Role of the Renin-Angiotensin System in Renal Hypertension. An Experimental Approach

STUDIES ON EXPERIMENTAL HYPERTENSION

1934 • 2,092 citations

On the local reactions of the arterial wall to changes of internal pressure

1902 • 1,485 citations

Arterial pressure regulation

1972 • 1,044 citations

Circulation: Overall Regulation

1972 • 858 citations

Eine einfache colorimetrische Methode zur Inulinbestimmung f�r Nieren-Clearance-Untersuchungen bei Stoffwechselgesunden und Diabetikern

1955 • 798 citations

Niere und Kreislauf¹

1898 • 761 citations

Control of renin release.

1967 • 526 citations

A CRYSTALLINE PRESSOR SUBSTANCE (ANGIOTONIN) RESULTING FROM THE REACTION BETWEEN RENIN AND RENIN-ACTIVATOR

1940 • 427 citations

Interrelationship of Electrolytes, Juxtaglomerular Cells and Hypertension

1960 • 383 citations

The substance causing renal hypertension

1940 • 360 citations

Die Natriumkonzentration an den Macula densa-Zellen als regulierender Faktor f�r das Glomerulumfiltrat (Mikropunktionsversuche)

1965 • 359 citations

ANGIOTENSIN AND RENIN IN RAT AND DOG BRAIN

1971 • 352 citations

Hypertension of Renal Origin: Evidence for Two Different Mechanisms

1971 • 338 citations

Renin in dog brain

1971 • 301 citations

Brief Reviews : A Systems Analysis Approach to Understanding Long-Range Arterial Blood Pressure Control and Hypertension

1974 • 298 citations

Role of the Pressor Action of Angiotensin IIin Experimental Hypertension

1971 • 297 citations

Effect of Pulse Pressure and Mean Arterial Pressure Modification on Renal Hemodynamics and Electrolyte and Water Excretion

1951 • 294 citations

Angiotensin-Sodium Interaction in Blood Pressure Maintenance of Renal Hypertensive and Normotensive Rats

1973 • 288 citations

Control of Renin Secretion

1964 • 265 citations

RENAL CHANGES IN MALIGNANT HYPERTENSION

1939 • 249 citations

STUDIES ON RENAL JUXTAGLOMERULAR CELLS

1953 • 239 citations

HYPERTENSION EXPLAINED BY STARLING'S THEORY OF CIRCULATORY HOMŒOSTASIS

1963 • 218 citations

The control of renin release

1973 • 210 citations

Regulation of superficial nephron filtration rate by tubulo-glomerular feedback

1970 • 199 citations

Angiotensin II Vascular Receptors: Their Avidity in Relationship to Sodium Balance, the Autonomic Nervous System, and Hypertension

1972 • 197 citations

RENIN-ANGIOTENSIN SYSTEM, ALDOSTERONE, AND SODIUM BALANCE.

1965 • 192 citations

Silver Impregnation Methods for Electron Microscopy

1961 • 176 citations

A plethysmographic method for measuring systolic blood pressure in the intact rat

1938 • 175 citations

THE PRESENCE OF RENIN ACTIVITY IN BLOOD VESSEL WALLS

1964 • 159 citations

THE VICIOUS CIRCLE IN CHRONIC BRIGHT'S DISEASE. EXPERIMENTAL EVIDENCE FROM THE HYPERTENSIVE RAT

1941 • 150 citations

Synthesis and Pharmacology of the Octapeptide Angiotonin

1957 • 146 citations

Renin, Aldosterone, Body Fluid Volumes, and the Baroreceptor Reflex in the Development and Reversal of Goldblatt Hypertension in Conscious Dogs

1974 • 142 citations

THE PURIFICATION OF HYPERTENSIN I

1954 • 137 citations

Inhibition of Angiotensin Conversion in Experimental Renovascular Hypertension

1972 • 127 citations

Localization of Renin in Juxtaglomerular Cells of Rabbit and Dog Through the Use of the Fluorescent-Antibody Technique

1961 • 126 citations

PATHOGENESIS OF ARTERIAL HYPERTENSION

1949 • 126 citations

Existence of an Endocrine Gland in the Media of the Renal Arterioles

1939 • 124 citations

Mechanism of renin release following furosemide diuresis in rabbit

1968 • 115 citations

The Response of Blood Pressure to Infusion of Angiotensin II: Relation to Plasma Concentrations of Renin and Angiotensin II

1972 • 113 citations

POTENTIAL SCREENING TEST FOR DETECTION OF OVERACTIVITY OF RENIN-ANGIOTENSIN SYSTEM

1971 • 112 citations

RENAL CHANGES IN MALIGNANT HYPERTENSION

1939 • 108 citations

Die Diurese bei arteriellen Drucksteigerungen

1962 • 105 citations

The effect of nephrectomy and adrenalectomy upon the blood pressure in hypertensive and normotensive rats.

1951 • 103 citations

Inhibition of angiotensin conversion and prevention of renal hypertension

1975 • 103 citations

A RENIN-LIKE SUBSTANCE IN THE PLACENTA AND UTERUS OF THE RABBIT

1964 • 100 citations

STUDIES ON RENAL JUXTAGLOMERULAR CELLS

1955 • 100 citations

Whole-Body Circulatory Autoregulation and Hypertension

1971 • 100 citations

EFFECT OF ANGIOTENSIN AND OF FRUSEMIDE ON PLASMA ALDOSTERONE, CORTICOSTERONE, CORTISOL, AND RENIN IN MAN

1965 • 95 citations

The location of renin in the rabbit kidney

1959 • 94 citations

Activation of renin in the single juxtaglomerular apparatus by sodium chloride in the tubular fluid at the macula densa.

1972 • 91 citations

Contrasting exchangeable sodium in rats with different types of Goldblatt hypertension

1969 • 88 citations

A New, Long-Lasting Competitive Inhibitor of Angiotensin

1972 • 88 citations

A Specific Competitive Inhibitor of Angiotensin II

1970 • 87 citations

Structure-Activity Relationship in Angiotensin II Analogs

1974 • 85 citations

Angiotensin II: Important Role in the Maintenance of Arterial Blood Pressure

1973 • 83 citations

Rabbit uterus as a source of renin

1967 • 82 citations

Synthesis of some analogs of angiotensin II as specific antagonists of the parent hormone

1972 • 76 citations

Der Blutdruck bei experimenteller Urämie und partieller Nierenausscheidung

1930 • 75 citations

Circulatory control in hypertension.

1970 • 71 citations

THE ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN BLOOD PRESSURE REGULATION AND KIDNEY FUNCTION.

1964 • 71 citations

Angiotensin analogs: the influence of sarcosine substituted in position 1.

1974 • 71 citations

THE PURIFICATION OF HYPERTENSIN II

1956 • 70 citations

Fluid reabsorption in Henle's loop and urinary excretion of sodium and water in normal rats and rats with chronic hypertension

1970 • 68 citations

Use of angiotensin II antagonists in experimental hypertension.

1973 • 66 citations

Effects of a specific competitive antagonist of angiotensin II on arterial pressure and adrenal steroid secretion in dogs.

1973 • 66 citations

Antihypertensive effect of an isolated phospholipid

1968 • 65 citations

Whole-Body Circulatory Autoregulation and Hypertension

1971 • 65 citations

Renin activity in aortic tissue of rats

1969 • 65 citations

Analogs of angiotensin II. II. Mechanism of receptor interaction

1970 • 64 citations

Brief Reviews : Agents Which Block the Action of the Renin-Angiotensin System

1974 • 64 citations

The Renin-Angiotensin System and Aldosterone Secretion during Sodium Depletion in the Rat

1974 • 63 citations

Studies on the role of angiotensin in experimental renovascular hypertension: an immunologic approach

1969 • 61 citations

Renin Activity Content in Various Tissues of Dogs Under Different Physiopathological States

1970 • 59 citations

Bio-assay of circulating renin-like pressor material by isovolemic cross circulation

1963 • 56 citations

The role of the kidney in acute and chronic hypertension following renal artery constriction in the rabbit.

1945 • 55 citations

Changes in Renin Content in Kidneys of Renal Hypertensive Rats

1962 • 54 citations

Norepinephrine and renin content in arterial tissue from different vascular beds

1969 • 51 citations

Natrium- und Wasserresorption in den verschiedenen Abschnitten des Nephrons beim experimentellen renalen Hochdruck der Ratte

1968 • 46 citations

Quantitative assay and disappearance rate of circulating renin

1964 • 45 citations

Biological significance of renin angiotensin immunization.

1970 • 44 citations

Renal Hypertension in Rabbits Immunized with Angiotensin - II

1970 • 44 citations

Synthese von Hypertensin‐II‐peptiden

1957 • 43 citations

A Renin‐Like Pressor Substance Found in the Placenta of the Cat

1960 • 43 citations

Function of juxtamedullary nephrons in normotensive and chronically hypertensive rats

1969 • 43 citations

Renin-angiotensin activity in hypertensive rats with a single ischemic kidney.

1971 • 41 citations

Intrarenal Action of Angiotensin

1974 • 40 citations

�ber einen reninartigen Wirkstoff in Arterienextrakten

1956 • 40 citations

Renin release and renin-substrate reaction in the isolated perfused rabbit kidney

1972 • 37 citations

Generation of Angiotensin II at Peripheral Vascular Level: Studies Using Angiotensin II Antisera

1973 • 37 citations

Changes of plasma renin concentration during pressor infusions of renin in the conscious dog: the influence of dietary sodium intake.

1968 • 37 citations

Plasma renin activity in hypertensive rats after treatment with renin preinhibitor

1969 • 36 citations

Die Blutentnahme aus dem retroorbitalen Venenplexus

1955 • 35 citations

Differential Effects of an Angiotensin II Analogue on Pressor and Adrenal Receptors in the Rabbit

1974 • 34 citations

Renovascular Hypertension in Rats Immunized with Angiotensin II

1972 • 34 citations

Rapid Demonstration of Juxtaglomerular Granules in Mammals and Birds

1966 • 34 citations

Renal Hypertension in Rabbits immunized with Angiotensin

1969 • 33 citations

Possibility that Angiotensin Resulting from Unilateral Kidney Disease Affects Contralateral Renal Function

1971 • 32 citations

The effect of antirenin on the blood pressure of the rat with exprimental renal hypertension.

1969 • 31 citations

Effect of rabbit antibodies against angiotensin‐II on the pressor response to angiotensin‐II and renal hypertension in the rat

1968 • 31 citations

Vascular and adrenocortical responses to a specific antagonist of angiotensin II

1975 • 31 citations

RENIN AND HYPERTENSION

1966 • 31 citations

Antagonism of peripheral and central effects of angiotensin II by (1-sarcosine, 8-isoleucine)angiotensin II.

1973 • 31 citations

Sodium excretion in goldblatt hypertension

1972 • 29 citations

Action of Angiotensin Antagonists and Antiserum upon the Pressor Response to Renin: Further Evidence for the Local Generation of Angiotensin II

1974 • 29 citations

The Role of the Renin—Angiotensin—Aldosterone System in Cardiovascular Homeostasis in Normal Man

1974 • 28 citations

ROLE OF THE RENIN‐SYSTEM IN NORMO‐ AND HYPERTENSION

1973 • 28 citations

Arterial and Urinary Renin Activity

1972 • 28 citations

Production of Renin by Human Juxtaglomerular Cells in Vitro

1966 • 28 citations

Location of renin in kidneys and extrarenal tissues.

1967 • 27 citations

Renal blood flow and perfusion pressure before and after development of renal hypertension

1973 • 27 citations

The Pressor and Myotropic Effects and the Antagonistic Properties of Several Analogues of Angiotensin II

1972 • 25 citations

Role of angiotensin II in experimental renal hypertension in the rabbit

1975 • 25 citations

The effect of intravenous antirenin injection on chronic experimental and acute renin-induced hypertension in dogs.

1970 • 23 citations

Mechanism of the fall in blood pressure after ‘unclamping’ in rats with Goldblatt-type hypertension

1970 • 23 citations

Impaired Autoregulation of Blood Flow and Glomerular Filtration Rate in the Isolated Dog Kidney Depleted of Renin

1974 • 22 citations

A potent competitive antagonist of angiotensin II

1972 • 22 citations

�ber das renin�hnliche Enzym der Glandula submaxillaris der wei�en Maus

1962 • 20 citations

Anreicherung und Immunspezifität des Isorenins der Glandula submaxillaris der Maus

1968 • 19 citations

Reductions in Blood Pressures of Renal Hypertensive Dogs by Hog Renin.

1941 • 18 citations

Angiotensin

1974 • 18 citations

Renin and Hypertension. A Modern Synthesis.

1970 • 18 citations

Subcellular Localization of Cerebral Renin-Like Activity

1972 • 17 citations

A Fluorescent Antibody Study of Juxtaglomerular Cells Using the Freeze-Substitution Technique

1970 • 17 citations

Function of the renin-angiotensin system in the isolated perfused rat kidney

1974 • 17 citations

Role of angiotensin in normal blood pressure regulation

1969 • 13 citations

Renin secretion in the earliest stage of goldblatt-type hypertension in rats

1972 • 12 citations

Sodium Retention Versus Renin–Angiotensin System In Experimental Renal Hypertension

1973 • 11 citations

Nature of the pressor substance in rabbit placenta

1967 • 11 citations

Renal hypertension and angiotensin antibodies

1972 • 11 citations

Contrôle de la sécrétion de rénine

1970 • 10 citations

Unterschiedliche Beeinflussung der Blutdruckwirkung von Renin und Angiotensin durch Aminopeptidase

1966 • 10 citations

ChemInform Abstract: AGONIST AND ANTAGONIST RELATIONSHIPS IN 1‐ AND 8‐SUBSTITUTED ANALOGS OF ANGIOTENSIN II

1975 • 10 citations

Regulation der Reninsekretion bei Aldosteronmangel und bei Aldosteronismus

1968 • 10 citations

Das Verhalten der Plasmareninkonzentration nach akuter Natriurese und nach Orthostase bei Gesunden und Hypertonikern

1970 • 10 citations

Plasma renin activity in renal hypertensive rats

1972 • 9 citations

Gesteigerter Na-Umsatz bei renal hypertonischen Ratten

1970 • 8 citations

Plasma renin concentration in conscious rabbits during pressor infusions of renin.

1967 • 8 citations

Effet de l'ablation partielle ou totale du tissu rénal sur l'hypertension rénovasculaire chez le rat

1969 • 7 citations

EXPERIMENTAL RENAL AND RENOPRIVAL HYPERTENSION

1971 • 7 citations

Disturbances of the control of renin secretion in chronic one-kidney-goldblatt hypertension in the rat

1974 • 6 citations

Beschleunigte Natriurese und Diurese beim Hochdruck: Folge einer Resorptionshemmung in der Henleschen Schleife

1971 • 6 citations

Mikropunktionsuntersuchung der geklammerten Niere bei einseitig nephrektomierten Ratten mit experimentellem renalen Hochdruck

1969 • 6 citations

Urinary Acidification and Electrolyte Excretion in Renal Hypertensive Rats

1970 • 5 citations

Effect of Removal of a Clipped Kidney or Cessation of Renin Administration on Hypertension.

1965 • 4 citations

Das Blutvolumen in den verschiedenen Stadien der tierexperimentellen renovasculären Hypertonie

1969 • 4 citations

Verhalten des Renin-�hnlichen Prinzips in der Speicheldr�se der wei�en Maus unter verschiedenen Bedingungen

1966 • 4 citations

INDUCED CHANGES IN THE ANTIGENICITY OF RENIN AND THE PRODUCTION OF ANTIRENIN TO HOMOLOGOUS RENIN AND TO HUMAN RENIN.

1964 • 4 citations

Statischer Druck, Blutvolumen und zentralvenöser Druck bei renovaskulärer Hypertonie

1971 • 4 citations

Société Suisse de Néphrologie

1974 • 3 citations

The Effect of Nephrectomy and of Renomedullary Extracts on the Blood Pressure of Experimentally Hypertensive Rabbits

1972 • 2 citations

Deleted Work

1955 • 0 citations