Tissue and Species Specificity for Phorbol Ester Receptors

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

1977 • 3,432 citations

The medicinal and poisonous plants of southern and eastern Africa.

1962 • 3,171 citations

The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase.

1975 • 917 citations

The Function and Mechanism of Promoters of Carcinogenesis

1973 • 759 citations

The origin of human cancers

1981 • 653 citations

Some Biological Aspects of Skin Carcinogenesis*

2015 • 640 citations

The Sequential Analysis of Cancer Development

1980 • 613 citations

THE DNA OF CAENORHABDITIS ELEGANS

1974 • 583 citations

Calcium-Binding Proteins

2011 • 582 citations

Development of the reproductive system of Caenorhabditis elegans

1976 • 550 citations

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

1979 • 517 citations

Structural similarities between the Ca2+-dependent regulatory proteins of 3':5'-cyclic nucleotide phosphodiesterase and actomyosin ATPase.

1976 • 517 citations

Calcium-Binding Proteins

1976 • 479 citations

In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: Part 1

1980 • 477 citations

Tumor Promoters and the Mechanism of Tumor Promotion

1980 • 415 citations

Analysis of the constancy of DNA sequences during development and evolution of the nematode Caenorhabditis elegans.

1979 • 383 citations

Specific binding of phorbol ester tumor promoters

1980 • 364 citations

Tumor-Promoting Phorbol Esters Inhibit Binding of Epidermal Growth Factor to Cellular Receptors

1978 • 355 citations

TheAhLocus: Genetic Regulation of the Metabolism of Carcinogens, Drugs, and Other Environmental Chemicals by Cytochrome P-450-Mediated Monooxygenase

1979 • 317 citations

Tumor-promoting Agents in Two-stage Carcinogenesis1

2015 • 296 citations

Specific high affinity cell membrane receptors for biologically active phorbol and ingenol esters

1980 • 274 citations

Multistage Models and Primary Prevention of Cancer

1980 • 262 citations

The effect of phorbol diesters on chicken embryo fibroblasts.

1977 • 236 citations

THE GENETICS OF BEHAVIOUR

1973 • 226 citations

Neurotoxin binding to receptor sites associated with voltage-sensitive sodium channels in intact, lysed, and detergent-solubilized brain membranes.

1979 • 214 citations

Environmental Carcinogenesis: Misconceptions and Limitations to Cancer Control

1979 • 197 citations

Temperature-sensitive developmental mutants of Caenorhabditis elegans

1976 • 170 citations

In Vitro Studies on the Mode of Action of the Phorbol Esters, Potent Tumor Promoters, Part 2

1981 • 168 citations

Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts

1976 • 159 citations

Specific binding of phorbol ester tumor promoters to mouse skin

1980 • 152 citations

Characterization of phorbol ester receptors and their down-modulation in GH4C1 rat pituitary cells.

1981 • 142 citations

Tumor initiation and promotion.

1978 • 135 citations

Cocarcinogenesis and biological effects of tumor promoters.

1982 • 133 citations

Ca2+-dependent regulation of guinea pig brain adenylate cyclase.

1980 • 114 citations

Characterization of specific binding of [3H]phorbol 12,13-dibutyrate and [3H]phorbol 12-myristate 13-acetate to mouse brain.

1980 • 107 citations

The tumor promoter 12‐0‐tetradecanoyl‐phorbol‐13‐acetate enhances the proliferative response of Balb/c‐3T3 cells to hormonal growth factors

1979 • 103 citations

Tumor-Promoting Phorbol Esters Affect Production of Prolactin and Growth Hormone by Rat Pituitary Cells*

1981 • 98 citations

The tigliane, daphnane and ingenane diterpenes, their chemistry, distribution and biological activities. A review.

1978 • 93 citations

Carcinogens, identification and mechanisms of action

1979 • 82 citations

Kinetics and subcellular localization of specific [3H]phorbol 12, 13-dibutyrate binding by mouse brain.

1981 • 77 citations

Aryl hydrocarbon hydroxylase, epoxide hydrase, and 7,12-dimethylbenz(a)anthracene-produced skin tumorigenesis in the mouse.

1972 • 67 citations

Synergistic stimulation of early events and DNA synthesis by phorbol esters, polypeptide growth factors, and retinoids in cultured fibroblasts

1979 • 64 citations

Systemic two-stage carcinogenesis in the epithelium of the forestomach of mice using 7,12-dimethylbenz(a)anthracene as initiator and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.

1979 • 62 citations

Cocarcinogens of the diterpene ester type fromCroton flavens L. and esophageal cancer in Curaçao

1978 • 60 citations

Surface properties of phorbol esters and their interaction with lipid monolayers and bilayers.

1975 • 57 citations

Two-stage tumorigenesis of dermal melanocytes in the back skin of the Syrian golden hamster using systemic initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-O-tetradecanoylphorbol-13-acetate.

1980 • 55 citations

The effect of tumor-promoting phorbol diesters on terminal differentiation of cells in culture

1980 • 55 citations

On the active principles of croton oil

1970 • 47 citations

Reconstitution and purification by "transport specificity fractionation" of an ATP-dependent calcium transport component from synaptosome-derived vesicles.

1979 • 45 citations

Binding of [3H]12-O-tetradecanoylphorbol-13-acetate to intact human peripheral blood lymphocytes.

1980 • 41 citations

Variation with embryonic development and regional localization of specific [3H]phorbol 12,13-dibutyrate binding to brain.

1981 • 40 citations

Inflammation and tumor promotion: Selective protein induction in mouse skin by tumor promoters

1972 • 33 citations

Structure-activity relationships in chick embryo fibroblasts for phorbol-related diterpene esters showing anomalous activities in vivo.

1980 • 27 citations

Quantitative correlation between in vitro and in vivo activities of phorbol esters.

1979 • 26 citations

Investigations into the mode of action of the cocarcinogen 12-O-tetradecanoyl-phorbol-13-acetate using auxotrophic bacteria.

1977 • 25 citations

Different biological targets for resiniferatoxin and phorbol 12-myristate 13-acetate.

1980 • 25 citations

Specific binding of phorbol ester tumor promoters to mouse tissues and cultured cells.

1982 • 24 citations

Disturbances of early sea-urchin development by the tumor promoter TPA (phorbol ester)

1978 • 21 citations

Biological responsiveness to the phorbol esters and specific binding of [3H]phorbol 12,13-dibutyrate in the nematodeCaenorhabditis elegans, a manipulable genetic system

1982 • 17 citations

A brain membrane protein similar to the rat src gene product.

1981 • 11 citations

Welensali (Croton flavens): Folk uses and properties

1971 • 9 citations

SATURABLE ADENOSINE 5′‐TRIPHOSPHATE‐INDEPENDENT BINDING OF [³H]‐OUABAIN TO BRAIN AND CARDIAC TISSUE in vitro

1979 • 5 citations

Two-stage carcinogenesis in NMRI mice: intravaginal application of 7,12-dimethylbenz[a]anthracene as initiator followed by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter

1980 • 4 citations

Toxicity of several cancerigenic polycyclic hydrocarbons and other agents in AKR and C57BL-6 mice.

1967 • 3 citations

Phorbol related diterpene esters have similar structure-activity relations in Swiss 3T3 cells and chicken embryo fibroblasts

1980 • 3 citations