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Sexual Maturation and Differentiation: The Role of the Gonadal Steroids

Data up to Jan 2025

Published1978
Citations63
References87

Total Citations Per Year

Abstract

References (87)

Evidence for a morphological sex difference within the medial preoptic area of the rat brain

1978 • 1,207 citations

The Formation of Estrogens by Central Neuroendocrine Tissues

1975 • 794 citations

Changes with Age in Levels of Serum Gonadotropins, Prolactin, and Gonadal Steroids in Prepubertal Male and Female Rats

1975 • 730 citations

Sexual dimorphism in the neurophil of the preoptic area of the rat and its dependence on neonatal androgen

1973 • 583 citations

Aromatization: Important for sexual differentiation of the neonatal rat brain

1977 • 447 citations

Hormonal factors in the sex differentiation of the mammalian foetus

1970 • 376 citations

Sex steroids and the development of the newborn mouse hypothalamus and preoptic areain vitro: implications for sexual differentiation

1976 • 372 citations

ANDROGEN CONCENTRATIONS IN PLASMA AND TESTIS OF DEVELOPING RATS

1968 • 282 citations

Sex differences in dendritic patterns in hamster preoptic area

1977 • 268 citations

Rat Estradiol Binding Plasma Protein (EBP)

1971 • 255 citations

COMPARATIVE ULTRASTRUCTURAL AND HISTOCHEMICAL STUDIES OF THE INTERSTITIAL CELLS OF THE RAT TESTIS DURING FETAL AND POSTNATAL DEVELOPMENT

1972 • 233 citations

Reproductive Behavior

1974 • 231 citations

Conversion of Androstenedione to Estrone by Neural Tissues from Fetal and Neonatal Rats12

1974 • 226 citations

An autoradiographic study of the time of final division of neurons in rat hypothalamic nuclei

1972 • 213 citations

Role of fetoneonatal estrogen binding proteins in the associations of estrogen with neonatal brain cell nuclear receptors

1975 • 184 citations

Influence of rat estradiol binding plasma protein (EBP) on uterotrophic activity

1973 • 163 citations

Advancement of Puberty in the Female Rat by Estrogen

1965 • 155 citations

Independent masculinization of neuroendocrine systems by intracerebral implants of testosterone or estradiol in the neonatal female rat

1978 • 151 citations

SEX DIFFERENCES AND HORMONAL CONTROL OF TESTOSTERONE METABOLISM IN RAT PITUITARY AND BRAIN

1973 • 151 citations

PREVENTION OF CENTRAL DEFEMINIZATION BUT NOT MASCULINIZATION IN MALE RATS BY INHIBITION NEONATALLY OF OESTROGEN BIOSYNTHESIS

1977 • 145 citations

Testosterone in the Fetal Rat Testis1

1973 • 143 citations

Veränderungen des Hypophysenvorderlappens und des Ovariums nach Behandlung mit Grossen Dosen von Follikelhormon

1934 • 142 citations

HYPOTHALAMIC, PITUITARY AND TESTICULAR FUNCTION DURING SEXUAL MATURATION OF THE MALE RAT

1977 • 129 citations

Dihydrotestosterone, androstenedione, testosterone: Comparative effectiveness in masculinizing and defeminizing reproductive systems in male and female rats

1970 • 124 citations

Neurohormonal Control of Male Sexual Behavior

1974 • 117 citations

Autoradiographic Localization of 3H-Estradiol or Its Metabolites in the Central Nervous System of the Developing Rat1

1974 • 116 citations

Ultrastructural features of the developing hypothalamo-hypophysial axis in the rat

1971 • 116 citations

Conversion of Testosterone and Androstenedione to Estrogens in Vitro by the Brain of Female Rats

1974 • 115 citations

Estradiol-17β: a metabolite of testosterone recovered in cell nuclei from limbic areas of adult male rat brains

1975 • 106 citations

Androgen and Estrogen Receptors in the Developing Mouse Brain

1976 • 104 citations

The Larval Development of Imaginal Disks

1972 • 104 citations

PLASMA OESTRADIOL-17β AND ITS RELATIONSHIP TO SERUM FOLLICLE-STIMULATING HORMONE IN IMMATURE FEMALE RATS

1973 • 101 citations

RELEASING FACTOR AND HORMONAL CHANGES IN THE HYPOTHALAMIC-PITUITARY-GONADOTROPHIN AND -ADRENOCORTICOTROPHIN SYSTEMS BEFORE AND AFTER BIRTH AND PUBERTY IN MALE, FEMALE AND ANDROGENIZED FEMALE RATS

1977 • 97 citations

Ontogeny of Estradiol-Binding Sites in Rat Brain. II. Characteristics of a Neonatal Binding Macromolecule

1973 • 95 citations

The effects of an inhibitor of aromatization (1,4,6-androstatriene-3,17-dione) and an anti-estrogen (Cl-628) on in vivo formed testosterone metabolites recovered from neonatal rat brain tissues and purified cell nuclei. Implications for sexual differentiation of the rat brain

1977 • 94 citations

Sex-Dependent Changes in Pituitary 5α:-Dihydrotestosterone and 3α-Androstanediol Formation During Postnatal Development and Puberty in the Rat

1974 • 88 citations

A receptor mediating sexual differentiation?

1974 • 87 citations

Estradiol-17β: a metabolite of testosterone recovered in cell nuclei from limbic areas of neonatal rat brains

1975 • 81 citations

SEXUAL BEHAVIOUR OF NEONATALLY CASTRATED RATS INJECTED DURING INFANCY WITH OESTROGEN AND DIHYDROTESTOSTERONE

1977 • 81 citations

INFLUENCE OF AGE ON THE RELEASE OF LUTEINIZING HORMONE INDUCED BY OESTROGEN AND PROGESTERONE IN IMMATURE RATS

1972 • 80 citations

Masculinization of the female golden hamster by neonatal treatment with androgen or estrogen

1972 • 79 citations

THE INFLUENCE OF AGE ON SUPEROVULATION IN THE IMMATURE RAT AND MOUSE

1961 • 79 citations

Metabolites of Testosterone in the Brain of the Newborn Female Rat after an Injection of Tritiated Testosterone

1974 • 77 citations

Histochemistry of the Leydig Cells in the Postnatal Prepubertal Testis of the Rat

1963 • 76 citations

COMPARISON OF THE EFFECT OF NEONATAL ADMINISTRATION OF TESTOSTERONE AND DIHYDROTESTOSTERONE IN THE FEMALE RAT

1972 • 76 citations

Role of Estrogen in the Cerebral Control of Puberty in Female Rats

1968 • 75 citations

Developmental Changes in Pituitary Responsiveness to Luteinizing Hormone-Releasing Hormone (LHRH) in the Female Rat: Ovarian-Adrenal Influence During the Infantile Period1

1977 • 67 citations

The effect of antiestrogens on the nuclear binding of the estrogen receptor

1974 • 65 citations

The Biology of Imaginal Disks

1973 • 64 citations

Monoamine fluorescence in the median eminence of foetal, neonatal and adult rats

1970 • 62 citations

Neuroendocrinology: Animal models and problems of human sexuality

1975 • 60 citations

Male Rats With Inherited Insensitivity to Androgen Show Reduced Sexual Behavior

1977 • 59 citations

EFFECTS OF THE AROMATIZATION INHIBITOR ANDROST-4-ENE-3,6,17-TRIONE ON SEXUAL DIFFERENTIATION INDUCED BY TESTOSTERONE IN THE NEONATALLY CASTRATED RAT

1978 • 59 citations

Neuroendocrinology: Animal Models and Problems of Human Sexuality

1975 • 58 citations

PLASMA PROGESTERONE AND ITS RELATIONSHIP TO SERUM GONADOTROPHINS IN IMMATURE FEMALE RATS

1975 • 56 citations

Conversion of testosterone into 5α-reduced metabolites in the anterior pituitary and in the brain of maturing rats

1975 • 56 citations

PITUITARY AND PLASMA LEVELS OF GONADOTROPHINS IN FOETAL AND NEWBORN MALE AND FEMALE RATS

1976 • 56 citations

Inhibition of lordosis in female rats by subcutaneous implants of testosterone, androstenedione or dihydrotestosterone in infancy

1974 • 54 citations

Further Studies on the Maturation of the Estrogen Negative Feedback on Gonadotropin Release in the Female Rat

1975 • 51 citations

Development of bisexuality in the male rat treated neonatally with androstenedione.

1969 • 50 citations

Role of oestrogen receptor in androgen-induced sexual differentiation of the brain

1976 • 49 citations

Properties and subcellular inter-relationships of presumptive estrogen receptor macromolecules in the brains of neonatal and prepubertal female rats

1976 • 49 citations

Receptive behavior in developing female rats

1975 • 44 citations

Effects of Testosterone Propionate or Dihydrotestosterone Propionate on Plasma FSH and LH Levels in Neonatal Rats and on Sexual Differentiation of the Brain1

1975 • 42 citations

Interaction of Exogenous Steroids in the Developing Rat Brain1

1974 • 38 citations

INHIBITION, BY THE ANTI-OESTROGEN MER-25, OF DEFEMINIZATION INDUCED BY THE SYNTHETIC OESTROGEN RU 2858

1975 • 36 citations

Short-Term Steroid Treatment on Plasma LH and FSH in Castrated Rats from Birth to Puberty

1973 • 35 citations

Hormonal determinants in the development of masculine and feminine behavior in the female hamster

1974 • 34 citations

The synthesis of testosterone and estradiol-17β by the gonads of neonatal rats in vitro

1975 • 31 citations

Effects of Gonadal Steroids on the Secretion of LH and FSH in Neonatal Rats1

1971 • 29 citations

Nuclear binding of the oestrogen receptor of neonatal rat brain after injection of oestrogens and androgens; Localization and sex differences

1977 • 28 citations

Hormonal Control of Sexual Differentiation of the Hypothalamus in the Neonatal Female Rat

1974 • 26 citations

Receptivity in female hamsters following neonatal testosterone, testosterone propionate, and MER-25

1974 • 25 citations

DEVELOPMENT OF THE MECHANISMS INVOLVED IN THE FACILITATORY AND INHIBITORY EFFECTS OF OVARIAN STEROIDS ON THE RELEASE OF FOLLICLE-STIMULATING HORMONE IN THE IMMATURE RAT

1973 • 24 citations

Effect of Age of Rat and Dose of a Single Injection of Estradiol Benzoate (EB) on Ovulation and the Facilitation of Ovulation by Progesterone (P)

1971 • 24 citations

Effects of dihydrotestosterone and gonadotropins on the development of female behavior☆

1976 • 20 citations

FAILURE OF OVULATION AFTER ADMINISTRATION OF STEROID HORMONES AND HORMONE ANTAGONISTS TO FEMALE RATS DURING THE NEONATAL PERIOD

1974 • 19 citations

Hypothalamic Control of the Pituitary-Testicular Relation in Fetal Rats: Measurement of Collective Volume of Leydig Cells

1975 • 19 citations

Immunological demonstration of α-fetoprotein in uterine cytosol from immature rats

1974 • 18 citations

Alteration by Neonatal Hypothyroidism of the Critical Period for the Induction of Persistent Estrus in the Rat

1969 • 17 citations

Failure of Intrahypothalamic Implants of Antiestrogen, MER-25, to Inhibit Androgen-Sterilization in Female Rats

1974 • 16 citations

Gonadotropic Hormone Release from Fetal and Adult Rat Pituitary Glands after <i>in vitro </i>Exposure to Synthetic LH-FSH-RH

1974 • 16 citations

Masculine-like Hypothalamic-Pituitary Axis in the Androgen-Insensitive Genetically Male Rat Pseudohermaphrodite

1975 • 14 citations

Postnatal thyroxine modifies effects of early androgen on lordosis

1976 • 13 citations

OESTROGEN AND THE CONTROL OF GONADOTROPHIN SECRETION IN THE IMMATURE RAT

1974 • 11 citations

Autoradiographic localization of radioactivity in female rat neocortex after injection of tritiated estradiol

1971 • 7 citations

COMPENSATORY OVARIAN HYPERTROPHY CAN BE OBTAINED IN NEONATAL RATS

1973 • 6 citations

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