivity in the female guinea pig.

1968 • 42 citations

Neonatal androgenization and estrogenization and the hormonal induction of sexual receptivity in rats

1970 • 42 citations

Receptor Estrogen Complex in the Nuclear Fraction of the Pituitary and Hypothalamus of Male and Female Immature Rats

1972 • 42 citations

Neuroanatomical regions relevant to production and analysis of vocalization within the avianTorus semicircularis

1970 • 42 citations

The effect of anti-androgens on aggressive behavior in the gerbil

1970 • 41 citations

Estrogen-Sensitive Neurons and Sexual Behavior in Female Cats

1962 • 41 citations

Behavioral and somatic responses to the antiandrogen cyproterone*1

1971 • 40 citations

Testosterone Metabolism in Target Tissues: Effects of Testosterone and Dihydrotestosterone Injection and Hypothalamic Implantation on Serum LH in Ovariectomized Rats

1972 • 40 citations

Testosterone Concentration in the Male Chick Brain: An Autoradiographic Survey

1973 • 40 citations

EFFECTS OF AN ANTI-ANDROGEN ON THE MATING BEHAVIOUR OF MALE GUINEA-PIGS AND RATS

1966 • 39 citations

11β‐HYDROXYSTEROID METABOLISM BY MOUSE BRAIN AND GLIOMA 261 *

1966 • 38 citations

The effect of testosterone on the sex behavior of female rats.

1940 • 38 citations

Effect of 5-α-Dihydrotestosterone on Gonadotropin Secretion and Estrous Behavior in the Female Wistar Rat

1971 • 38 citations

Development of Estrogen Receptors in the Rat Hypothalamus*

1971 • 37 citations

Estradiol-Concentrating Cells in the Rat Amygdala as Part of a Limbic-Hypothalamic Hormone-Sensitive System

1972 • 37 citations

Sexual behavior in the ovariectomized rabbit after treatment with different amounts of gonadal hormones

1970 • 37 citations

Changes in the Uptake of Tritiated Estradiol in the Hypothalamus and Adenohypophysis of Old Female Rats

1973 • 37 citations

Hypothalamic Mechanisms of Sexual Behavior with Special Reference to Birds

1976 • 36 citations

Localization of Estrogen Receptors in the Rat Hypothalamus

1969 • 35 citations

Localization of androgenic metabolites in the brain of rats administered testosterone or dihydrotestosterone

1972 • 35 citations

Uptake of tritiated steroids in the brain of the duck (Anas platyrhynchos). An autoradiographic study

1972 • 35 citations

Computer analysis of the distribution of [3H]estradiol

1967 • 35 citations

Effects of several pregnane and pregnene steroids on estrous behavior in ovariectomized, estrogen-primed guinea pigs

1972 • 35 citations

Mechanism of estrogen action in relation to carcinogenesis.

1966 • 35 citations

Dissociation of Androgenic Effects on Sexual Morphology and Behavior in Male Rats

1968 • 34 citations

Ciba Foundation Symposium on the Neurological Basis of Behaviour.

1959 • 34 citations

THE IN VITRO CONVERSION OF CORTISOL TO CORTISONE BY SUBCELLULAR BRAIN FRACTIONS OF YOUNG AND ADULT RATS*

1965 • 34 citations

GUINEA PIG COPULATORY REFLEX IN RESPONSE TO ADRENAL STEROIDS AND SIMILAR COMPOUNDS

1955 • 33 citations

Cellular and Subcellular Localization of Radioactivity in the Rat Pituitary after Injection of 1,2-3H-Testosterone using Dry-Autoradiography

1973 • 33 citations

Influence of a Testosterone Antagonist (Cyproterone) on Pituitary and Serum ICSH Content in Juvenile Male Rats

1968 • 33 citations

THE HIPPOCAMPUS AND SEPTAL AREA AS PRIMARY TARGET SITES FOR CORTICOSTERONE1

1972 • 33 citations

Corticoid binding component in rat brain

1972 • 32 citations

Distribution of3H-estradiol in Clomiphene-Treated and Neonatally Androgenized Rats1

1971 • 32 citations

Failure of 5α-Dihydrotestosterone To Elicit Estrous Behavior in the Ovariectomized Rabbit

1970 • 31 citations

Androgen accumulation in hypothalamus and anterior pituitary of male ring doves; influence of steroid hormones

1972 • 31 citations

Neonatal organization of aggression in mice: Correlation of critical period with uptake of hormone*1

1972 • 31 citations

Isolation of Oestradiol “Receptors” from Bovine Hypothalamus and Anterior Pituitary Gland

1969 • 31 citations

SOME FACTORS AFFECTING THE UPTAKE, BINDING AND RETENTION OF [3H]CORTISOL BY THE CHICK EMBRYO RETINA AS RELATED TO ENZYME INDUCTION

1973 • 30 citations

Role of the adrenal in the preferential accumulation of progestin by mesencephalic structures

1971 • 30 citations

Feedback regulation of testicular function in Japanese quail: Testosterone implants in the hypothalamus and adenohypophysis

1972 • 30 citations

Hypothalamic Oestradiol-binding Macromolecules

1969 • 29 citations

Cortisone and Hydrocortisone in Cerebrospinal Fluid

1954 • 29 citations

UPTAKE OF INTRAVENOUSLY‐INJECTED [4‐14C] CORTISOL BY ADULT RAT BRAIN*

1963 • 29 citations

Influence of a Testosterone Antagonist (Cyproterone) on Pituitary and Serum FSH-Content in Juvenile Male Rats

1967 • 29 citations

Hormonal Inputs to Releasing Factor Cells, Feedback Sites

1973 • 29 citations

Presence of Corticosterone and Cortisol in the Central and Peripheral Nervous System of the Cat1

1968 • 29 citations

Further Evidence on the Intrahypothalamic Locus for Androgenization of Female Rats

1973 • 29 citations

Induction of estrous behavior in rabbits by hypothalamic implants of testosterone

1966 • 28 citations

Rat and Mouse Brain Corticosterone

1972 • 28 citations

Regional localization of estrogenic metabolites in the brain of male and female rats

1970 • 28 citations

Steroid Hormone Interaction with Specific Brain Regions

1970 • 28 citations

Alteration of quantitative aspects of sexual reflexes in spinal male dogs by testosterone.

1968 • 28 citations

THE ROLE OF OESTROGENS IN SPONTANEOUS OVULATION: EVIDENCE FOR POSITIVE OESTROGEN FEEDBACK IN THE 4-DAY OESTROUS CYCLE

1970 • 28 citations

EFFECT OF AN OESTROGEN ANTAGONIST ETHAMOXY-TRIPHETOL (MER-25) ON OESTROUS BEHAVIOUR IN RATS

1968 • 27 citations

Acetylation of cortisol by neonatal rat brain in vitro

1967 • 27 citations

Influence of Corticosterone Implantation in Limbic Structure upon Biosynthesis of Adrenocortical Steroid

1968 • 27 citations

Differential antagonism, by MER-25, of behavioral and morphological effects of estradiol benzoate in rats

1972 • 26 citations

Thin Sections cut at Temperatures of −70° to −90° C

1965 • 26 citations

THE ACCUMULATION, RETENTION AND INTERACTION OF OESTRADIOL AND OESTRONE IN CENTRAL NEURAL AND PERIPHERAL TISSUES OF GONADECTOMIZED FEMALE RATS

1972 • 26 citations

Retention of radioactivity in cell nuclei in the hypothalamus of the ring dove after injection of 3H-testosterone

1972 • 26 citations

Decreased Estradiol Binding in the Uterus and Anterior Hypothalamus of Androgenized Female Rats

1971 • 26 citations

Corticosterone-binding molecules in rat brain cytosols: regional distribution

1971 • 26 citations

Changes in3H-estradiol Distribution with Development in the Rat1

1969 • 26 citations

Displacement of 17 -Estradiol from Uterine Receptor Sites by an Estrogen Antagonist

1968 • 25 citations

Mating behavior in the female dog and the effects of estrogen on sexual reflexes

1970 • 25 citations

FURTHER STUDIES ON THE UPTAKE OF LABELLED PROGESTERONE BY THE HYPOTHALAMUS AND PITUITARY OF RATS

1969 • 25 citations

Uptake of oestradiol by the rabbit hypothalamus. Specificity of binding by nuclei in vitro

1970 • 24 citations

Conversion of cortisol to cortisol acetate, cortisone acetate and cortisone by the developing primate brain

1968 • 24 citations

Distribution Curves of <sup>3</sup>H-Testosterone and <sup>3</sup>H-Estradiol in Neonatal Female Rats

1970 • 24 citations

THE LESS-POLAR METABOLITES PRODUCED BY INCUBATION OF TESTOSTERONE-4-14C WITH RAT AND BOVINE BRAIN

1969 • 24 citations

NONSTEROIDAL ESTROGEN ANTAGONISTS

1967 • 24 citations

RADIOACTIVITY IN THE RAT HYPOTHALAMUS AND PITUITARY AFTER INJECTION OF LABELLED PROGESTERONE

1968 • 24 citations

The Tubero-Infundibular Region of the Hypothalamus: A Focus of Testosterone Sensitivity in Male Tree Sparrows (Spizella arborea)

1970 • 24 citations

In vitro accumulation and saturation of 3H-progestins in selected brain regions and in the adenohypophysis, uterus and pineal of the female rat

1973 • 24 citations

Timing of Sexual Behavior in the Female Rat

1970 • 23 citations

The Binding of Corticosterone to Brain Proteins: Diurnal Variation1

1973 • 23 citations

1,2-3H-TESTOSTERONE: DISTRIBUTION AND UPTAKE IN NEURAL AND GENITAL TISSUES OF INTACT MALE, CASTRATE MALE AND FEMALE RATS

1969 • 23 citations

Influence of Intracerebral Progesterone on the Reproductive System of Female Rats

1969 • 23 citations

Estrogen, Androgen, and Glucocorticosteroid Concentrating Neurons in the Amygdala, Studied by Dry Autoradiography

1972 • 22 citations

Studies on Androgen and Estrogen Uptake by Rat Hypothalamus

1973 • 22 citations

Changes in Uptake of3H-estradiol by the Female Rat Brain and Pituitary from Birth to Sexual Maturity

1970 • 22 citations

Gonadal hormones and sexual reflexes in the female rat

1969 • 22 citations

The uptake and metabolism of (1,2-3H)-testoster-one by the brain of functionally hepatectomized and totally eviscerated male rats

1972 • 22 citations

Corticosteroids in human brain

1966 • 22 citations

The Identification of Labelled Structures on Autoradiographs

1973 • 21 citations

THE ROLE OF OESTROGENS IN SPONTANEOUS OVULATION: LOCATION OF SITE OF ACTION OF POSITIVE FEEDBACK OF OESTROGEN BY INTRACRANIAL IMPLANTATION OF THE ANTI-OESTROGEN I.C.I. 46474

1971 • 21 citations

Hormones and Behavior: A Survey of Interrelationships between Endocrine Secretions and Patterns of Overt Response.

1951 • 20 citations

Metabolism of 11-hydroxysteroids by cerebral tissues in vitro

1966 • 19 citations

Role of Oestrogen in Spontaneous Ovulation demonstrated by Use of an Antagonist of Oestrogen, ICI 46,474

1970 • 19 citations

Glucocorticoid Binding Sites in Rat Brain: Subcellular and Anatomical Localizations

1973 • 19 citations

Dissociation of Stimulatory and Synthetic Phases in the Induction of Tyrosine Hydroxylase

1974 • 19 citations

FAILURE OF OVULATION AFTER ADMINISTRATION OF STEROID HORMONES AND HORMONE ANTAGONISTS TO FEMALE RATS DURING THE NEONATAL PERIOD

1974 • 19 citations

MINIMUM DURATION OF TRANS‐SYNAPTIC STIMULATION REQUIRED FOR THE INDUCTION OF TYROSINE HYDROXYLASE BY RESERPINE IN THE RAT SUPERIOR CERVICAL GANGLION

1974 • 18 citations

Metabolism of cortisol-4-C14 and cortisone-4-C14 by rat brain homogenates

1965 • 18 citations

Testicular Maintenance and Its Inhibition in Pituitary-Transplanted Rats1

1967 • 18 citations

INHIBITION OF OVULATION IN THE RAT BY INTRAHYPOTHALAMIC IMPLANTS OF AN ANTIOESTROGEN

1973 • 17 citations

Effects of Progesterone or Cyproterone Acetate on Androgen Uptake in the Brain, Pituitary and Peripheral Tissues

1973 • 17 citations

A Study of Estrogen-Sensitive Hypothalamic Centers Using a Technique for Rapid Application and Removal of Estradiol

1968 • 17 citations

Effects ofCis- andTrans-Clomiphene in the Induction of Sexual Behavior1

1973 • 16 citations

Ontogeny of thein vitroUptake of Tritiated Estradiol by the Hypothalamus of the Female Rat

1972 • 16 citations

Effect of 20α-Hydroxypregn-4-en-3-one on Mating Behavior in Spayed Female Rats

1967 • 15 citations

UPTAKE OF SEX STEROIDS BY THE HYPOTHALAMUS AND ANTERIOR PITUITARY OF PRE- AND NEONATAL RATS

1972 • 15 citations

A MORE EXTENSIVE STUDY ON THE UPTAKE OF LABELLED PROGESTERONE BY THE HYPOTHALAMUS AND PITUITARY GLAND OF RATS

1971 • 15 citations

THE ISO-POLAR METABOLITES PRODUCED BY INCUBATION OF [4-14C]TESTOSTERONE WITH RAT AND BOVINE BRAIN

1970 • 15 citations

Reduced oestradiol-binding capacity of androgen sterilized rats.

1968 • 15 citations

Estrogen dose and the duration of the mating period in cats

1968 • 14 citations

Properties of corticosteroid-21-O-acetyltransferase from the baboon brain

1968 • 14 citations

Failure to Demonstrate Uptake of <sup>3</sup>H-Testosterone by the Hypothalamus of Young Rats

1969 • 14 citations

Accumulation of 3H-progestins in limbic, diencephalic, and mesencephalic regions of mouse brain

1973 • 14 citations

26. THE ROLE OF STEROID HORMONES IN THE CONTROL OF GONADOTROPIN SECRETION IN ADULT FEMALE MAMMALS

1971 • 13 citations

Cortisol from Human Nerve

1963 • 13 citations

Effect of Clomiphene Citrate and Its Isomers on Sexual Behavior in Ovariectomized Rats1

1973 • 13 citations

10. STEROID SEX HORMONES IN THE RAT BRAIN: SPECIFICITY OF UPTAKE AND PHYSIOLOGICAL EFFECTS

1971 • 13 citations

On the mechanism of sexual differentiation of the hypothalamus. Decreased hypothalamic oestrogen sensitivity in androgen-sterilized female rats.

1967 • 12 citations

The estrous cycle of the rat: effects on the accumulation of estrogenic metabolites in brain and peripheral tissues

1972 • 12 citations

IN VITRO UPTAKE OF TRITIATED OESTRADIOL BY THE RAT ANTERIOR HYPOTHALAMUS DURING THE OESTROUS CYCLE

1970 • 12 citations

EFFECT OF ACUTE OVARIECTOMY ON MATING IN THE CYCLIC RAT

1965 • 12 citations

VARIABLE UPTAKE OF TRITIATED OESTRADIOL BY THE ANTERIOR HYPOTHALAMUS IN THE POSTPUBERTAL FEMALE RAT

1969 • 11 citations

Some biological actions of dihydrotestosterone (DHT)

1971 • 11 citations

21. HYPOPHYSIOTROPIC NEURONS IN THE PERIVENTRICULAR BRAIN: TOPOGRAPHY OF ESTRADIOL CONCENTRATING NEURONS

1971 • 10 citations

INHIBITION OF OVULATION BY INTRACRANIAL IMPLANTATION OF PROGESTERONE IN THE 4-DAY CYLIC RAT

1971 • 10 citations

IN VITRO UPTAKE OF TRITIATED SEX STEROIDS BY THE HYPOTHALAMUS OF ADULT MALE RATS TREATED NEONATALLY WITH AN ANTIANDROGEN (CYPROTERONE)

1972 • 9 citations

Distribution of Radioactivity in Different Tissues of Pigs After 3H-Hydrocortisone Injection

1969 • 9 citations

Effects of norethynodrel on the tissue distribution of H3-estradiol- 17β in ovariectomized rats

1970 • 8 citations

The distribution of corticosteroid-21-O-acetyltransferase in the baboon brain

1968 • 8 citations

Sequential Subcellular Localization of Cortisol in Cat Brain

1970 • 8 citations

Effects of Progesterone on Uptake and Retention of <sup>3</sup>H-Testosterone in the Neonatal Female Rat

1973 • 8 citations

24. BIOCHEMICAL STUDIES OF CORTICOSTERONE BINDING TO CELL NUCLEI AND CYTOPLASMIC MACROMOLECULES IN SPECIFIC REGIONS OF THE RAT BRAIN

1971 • 8 citations

Further Studies on the Effect of Exogenous Progesterone and Related Compounds on the Preovulatory Progesterone Secretion in the Rat

1970 • 8 citations

Cellular and subcellular localization of3H-estradiol or its metabolites in the pituitary of the neonatal female rat

1973 • 8 citations

Some Characteristics of Corticosterone Uptake by the Dorsal Hippocampus and the Adenohypophysis in the Rat

1974 • 7 citations

Copulatory Reflex Response to Steroids

1964 • 7 citations

Cortisol acetyltransferase from baboon brain

1968 • 7 citations

Fixation de l'oestradiol 3H dans le télencéphale et le diencéphale chez la souris femelle.

1970 • 6 citations

The Metabolism of Corticosteroids by Incubated and Perfused Brain Tissues

2015 • 6 citations

Oestradiol-binding capacity in neural and non-neural target tissues of neonatally androgenized female rats.

1971 • 6 citations

Chromatographic Studies and Scintillation Counting of Selected Tissues of Mice Injected with Labeled Testosterone

1970 • 6 citations

Neonatal sterilization of rodents with steroid hormones

1971 • 6 citations

Effect of Exogenous Progesterone on the Preovulatory Progesterone Secretion in the Rat

1969 • 5 citations

4. LOCAL EFFECTS OF ADRENAL STEROIDS ON CEREBRAL NEURONS

1971 • 5 citations

The Radioautographic Localization of Exogenous Tritiated Dihydrotestosterone, Testosterone and Oestradiol in the Target Organs of Female and Male Rats

2015 • 5 citations

Progesterone-Sensitive Loci for Blockade of Ovulation in the Hamster

1973 • 5 citations

Hormones and behaviour. A survey of interrelationships between endocrine secretions and patterns of overt response.

1948 • 4 citations

Identical Localization of Oestrogen- and Progestogen-Sensitive Hypothalamic Areas

2015 • 4 citations

Neonatal sterilization of rodents with steroid hormones. I. The uptake of radioactivity from injected estradiol or testosterone propionate in various organs of 5 day old male and female rats.

1970 • 2 citations

The mechanism of the push and pull principle. I. Pharmacological effect of oestrogenic hormone on the cells of the pituitary anterior lobe.

1958 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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Binding, Metabolism, and Action of Steroid Hormones in the Central Nervous System (1975) – Springer eBooks | Metascience Observatory Explorer