Comparative Study of Human and Rat Mammary Tumorigenesis

The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells

1982 • 5,272 citations

Diseases of the Breast

1971 • 1,803 citations

Ackerman's surgical pathology

1974 • 1,070 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

Different intermediate-sized filaments distinguished by immunofluorescence microscopy.

1978 • 917 citations

Age at first birth and breast cancer risk.

1970 • 880 citations

An Atlas of Subgross Pathology of the Human Breast With Special Reference to Possible Precancerous Lesions<xref ref-type="fn" rid="fn2">2</xref>

1975 • 761 citations

Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations.

1985 • 735 citations

Diet, nutrition, and cancer

1976 • 678 citations

Differentiation of the mammary gland and susceptibility to carcinogenesis

1982 • 629 citations

Diversity of cytokeratins

1981 • 611 citations

Monoclonal antibodies to epithelium‐specific components of the human milk fat globule membrane: Production and reaction with cells in culture

1981 • 605 citations

Loss of basement membrane components by invasive tumors but not by their benign counterparts.

1983 • 497 citations

Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins.

1985 • 495 citations

The Mammary gland : development, regulation, and function

1987 • 396 citations

Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model.

1987 • 355 citations

<italic>N</italic>-Nitrosomethylurea as Mammary Gland Carcinogen in Rats

1975 • 354 citations

Biological and molecular bases of mammary carcinogenesis.

1987 • 341 citations

Induction and Extinction of Mammary Cancer

1962 • 331 citations

Differentiation antigens expressed by epithelial cells in the lactating breast are also detectable in breast cancers

1981 • 331 citations

Complexity of expression of antigenic determinants, recognized by monoclonal antibodies HMFG-1 and HMFG-2, in normal and malignant human mammary epithelial cells.

1983 • 331 citations

A new antigen on the epithelial membrane: its immunoperoxidase localisation in normal and neoplastic tissue.

1979 • 329 citations

Intermediate-sized filaments of the prekeratin type in myoepithelial cells.

1980 • 328 citations

Tumor invasion and metastases: role of the basement membrane. Warner-Lambert Parke-Davis Award lecture.

1984 • 321 citations

Methods and Results

1986 • 296 citations

COMPARATIVE STUDIES OF CANCEROUS VERSUS NONCANCEROUS BREASTS

1945 • 288 citations

Distribution of myoepithelial cells and basement membrane proteins in the normal breast and in benign and malignant breast diseases.

1982 • 285 citations

Developmental Stage of the Rat Mammary Gland as Determinant of Its Susceptibility to 7, 12-Dimethylbenz[<italic>a</italic>]anthracene<xref ref-type="fn" rid="FN2">2</xref>

1978 • 266 citations

A new small (40 kd) keratin filament protein made by some cultured human squamous cell carcinomas

1981 • 254 citations

Cancer Detection and Prevention

1976 • 245 citations

Surface differentiation antigens of human mammary epithelial cells carried on the human milk fat globule.

1977 • 244 citations

Influence of differentiation and cell kinetics on the susceptibility of the rat mammary gland to carcinogenesis.

1980 • 237 citations

FLUORIDATION OF DOMESTIC WATER.

1964 • 235 citations

Risk factors for endometrial cancer

1974 • 233 citations

Detection of a cytokeratin determinant common to diverse epithelial cells by a broadly cross-reacting monoclonal antibody.

1982 • 217 citations

Distribution of myoepithelial cells and basement membrane proteins in the resting, pregnant, lactating, and involuting rat mammary gland.

1982 • 213 citations

Early phases in the development of breast cancer

1969 • 212 citations

Pathology of tumors in laboratory animals

1980 • 211 citations

Breast Cancer Incidence Among Atomic Bomb Survivors, Hiroshima and Nagasaki, 1950–69

1977 • 202 citations

Development of the Human Mammary Gland

1987 • 199 citations

Angiogenesis as a marker of preneoplastic lesions of the human breast

1978 • 199 citations

Advances in Immunohistochemistry

1988 • 199 citations

COMPARATIVE STUDIES OF CANCEROUS VERSUS NONCANCEROUS BREASTS

1945 • 198 citations

Dietary fat and mammary cancer.

1968 • 197 citations

DNA Labeling Index and Structure of the Rat Mammary Gland as Determinants of Its Susceptibility to Carcinogenesis<xref ref-type="fn" rid="FN2">2</xref>

1978 • 194 citations

Dietary fat versus caloric content in initiation and promotion of 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats.

1984 • 193 citations

Cell proliferation in normal human breast ducts, fibroadenomas, and other ductal hyperplasias measured by nuclear labeling with tritiated thymidine

1977 • 191 citations

Monoclonal antibodies to the human mammary gland

1982 • 189 citations

Inhibition of carcinogenesis by retinoids.

1983 • 186 citations

Differences of expression of cytoskeletal proteins in cultured rat hepatocytes and hepatoma cells

1981 • 185 citations

Breast Cancer Risk From Low-Dose Exposures to Ionizing Radiation: Results of Parallel Analysis of Three Exposed Populations of Women

1980 • 179 citations

Characterization of cell surface antigens of human mammary epithelial cells with monoclonal antibodies prepared against human milk fat globule

1983 • 178 citations

The prevalence of carcinoma in situ in normal and cancer-associated breasts

1985 • 173 citations

Synergistic effect of vitamin E and selenium in the chemoprevention of mammary carcinogenesis in rats.

1983 • 171 citations

Inhibition of chemically induced mammary and colon tumor promotion by caloric restriction in rats fed increased dietary fat.

1987 • 170 citations

Susceptibility of the mammary gland to carcinogenesis: I Differentiation of the mammary gland as determinant of tumor incidence and type of lesion.

1979 • 170 citations

Inhibition of DMBA-induced mammary cancer by the monoterpene d-limonene

1984 • 167 citations

Susceptibility of the mammary gland to carcinogenesis. II. Pregnancy interruption as a risk factor in tumor incidence.

1980 • 159 citations

Dietary Fat and Mammary Cancer. I. Promoting Effects of Different Dietary Fats on <italic>N</italic>-Nitrosomethylurea-Induced Rat Mammary Tumorigenesis<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref><xref ref-type="fn" rid="FN3">4</xref>

1986 • 145 citations

Lifetime dose-response relationships for mammary tumor induction by a single administration of N-methyl-N-nitrosourea.

1981 • 145 citations

The Use of Antikeratin Antibodies in the Diagnosis of Human Neoplasms

1983 • 136 citations

Pathogenesis of Mammary Carcinomas Induced in Rats by 7, 12-Dimethylbenz[a]anthracene2

1977 • 132 citations

Identification of Myoepithelial Cells in Human and Rat-Breasts by Anti-Common Acute Lymphoblastic Leukemia Antigen Antibody A12

1986 • 127 citations

Diet, Nutrition, and Cancer

1982 • 126 citations

Ackerman's Surgical Pathology

1990 • 122 citations

Lactogenic Hormones, Fetal Nutrition, and Lactation

1975 • 116 citations

Circulating human mammary epithelial antigens in breast cancer.

1982 • 115 citations

The role of ovarian hormones in initiating the induction of mammary cancer in rats by polynuclear hydrocarbons.

1962 • 115 citations

Modulation of rat mammary carcinogenesis by indomethacin.

1985 • 112 citations

Comparative Anatomy, Pathology, and Roentgenology of the Breast

1960 • 110 citations

Chemoprevention of <italic>N</italic>-Nitroso-<italic>N</italic>-methylurea-Induced Mammary Cancers by Pretreatment with 17<italic>β</italic>-Estradiol and Progesterone<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>

1985 • 109 citations

Preneoplastic Lesions in the Human Breast

1976 • 108 citations

Stages of neoplastic transformation of human breast tissue as monitored by dissolution of basement membrane components. An immunoperoxidase study.

1981 • 106 citations

The evolution of carcinoma of the mamma

1941 • 105 citations

The distribution of keratin type intermediate filaments in human breast cancer

1981 • 105 citations

Dietary and Nutritional Influences on Cancer: A Review of Epidemiologic and Experimental Data

1989 • 100 citations

Genetic control of resistance to chemically induced mammary adenocarcinogenesis in the rat.

1986 • 97 citations

Human and Experimental Breast Cancer

1962 • 95 citations

Keratin Expression in the Mammary Gland

1987 • 94 citations

Susceptibility of the mammary gland to carcinogenesis. III. The cell of origin of rat mammary carcinoma.

1983 • 91 citations

Effects of different dietary fats on mammary carcinogenesis.

1983 • 90 citations

Estradiol stimulates synthesis of a major intracellular protein in a human breast cancer cell line (MCF-7)

1981 • 89 citations

Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy.

1982 • 87 citations

Keratins as markers of malignancy in mouse epidermal tumors

1980 • 86 citations

Expression of phenotypical changes by human breast epithelial cells treated with carcinogens in vitro.

1988 • 86 citations

Comparative effects of different animal and vegetable fats fed before and during carcinogen administration on mammary tumorigenesis, sexual maturation, and endocrine function in rats.

1986 • 84 citations

Immunohistochemical detection of laminin in 98 human breast carcinomas

1986 • 82 citations

Transplacental effects of diethylstilbestrol on mammary development and tumorigenesis in female ACI rats.

1987 • 78 citations

Advances in Immunohistochemistry

1989 • 77 citations

Selenium inhibition of chemical carcinogenesis.

1985 • 76 citations

Topographical arrangement of basement membrane proteins in lactating rat mammary gland: comparison of the distribution of type IV collagen, laminin, fibronectin, and Thy-1 at the ultrastructural level.

1983 • 75 citations

Influence of age and gland topography on cell kinetics of normal human breast tissue.

1987 • 75 citations

The Morphology of Hormone Induced Structural Changes in the Female Breast

1970 • 75 citations

Human and Experimental Breast Cancer

1962 • 74 citations

The synergism between radiation and estrogen in the production of mammary cancer in the rat.

1971 • 74 citations

Identification of mouse mammary epithelial cells by immunofluorescence with rabbit and guinea pig antikeratin antisera.

1981 • 71 citations

Effect of exercise on the induction of mammary carcinogenesis.

1988 • 69 citations

CRITICAL SIGNIFICANCE OF BREAST STRUCTURE IN THE INDUCTION OF MAMMARY CANCER IN THE RAT

1959 • 69 citations

Formation and removal of 7,12-dimethylbenz[a]anthracene -- nucleic acid adducts in rat mammary epithelial cells with different susceptibility to carcinogenesis

1981 • 69 citations

Neoplastic responses and correlated plasma prolactin levels in diethylstilbestrol-treated ACI and Sprague-Dawley rats.

1979 • 68 citations

Marker evolution during the development of the rat mammary gland: stem cells identified by markers and the role of myoepithelial cells.

1986 • 67 citations

Characterization of a laminin receptor from human breast carcinoma tissue

1984 • 67 citations

Inhibition of Benzo[<italic>a</italic>]pyrene-Induced Mammary Carcinogenesis by Retinyl Acetate<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1981 • 67 citations

Acquisition of angiogenic capacity and neoplastic transformation in the rat mammary gland.

1978 • 64 citations

Influence of dosage schedule on the biological characteristics of N-nitrosomethylurea-induced rat mammary tumors.

1980 • 63 citations

N-methyl-N-nitrosourea-induced rat mammary tumors. Hormone responsiveness but lack of spontaneous metastasis.

1981 • 62 citations

Keratin-Like Proteins in Normal and Neoplastic Cells of Human and Rat Mammary Gland as Revealed by Immunofluorescence Microscopy

1981 • 60 citations

Omega-3 Fatty Acids Inhibiting the Growth of a Transplantable Rat Mammary Adenocarcinoma

1987 • 59 citations

Development of the mammary gland of the rat: A study of normal, experimental and pathologic changes and their endocrine relationships

1937 • 59 citations

Development of Human Breast Cancer

1980 • 59 citations

Inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis by concomitant or postcarcinogen antioxidant exposure.

1984 • 59 citations

The Rat as Animal Model in Breast Cancer Research

1984 • 58 citations

Lactation and Menstrual Function as Related to Cancer of the Breast

1964 • 57 citations

Influence of diethylstilbestrol treatment on prolactin cells of female ACI and Sprague-Dawley rats.

1979 • 57 citations

<italic>N</italic>-Nitroso-<italic>N</italic>-methylurea-Induced Mammary Carcinogenesis: Effect of Pregnancy on Preneoplastic Cells<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 56 citations

Atypical epithelial hyperplasia associated with breast cancer and fibrocystic disease

1969 • 56 citations

Lactogenic hormones, fetal nutrition, and lactation

1974 • 55 citations

An autopsy study of the adult human breast

1962 • 55 citations

Studies on Radiation-Induced Mammary Gland Neoplasia in the Rat: III. Relation of the Neoplastic Response to Dose of Total-Body Radiation

1960 • 55 citations

Actin-Rich (myoepithelial) cells in ductal carcinoma-in-situ of the breast

1980 • 55 citations

Comparison between the effects of dietary fat level and of calorie intake on methylnitrosourea‐induced mammary carcinogenesis in female sd rats

1987 • 54 citations

An immunocytochemical study of the distribution of epithelial membrane antigen in normal and disordered squamous epithelium.

1982 • 54 citations

Biological Effects of Low-level Radiation

1985 • 53 citations

Inheritance of a genetic factor from the Copenhagen rat and the suppression of chemically induced mammary adenocarcinogenesis.

1988 • 52 citations

Mammary Carcinogenesis in Rats in Relation to Age at Time of <italic>N</italic>-Nitroso-<italic>N</italic>-methylurea Administration<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref><xref ref-type="fn" rid="FN4">4</xref>

1983 • 50 citations

Immunofluorescence detection of casein in human mammary dysplastic and neoplastic tissues

1975 • 49 citations

The Combined Effects of Dietary Protein and Fat on 7,12-Dimethylbenz(a)anthracene-Induced Breast Cancer in Rats

1984 • 49 citations

Comparison of the actions of the antiprogestin mifepristone (RU486), the progestin megestrol acetate, the LHRH analog buserelin, and ovariectomy in treatment of rat mammary tumors.

1987 • 49 citations

Induction of mammary gland carcinomas by the subcutaneous injection of 1-methyl-1-nitrosourea.

1983 • 48 citations

Effect of Duration of High Fat Intake on Enhancement of Mammary Carcinogenesis in Rats<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 48 citations

Effect of ovarian hormones on the induction of 1-methyl-1-nitrosourea-induced mammary cancer

1983 • 46 citations

7,12-Dimethylbenz[<italic>a</italic>]anthracene-Induced DNA Binding and Repair Synthesis in Susceptible and Nonsusceptible Mammary Epithelial Cells in Culture<xref ref-type="fn" rid="FN2">2</xref>

1981 • 46 citations

Retinoid-tamoxifen interaction in mammary cancer chemoprevention

1986 • 45 citations

Suppression by pregnancy of chemically induced preneoplastic cells of the rat mammary gland.

1986 • 45 citations

Classification of Neoplastic and Nonneoplastic Lesions of the Rat Mammary Gland

1989 • 45 citations

Effect of concentration of D,L-2-difluoromethylornithine on murine mammary carcinogenesis.

1985 • 43 citations

Relationship of Fibrocystic Disease to Carcinoma of the Breast

1965 • 43 citations

Modification by antioxidants and p, p'-diaminodiphenylmethane of 7, 12-dimethylbenz[a]anthracene-induced carcinogenesis of the mammary gland and ear duct in CD rats

1986 • 41 citations

Basis of Cellular Autonomy in the Subsceptibility to Carcinogenesis

1983 • 40 citations

The demonstration of α lactalbumin in human breast carcinomas

1979 • 40 citations

Effect of D,L-2-difluoromethylornithine and endocrine manipulation on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea

1986 • 39 citations

Influence of delayed administration of retinyl acetate on mammary carcinogenesis.

1982 • 39 citations

Relationship of metabolic activation of N-hydroxy-N-acylarylamines to biological response in the liver and mammary gland of the female CD rat.

1981 • 37 citations

Immunocytochemistry in Tumor Diagnosis

1985 • 37 citations

Results of fractionation and protraction of total-body radiation on rat mammary neoplasia.

1966 • 36 citations

Transplacental action of diethylstilbestrol on mammary carcinogenesis in female rats given one or two doses of 7,12-dimethylbenz(a)anthracene.

1983 • 36 citations

Influence of caffeine and/or coffee consumption on the initiation and promotion phases of 7,12-dimethylbenz(a)anthracene-induced rat mammary gland tumorigenesis.

1988 • 36 citations

Interaction of Vitamin C and Selenium Supplementation in the Modification of Mammary Carcinogenesis in Rats<xref ref-type="fn" rid="FN1">2</xref>

1986 • 35 citations

Rat Differences in Mammary Tumor Induction With Estrogen and Neutron Radiation<xref ref-type="fn" rid="FN2">2</xref>

1978 • 35 citations

Diagnostic value of intermediate filament antibodies in clinical cytology

1984 • 34 citations

Effects of Dietary Protein, Fat and Energy Intake during an Initiation Phase Study of 7,12-Dimethylbenz[a]anthracene-Induced Breast Cancer in Rats

1986 • 32 citations

Effects of high dietary fat on the growth and development of ovarian-independent carcinogen-induced mammary tumors in rats.

1986 • 31 citations

In vitro synthesis of immunoglobulins and other proteins by dysplastic and neoplastic human mammary tissues.

1976 • 30 citations

Intraductal epithelial proliferation in the human breast-a comparative study.

1962 • 30 citations

Mammary Carcinogenesis in Different Rat Strains after Irradiation and Hormone Administration

1987 • 30 citations

Mammary Carcinogenic Effect of Low-Dose Fission Radiation in Wistar/Furth Rats and Its Dependency on Prolactin2

1980 • 30 citations

Influence of caffeine consumption on carcinomatous and normal mammary gland development in mice.

1988 • 29 citations

Influence of Dietary Retinyl Acetate on Normal Rat Mammary Gland Development and on the Enhancement of 7,12-Dimethylbenz[<italic>a</italic>]anthracene-Induced Rat Mammary Tumorigenesis by High Levels of Dietary Fat<xref ref-type="fn" rid="FN2">2</xref>

1986 • 29 citations

Myoepithelial Cells in Lobular Carcinoma in Situ of the Breast: A Parallel Immunocytochemical and Ultrastructural Study

1981 • 29 citations

Immunohistochemical study of the expression of human milk fat globule membrane glycoprotein 70.

1984 • 29 citations

Carcinoma-specific keratin polypeptide patterns in keratinizing epithelia of rodents: independence of species-and tissue specific variations

1981 • 28 citations

Similarities of antisera to casein and epithelial membrane antigen

1982 • 27 citations

Influence of the estrous cycle during carcinogen exposure on nitrosomethylurea-induced rat mammary carcinoma.

1981 • 26 citations

Studies on radiation-induced mammary gland neoplasia in the rat. 5. Induction by localized irradiation.

1960 • 25 citations

Estrous cycle modification of rat mammary tumor induction by a single dose of N-methyl-N-nitrosourea.

1985 • 25 citations

Desquamative and dysgentic epithelial hyperplasias in the breast: Their situation and characteristics: Their likeness to lesions induced by tar

1926 • 25 citations

Mammary tumorigenesis in rats fed diets high in lard

1986 • 25 citations

Influence of caffeine consumption on 7,12-dimethylbenz(a)anthracene-induced mammary gland tumorigenesis in female rats fed a chemically defined diet containing standard and high levels of unsaturated fat.

1988 • 24 citations

Tumours of the breast. Their pathology, symptoms, diagnosis and treatment

1932 • 24 citations

Prolactin concentration in plasma and susceptibility to mammary tumors in female rats from different strains treated chronically with estradiol-17β

1984 • 24 citations

Development of the Female Breast

1974 • 23 citations

Absence of an effect of dietary corn oil content on plasma prolactin, progesterone, and 17 beta-estradiol in female Sprague-Dawley rats.

1984 • 23 citations

Anticarcinogenic activity of quinacrine in the rat mammary gland

1988 • 23 citations

Relation of fibroadenomatosis (chronic mastitis) to cancer of the breast

1954 • 22 citations

The biochemical and immunocytochemical characterisation of an antigen on the membrane of basal cells of the epidermis

1985 • 21 citations

Abnormal deposition of basement membrane and connective tissue components in dimethylbenzanthracene-induced rat mammary tumours: an immunocytochemical and ultrastructural study

1985 • 21 citations

Dietary fat and DMBA mammary carcinogenesis in rats.

1981 • 20 citations

A stereomicroscopic study of the mastopathic human breast

1970 • 20 citations

Actuarial analysis of the hazard for mammary carcinogenesis in different rat strains after X- and neutron irradiation

1986 • 19 citations

Neoplasms in Rats Exposed to Single-Dose Total-Body X Radiation<xref ref-type="fn" rid="fn1">2</xref>

1953 • 19 citations

The identification of ‘casein’ in human breast cancer

1979 • 18 citations

Effects of dietary fat on age-dependent sensitivity to mammary carcinogenesis

1983 • 17 citations

Studies on Radiation-Induced Mammary Gland Neoplasia in the Rat: V. Induction by Localized Irradiation

1960 • 16 citations

Neoplastic Diseases

1979 • 15 citations

Immunocytochemical Markers in Breast Cancer

1985 • 15 citations

Dimethylbenzanthracene mammary tumorigenesis in sprague-dawley rats fed diets differing in content of beef tallow or rapeseed oil

1983 • 14 citations

Synergistic interactions of various doses of diethylstilbestrol and x-irradiation on mammary neoplasia in female ACI rats.

1980 • 14 citations

Radiation-induced mammary carcinogenesis in virgin, pregnant, lactating, and postlactating rats.

1982 • 14 citations

Effects of X-irradiation, ovariohysterectomy and estradiol-17β on incidence, benign/malignant ratio and multiplicity of rat mammary neoplasms—A preliminary report

1986 • 12 citations

Differentiation and growth in the human breast parenchyma

1989 • 12 citations

A stereomicroscopic study of the mastopathic human breast

1970 • 12 citations

The gene transfer-misrepair hypothesis of radiation carcinogenesis tested for induction of mammary tumours in rats

1986 • 11 citations

Assessment of interaction among three carcinogens on rat mammary carcinogenesis in a factorially designed experiment.

1987 • 8 citations

Na⁺K⁺ Dependent Atpase as a Specific Marker for Myoepithelial Cells: An Ultrastructural Study.

1975 • 4 citations

Enhancement of 7,12-Dimethylbenz(a)anthracene Mammary Carcinogenesis by a High Lard Diet

1986 • 4 citations

Deleted Work

1955 • 0 citations