Structural and Lipid Biochemical Correlates of the Epidermal Permeability Barrier

Dermatology in General Medicine.

1987 • 4,066 citations

Permeability of the skin

1971 • 1,388 citations

Epidermal Lipids, Barrier Function, and Desquamation

1983 • 1,296 citations

Dermatology in General Medicine.

1988 • 1,130 citations

Drug permeation through human skin: Theory and invitro experimental measurement

1975 • 770 citations

The permeability barrier in mammalian epidermis.

1975 • 687 citations

Human stratum corneum lipids: characterization and regional variations

1983 • 664 citations

Skin Lipids: Their Biochemical Uniqueness

1974 • 576 citations

The Life of Birds

1964 • 543 citations

Ionic Calcium Reservoirs in Mammalian Epidermis: Ultrastructural Localization by Ion-Capture Cytochemistry

1985 • 440 citations

Transepidermal water loss: the signal for recovery of barrier structure and function.

1989 • 407 citations

Presence of Intact Intercellular Lipid Lamellae in the Upper Layers of the Stratum Corneum

1987 • 363 citations

Studies on Contact Sensitivity to Chromium in the Guinea Pig. The Role of Valence in the Formation of the Antigenic Determinant

1983 • 354 citations

Human epidermal lipids: characterization and modulations during differentiation

1983 • 350 citations

Structure of lamellar lipid domains and corneocyte envelopes of murine stratum corneum. An x-ray diffraction study

1988 • 348 citations

Evidence That the Corneocyte Has a Chemically Bound Lipid Envelope

1987 • 345 citations

Molecular models of the Intercellular Lipid Lamellae in Mammalian Stratum Corneum

1989 • 339 citations

Lipid content and lipid type as determinants of the epidermal permeability barrier.

1989 • 327 citations

Percutaneous Transport in Relation to Stratum Corneum Structure and Lipid Composition

1981 • 321 citations

ecology of whales and dolphins

1982 • 300 citations

Membrane Structures in Normal and Essential Fatty Acid-Deficient Stratum Corneum: Characterization by Ruthenium Tetroxide Staining and X-Ray Diffraction

1991 • 296 citations

The ecology of whales and dolphins

1982 • 291 citations

Mammalian Epidermal Barrier Layer Lipids: Composition and Influence on Structure

1977 • 284 citations

Lipid composition and metabolism in normal and diseased epidermis

1981 • 261 citations

Glycolipids in Mammalian Epidermis: Structure and Function in the Water Barrier

1982 • 246 citations

Lipid biophysics of water loss through the skin.

1990 • 246 citations

Relationship of epidermal lipogenesis to cutaneous barrier function.

1987 • 245 citations

Different populations of pig epidermal cells: isolation and lipid composition.

1975 • 235 citations

The permeability of keratinized and nonkeratinized oral epithelium to horseradish peroxidase

1973 • 231 citations

Localization and Composition of Lipids in Neonatal Mouse Stratum Granulosum and Stratum Corneum

1979 • 224 citations

The epidermal permeability barrier

1988 • 223 citations

The mammalian cutaneous permeability barrier: defective barrier function is essential fatty acid deficiency correlates with abnormal intercellular lipid deposition.

1978 • 215 citations

Selective Recovery of Deranged Water-Holding Properties by Stratum Corneum Lipids

1986 • 209 citations

De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements.

1985 • 208 citations

Membrane alterations during cornification of mammalian squamous epithelia: A freeze‐fracture, tracer, and thin‐section study

1977 • 202 citations

Stratum corneum lipids in disorders of cornification: increased cholesterol sulfate content of stratum corneum in recessive x-linked ichthyosis.

1981 • 197 citations

Stratum corneum lipids in disorders of cornification. Steroid sulfatase and cholesterol sulfate in normal desquamation and the pathogenesis of recessive X-linked ichthyosis.

1984 • 191 citations

Cholesterol synthesis is required for cutaneous barrier function in mice.

1990 • 191 citations

Lamellar Body-Enriched Fractions from Neonatal Mice: Preparative Techniques and Partial Characterization

1985 • 187 citations

Ultrastructural Localization of Calcium in Psoriatic and Normal Human Epidermis

1991 • 184 citations

Covalently bound ω-hydroxyacylsphingosine in the stratum corneum

1987 • 184 citations

Ordered Structure of the Stratum Corneum of Mammalian Skin

1969 • 178 citations

Epidermal Permeability Barrier: Transformation of Lamellar Granule-Disks into Intercellular Sheets by a Membrane-Fusion Process, a Freeze-Fracture Study

1986 • 177 citations

Membrane coating granules: The fate of the discharged lamellae

1976 • 174 citations

Preparation of Liposomes from Stratum Corneum Lipids

1986 • 174 citations

Alterations in membrane sugars during epidermal differentiation: visualization with lectins and role of glycosidases.

1983 • 167 citations

Sphingolipids of the Stratum Corneum and Lamellar Granules of Fetal Rat Epidemis

1984 • 150 citations

Lipid Composition and Acid Hydrolase Content of Lamellar Granules of Fetal Rat Epidermis

1985 • 149 citations

Effect of essential fatty acid deficiency on the epidermal sphingolipids of the rat

1983 • 149 citations

The Role of the Corneocyte Lipid Envelopes in Cohesion of the Stratum Corneum

1989 • 140 citations

THE MECHANISM OF WATER BINDING IN STRATUM CORNEUM

1968 • 138 citations

Research on dolphins

1986 • 137 citations

Odland-K�rper (Membrane Coating Granules, Keratinosomen) als epidermale Lysosomen

1967 • 136 citations

Isolation and Lipid Biochemical Characterization of Stratum Corneum Membrane Complexes: Implications for the Cutaneous Permeability Barrier

1982 • 136 citations

In Vitro and In Vivo Antistaphylococcal Activity of Human Stratum Corneum Lipids

1988 • 133 citations

Identification, isolation and characterization of epidermal lipids containing linoleic acid

1985 • 131 citations

Glycosphingolipids and Ceramides in Human and Pig Epidermis

1978 • 130 citations

Retinoid effects on epidermal structure, differentiation, and permeability.

1981 • 126 citations

In situ precipitation: a novel cytochemical technique for visualization of permeability pathways in mammalian stratum corneum.

1980 • 122 citations

Cytochemical and Biochemical Localization of Lipase and Sphingomyelinase Activity in Mammalian Epidermis

1986 • 121 citations

Structure and organization of mammalian stratum corneum

1971 • 112 citations

Isolation, barrier properties and lipid analysis of stratum compactum, a discrete region of the stratum corneum

1985 • 111 citations

Membrane Structural Alterations in Murine Stratum Corneum: Relationship to the Localization of Polar Lipids and Phospholipases

1988 • 108 citations

Lamellar granules in mammalian, avian, and reptilian epidermis

1980 • 103 citations

Desmosomal form, fate, and function in mammalian epidermis

1975 • 100 citations

Effect of Lipids on the Aggregation and Permeability of Human Stratum Corneum

1982 • 98 citations

Cell Shedding from Human Plantar Skin In Vitro: Evidence of Its Dependence on Endogenous Proteolysis

1988 • 95 citations

Electron microscopy of membrane-coating granules and a cell surface coat in keratinized and nonkeratinized human oral epithelium

1973 • 92 citations

Evidence that Cell Shedding from Plantar Stratum Corneum In Vitro Involves Endogenous Proteolysis of the Desmosomal Protein Desmoglein I

1990 • 92 citations

PERMEABILITY OF ORAL MUCOSA

1975 • 90 citations

The change in properties of the stratum corneum as a function of depth

1979 • 85 citations

Lysosomes And The Skin

1975 • 82 citations

Avian sebokeratocytes and marine mammal lipokeratinocytes: Structural, lipid biochemical, and functional considerations

1987 • 81 citations

The permeability of the intercellular space of the epidermis for low-molecular weight protein

1969 • 75 citations

Fine-structural observations on the formation and enzymatic activity of keratinosomes in mouse tongue filiform papillae

1970 • 75 citations

Avian epidermal differentiation: Role of lipids in permeability barrier formation

1986 • 74 citations

The Lamellar Granules of Epidermis

2015 • 70 citations

Stratum Corneum Lipid Liposomes: Calcium-Induced Transformation Into Lamellar Sheets

1987 • 69 citations

Skin pharmacokinetics

1988 • 69 citations

Cutaneous Resistance to Water-Vapor Diffusion in Pigeons and the Role of the Plumage

1985 • 67 citations

Water Permeation of Reaggregated Stratum Corneum with Model Lipids

1990 • 64 citations

Variations In Lipid Composition At Different Depths In The Cow Snout Epidermis

1970 • 62 citations

Variations in Lipids in Different Layers of Porcine Epidermis

1986 • 59 citations

X-ray Diffraction Analysis of Stratum Corneum Membrane Couplets

1983 • 58 citations

Lipokeratinocytes of the epidermis of a cetacean (Phocena phocena)

1986 • 57 citations

Avian epidermal differentiation II. Adaptive response of permeability barrier to water deprivation and replenishment

1989 • 55 citations

Intercellular Space in Normal Human Stratum Corneum

1966 • 54 citations

The lipid composition of porcine epidermis and oral epithelium

1986 • 54 citations

The Dependence of Detergent-Induced Cell Dissociation in Non-Palmo-Plantar Stratum Corneum on Endogenous Proteolysis

1990 • 53 citations

ULTRASTRUCTURAL CYTOCHEMISTRY OF THE EPIDERMIS

1977 • 49 citations

Structure Determination of Glucosylβ1-N-(ω-O-Linoleoyl)-Acylsphingosines of Human Epidermis

1989 • 48 citations

Cell shedding from human plantar skin in vitro: evidence that two different types of protein structures are degraded by a chymotrypsin-like enzyme

1990 • 48 citations

The Structure and Function of Spot Desmosomes

1981 • 47 citations

The skin of vertebrates

1980 • 45 citations

Lysosomes in oral epithelium: The ultrastructural localization of acid phosphatase and non-specific esterase in keratinized oral epithelium in man and rat

1970 • 45 citations

Membrane-Coating Granules Are Acidic Organelles Which Possess Proton Pumps

1989 • 44 citations

The epidermal permeability barrier. Comparison between in vivo and in vitro lipid structures.

1984 • 44 citations

Evidence for the holocrine nature of lipoid secretion by avian epidermal cells: A histochemical and fine structural study of rictus and the uropygial gland

1981 • 44 citations

Die epidermale Column�rstruktur

1971 • 42 citations

Glycoproteins modulate adhesion in terminally differentiated keratinocytes

1988 • 37 citations

Osmium Iodide Positive Granules in Spinous and Granular Layers of Guinea Pig Epidermis**From the Department of Anatomy, St. Mary's Hospital Medical School, (University of London), London, W.2, England.

1966 • 37 citations

Phospholipidgranula im verhornenden Oesophagusepithel

1966 • 36 citations

Observations on the Fine Structure of the Horny Layer in the Normal Human Epidermis

1964 • 33 citations

Localization of Lipid Microdomains and Thermal Phenomena in Murine Stratum Corneum and Isolated Membrane Complexes: An Electron Spin Resonance Study

1990 • 33 citations

Zinc iodide-osmium staining of membranecoating granules in keratinized and non-keratinized mammalian oral epithelium

1982 • 26 citations

Fine structural basis of the cutaneous water barrier in nestling Zebra Finches Poephila guttata

1988 • 25 citations

Cholesterol sulfate uptake and outflux in cultured human keratinocytes

1986 • 24 citations

A Unique Phospholipase A2 in Human Epidermis: Its Physiologic Function and Its Level in Certain Dermatoses

1988 • 24 citations

Isolation of lAmellar Bodies from Neonatal Mouse Epidermis by Selective Sequential Filtration

1983 • 23 citations

Immunochemical analysis of the distribution of the desmosomal protein desmoglein I in different layers of plantar epidermis.

1989 • 18 citations

Ultrastructural quantitation of desmosome and differentiation-related keratinocyte membrane antigen

1986 • 17 citations

β-Glucosidase activity in porcine epidermis

1989 • 17 citations

Freeze-Fracture Cytochemical Study of Membrane Systems in Human Epidermis Using Filipin As a Probe for Cholesterol

1985 • 14 citations

The ultrastructural demonstration of membrane-coating granules in rat oral epithelium using the periodic acid-bismuth technique

1977 • 10 citations

An ultrastructural study of the cere of the domestic pigeon (Columba livia).

1988 • 7 citations