Expression analysis of the individual bovine β-,αs2- and κ-casein genes in transgenic mice

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

Prolactin regulation of beta-casein gene expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell line.

1988 • 513 citations

Genomic analysis of the major bovine milk protein genes

1990 • 287 citations

Beta-casein gene promoter activity is regulated by the hormone-mediated relief of transcriptional repression and a mammary-gland-specific nuclear factor.

1991 • 284 citations

A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice

1993 • 275 citations

Prolactin and glucocorticoid hormones synergistically induce expression of transfected rat beta-casein gene promoter constructs in a mammary epithelial cell line.

1989 • 257 citations

Extracellular matrix and hormones transcriptionally regulate bovine beta-casein 5' sequences in stably transfected mouse mammary cells.

1990 • 217 citations

Transcriptional regulation of multigene loci: multilevel control

1993 • 187 citations

A novel transcriptional enhancer is involved in the prolactin- and extracellular matrix-dependent regulation of beta-casein gene expression.

1992 • 187 citations

Isolation and characterization of the bovine k‐casein gene

1988 • 165 citations

Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice.

1993 • 141 citations

The nuclear factor YY1 participates in repression of the beta-casein gene promoter in mammary epithelial cells and is counteracted by mammary gland factor during lactogenic hormone induction.

1994 • 141 citations

Characterization and Cloning of the mRNAs Specific for the Lactating Mouse Mammary Gland

1982 • 134 citations

Rabbit β-Casein Promoter Directs Secretion of Human Interleukin-2 into the Milk of Transgenic Rabbits

1990 • 120 citations

Evolution of the casein multigene family: conserved sequences in the 5′ flanking and exon regions

1986 • 110 citations

Bovine AlphaS1-Casein Gene Sequences Direct High Level Expression of Active Human Urokinase in Mouse Milk

1990 • 106 citations

Cloning of the goat β-casein-encoding gene and expression in transgenic mice

1992 • 105 citations

Bovine lactoferrin mRNA: Sequence, analysis, and expression in the mammary gland

1991 • 105 citations

Tissue-specific expression of the rat β-casein gene in transgenic mice

1988 • 102 citations

Prolactin and Glucocorticoid Hormones Control Transcription of the β-Casein Gene by Kinetically Distinct Mechanisms

1990 • 92 citations

Localization of the casein gene family to a single mouse chromosome.

1982 • 88 citations

Both cell substratum regulation and hormonal regulation of milk protein gene expression are exerted primarily at the posttranscriptional level.

1988 • 83 citations

Localization of the α-S2-casein gene (CASAS2) to the homoeologous cattle, sheep, and goat chromosomes 4 by in situ hybridization

1993 • 82 citations

The complete sequence of the gene encoding bovine α2-casein

1993 • 73 citations

Mammary gland-specific nuclear factor activity is positively regulated by lactogenic hormones and negatively by milk stasis.

1992 • 72 citations

Differential regulation of rat beta-casein-chloramphenicol acetyltransferase fusion gene expression in transgenic mice.

1989 • 56 citations

Expression of human lysozyme mRNA in the mammary gland of transgenic mice

1994 • 56 citations

High expression of the caprine β‐casein gene in transgenic mice

1992 • 55 citations

Functions of milk protein gene 5′ flanking regions on human growth hormone gene

1994 • 53 citations

β-Casein Gene Promoter Activity Is Regulated by the Hormone- Mediated Relief of Transcriptional Repression and a MammaryGland-Specific Nuclear Factor

1991 • 52 citations

Multiple ocatamer binding sites in the promoter region of the bovineαs2-Casein gene

1992 • 52 citations

A pregnancy-specific mammary nuclear factor involved in the repression of the mouse beta-casein gene transcription by progesterone.

1992 • 49 citations

β-Casein mRNA Sequesters a Single-Stranded Nucleic Acid-Binding Protein Which Negatively Regulates the β-Casein Gene Promoter

1994 • 43 citations

A 230kb cosmid walk in the Duchenne muscular dystrophy gene: detection of a conserved sequence and of a possible deletion prone region

1987 • 39 citations

Efficient generation of functional transgenes by homologous recombination in murine zygotes

1992 • 35 citations

Molecular Cloning of Mouse Mammary Gland ϰ-Casein: Comparison With Rat ϰ-Casein and Rat and Human γ-Fibrinogen

1985 • 32 citations

Regulation of expression of genes for milk proteins.

1991 • 32 citations

Both Cell Substratum Regulation and Hormonal Regulation of Milk Protein Gene Expression Are Exerted Primarily at the Posttranscriptional Level

1988 • 29 citations

Progesterone regulation of a pregnancy-specific transcription repressor to beta-casein gene promoter in mouse mammary gland.

1992 • 22 citations

Differential Regulation of Rat β-Casein–Chloramphenicol Acetyltransferase Fusion Gene Expression in Transgenic Mice

1989 • 17 citations

Analysis of milk protein gene expression in transgenic mice.

1989 • 16 citations