Gamete Interaction in the Sea Urchin A Model for Understanding the Molecular Details of Animal Fertilization

Mammalian sperm-egg interaction: Identification of a glycoprotein in mouse egg zonae pellucidae possessing receptor activity for sperm

1980 • 704 citations

Structure and function of the zona pellucida: Identification and characterization of the proteins of the mouse oocyte's zona pellucida

1980 • 618 citations

Calcium dependence of the acrosome reaction and activation of guinea pig spermatozoa

1974 • 587 citations

Activation of mammalian oocytes by intracellular injection of calcium

1978 • 582 citations

A free calcium wave traverses the activating egg of the medaka, Oryzias latipes.

1978 • 546 citations

Fast block to polyspermy in sea urchin eggs is electrically mediated

1976 • 456 citations

Isolation of bindin: the protein responsible for adhesion of sperm to sea urchin eggs.

1977 • 430 citations

THE POLYMERIZATION OF ACTIN: ITS ROLE IN THE GENERATION OF THE ACROSOMAL PROCESS OF CERTAIN ECHINODERM SPERM

1973 • 326 citations

Release of ovoperoxidase from sea urchin eggs hardens the fertilization membrane with tyrosine crosslinks

1977 • 313 citations

Developmental Biology of the Sea Urchin Embryo

1973 • 285 citations

Purification of the fusion protein of Sendai virus: analysis of the NH2-terminal sequence generated during precursor activation.

1978 • 283 citations

Chapter 7 Mechanisms of Activation of Sperm and Egg During Fertilization of Sea Urchin Gametes

1978 • 282 citations

Chemical characterization of the component of the jelly coat from sea urchin eggs responsible for induction of the acrosome reaction

1979 • 275 citations

Mouse Teratocarcinoma and Embryonic Antigens

1977 • 270 citations

Induction of Zona Reaction in Golden Hamster Eggs by Cortical Granule Material

1971 • 266 citations

Serological Demonstration of H–Y (Male) Antigen on Mouse Sperm

1971 • 264 citations

Polymerization of actin. IV. Role of Ca++ and H+ in the assembly of actin and in membrane fusion in the acrosomal reaction of echinoderm sperm

1978 • 255 citations

Isolation, physicochemical properties, and macromolecular composition of zona pellucida from porcine oocytes

1980 • 247 citations

The acrosome reaction of Strongylocentrotus purpuratus sperm

1978 • 227 citations

Chemistry and Physiology of Fertilization

1965 • 217 citations

THE ZONA REACTION OF HAMSTER AND MOUSE EGGS: PRODUCTION IN VITRO BY A TRYPSIN-LIKE PROTEASE FROM CORTICAL GRANULES

1973 • 212 citations

STUDIES ON THE ACROSOME. I. REACTION TO EGG-WATER AND OTHER STIMULI

1952 • 210 citations

Bioelectric Responses of the Echinoderm Egg to Fertilization

1971 • 199 citations

Monographs on Endocrinology

2009 • 198 citations

The role of calcium in the acrosome reaction: An analysis using ionophore A23187

1976 • 197 citations

Problems of Fertilization.

1919 • 192 citations

Hardening of the sea urchin fertilization envelope by peroxidase-catalyzed phenolic coupling of tyrosines

1978 • 181 citations

STUDIES ON THE ACROSOME. III. EFFECT OF CALCIUM DEFICIENCY

1954 • 168 citations

Penetration of Zona-Free Eggs by Spermatozoa of Different Species

1972 • 168 citations

Protease released from sea urchin eggs at fertilization alters the vitelline layer and aids in preventing polyspermy

1973 • 163 citations

Development in mammals

1977 • 158 citations

A partial sequence of ionic changes associated with the acrosome reaction of Strongylocentrotus purpuratus

1981 • 158 citations

The Acrosome Reaction

1956 • 154 citations

Surface domains of the guinea pig sperm defined with monoclonal antibodies

1981 • 150 citations

Egg surface glycoprotein receptor for sea urchin sperm bindin.

1978 • 146 citations

The role of calcium ions in the acrosome reaction of sea urchin sperm

1977 • 145 citations

Isolation and biological activity of the proteases released by sea urchin eggs following fertilization

1975 • 145 citations

Species specific agglutination of eggs by bindin isolated from sea urchin sperm

1977 • 139 citations

Acrosome Reaction and Lysins

1967 • 135 citations

Methods for quantitating sea urchin sperm-egg binding

1973 • 133 citations

Identification of a sperm receptor on the surface of the eggs of the sea urchin Arbacia punctulata.

1977 • 130 citations

Studies on the acrosome

1964 • 124 citations

Fertilization of guinea pig eggs in vitro

1972 • 124 citations

The polymerization of actin. III. Aggregates of nonfilamentous actin and its associated proteins: a storage form of actin.

1976 • 117 citations

Protease Activity establishes the Block against Polyspermy in Sea Urchin Eggs

1972 • 116 citations

Further evidence in support of a role for hamster sperm hydrolytic enzymes in the acrosome reaction

1979 • 116 citations

The regulation of spermatozoa by calcium cyclic nucleotides.

1980 • 116 citations

A study of factors involved in induction of the acrosomal reaction in sperm of the sea urchin, Arbacia punctulata

1976 • 116 citations

The Vitelline Membrane and Cortical Particles in Sea Urchin Eggs and Their Function in Maturation and Fertilization

1966 • 114 citations

The polymerization of actin: II. how nonfilamentous actin becomes nonrandomly distributed in sperm: evidence for the association of this actin with membranes

1976 • 110 citations

The sea urchin embryo : biochemistry and morphogenesis

1975 • 108 citations

The Functional Anatomy of the Echinoderm Spermatozoon and its Interaction with the Egg at Fertilization

1975 • 108 citations

Membrane Fusion in Relation to Sperm-Egg Association**Part of the work reported here was supported by National Institutes of Health research grants GM-04948 and HD-00007.

1967 • 106 citations

Chemotaxis during fertilization in the hydroid Campanularia

1966 • 101 citations

Species-specificity of acrosome reaction and primary gamete binding in echinoids

1975 • 101 citations

The vitelline layer of the sea urchin egg and its modification during fertilization. A freeze-fracture study using quick-freezing and deep-etching.

1980 • 100 citations

Sperm chemotaxis in the hydromedusae. I. Species-specificity and sperm behavior

1979 • 100 citations

Intracellular calcium release and the mechanisms of parthenogenetic activation of the sea urchin egg

1978 • 99 citations

Sperm-Egg Interaction: Evidence for Boar Sperm Plasma Membrane Receptors for Porcine Zona Pellucida

1980 • 99 citations

Properties of Fertilizin and Related Substances of Eggs and Sperm of Marine Animals

1949 • 97 citations

Chemotaxis of the spermatozoa of Ciona intestinalis

1975 • 96 citations

NS-4 (nervous system antigen-4), a cell surface antigen of developing and adult mouse brain and sperm

1975 • 94 citations

Chapter 2 Immunoperoxidase Localization of Bindin During the Adhesion of Sperm to Sea Urchin Eggs

1979 • 89 citations

Sperm-egg association in animals.

1978 • 86 citations

Species-specific sperm adhesion in sea urchins. A quantitative investigation of bindin- mediated egg agglutination

1979 • 86 citations

Chemotactic Turning Behaviour of Tubularia Spermatozoa

1970 • 84 citations

Isolation and characterization of the vitelline layer of sea urchin eggs.

1977 • 84 citations

H-Y Antigen and the Genetics of Sex Determination

1977 • 83 citations

Polymerization of actin. V. A new organelle, the actomere, that initates the assembly of actin filaments in Thyone sperm

1978 • 80 citations

H-Y Antigen: Behavior and Function

1977 • 79 citations

Ovoperoxidase activity in ionophore treated mouse eggs. II. Evidence for the enzyme's role in hardening the zona pellucida

1980 • 78 citations

Isolation of a spermatozoid-releasing and -attracting substance from female gametophytes of Laminaria digitata

1979 • 77 citations

Actin filament-membrane attachment: are membrane particles involved?

1976 • 75 citations

Gamete Surface Components and Their Role in Fertilization**Contribution No. 063 from the Institute of Molecular Evolution. During preparation of this manuscript, support was received from the National Aeronautics and Space Administration (NsG 689), the National Science Foundation (GB 3899), and the National Institutes of Health (5T1 HD 26-04).

1967 • 74 citations

Chapter 4 Sperm-Egg Association in Mammals

1978 • 70 citations

Ionophore A23187 induces acrosome reactions in sea urchin and guinea pig spermatozoa

1976 • 64 citations

Surface activity at the egg plasma membrane during sperm incorporation and its cytochalasin B sensitivity

1980 • 64 citations

Tryptic disruption of sperm-binding site of sea urchin egg surface

1972 • 64 citations

An antiserum specific for cholinergic synaptic vesicles from electric organ.

1980 • 63 citations

A reevaluation of the fertilizin hypothesis of sperm agglutination and the description of a novel form of sperm adhesion

1976 • 63 citations

Phospholipase activity of sea urchin sperm: Its possible involvement in membrane fusion

1976 • 59 citations

The jelly and vitelline coats of the sea urchin egg: new ultrastructural features

1978 • 57 citations

H-Y Antigen: Genetics and Serology

1977 • 55 citations

Chapter 6 Transformations of Sperm Nuclei Upon Insemination

1978 • 53 citations

Physiological studies on the sperm surface component responsible for sperm-egg bonding in sea urchin fertilization

1975 • 52 citations

Physiological studies on the sperm surface component responsible for sperm-egg bonding in sea urchin fertilization

1973 • 52 citations

Regional differentiation of the sperm surface as studied with 125I-diiodofluorescein isothiocyanate, an impermeant reagent that allows isolation of the labeled components.

1979 • 51 citations

Polymerization of Actin

1966 • 50 citations

THE FERTILIZING CAPACITY OF SEA URCHIN SPERM RAPIDLY DECREASES AFTER INDUCTION OF THE ACROSOME REACTION*

1979 • 49 citations

Jelly coat substances of sea urchin eggs I. Sperm isoagglutination and sialopolysaccharide in the jelly

1970 • 49 citations

Brain and sperm cell surface antigen (NS-4) on preimplantation mouse embryos

1976 • 48 citations

Involvement of an acrosin-like enzyme in the acrosome reaction of sea urchin sperm

1979 • 47 citations

BIOCHEMICAL DETECTION AND ACTIVATION OF AN INACTIVE FORM OF A TRYPSIN-LIKE ENZYME IN RABBIT TESTES

1972 • 46 citations

Primary gamete binding

1976 • 45 citations

Purification of the sperm-binding factor from the egg of the sea urchin, Hemicentrotus pulcherrimus

1977 • 45 citations

Separation of the Sperm Agglutinin and the Acrosome Reaction-Inducing Substance in Egg Jelly of Starfish

1978 • 44 citations

Isolation of a high molecular weight glycoconjugate derived from the surface of S purpuratus eggs that is implicated in sperm adhesion

1981 • 43 citations

Isolation of sperm bindin from the oyster (Crassostrea gigas)

1978 • 41 citations

ON THE SPERM‐EGG BONDING AS THE INITIAL STEP OF FERTILIZATION IN THE SEA URCHIN*

1967 • 41 citations

Membrane events in the acrosomal reaction of Limulus sperm. Membrane fusion, filament-membrane particle attachment, and the source and formation of new membrane surface.

1979 • 40 citations

Ultrastructural Demonstration of Trypsin-Like Protease in Acrosomes of Sea Urchin Sperm

1980 • 40 citations

Antibody to a sperm surface glycoprotein inhibits the egg jelly-induced acrosome reaction of sea urchin sperm

1980 • 39 citations

The Sea Urchin Embryo

1975 • 38 citations

Chapter 5 Sperm and Egg Receptors Involved in Fertilization

1978 • 38 citations

NS-6 (nervous system antigen-6): A new cell surface antigen of brain, kidney, and spermatozoa

1978 • 37 citations

Guanylate cyclase of sea urchin sperm: Subcellular localization

1976 • 36 citations

Studies on the specificity of sperm binding in echinoderm fertilization

1980 • 32 citations

Purification of an acrosin-like enzyme from sea urchin sperm.

1980 • 32 citations

Interaction of immunoglobulin fragments with the mammalian sperm acrosome

1978 • 31 citations

THE EFFECT OF SOLUBLE EGG JELLY ON THE FERTILIZABILITY OF ACID-DEJELLIED SEA URCHIN EGGS*

1979 • 31 citations

Radial cortical fibers and pronuclear migration in fertilized and artificially activated eggs of Lytechinus pictus

1980 • 30 citations

THE DISTRIBUTION OF SUBSTANCES IN THE SPERMATOZOÖN (ARBACIAANDNEREIS)

1927 • 30 citations

Radioiodination and characterization of the plasma membrane of sea urchin sperm

1980 • 28 citations

INTERACTIONS BETWEEN ARBACIA SPERM AND S³⁵—LABELLED FERTILIZIN

1961 • 24 citations

Sperm chemotaxis in the hydromedusae. II. Some chemical properties of the sperm attractants

1979 • 24 citations

The Interactions of Sea Urchin Gametes During Fertilization

1979 • 23 citations

Characterization and comparison of “bindin” isolated from sperm of two species of sea urchins

1977 • 23 citations

Properties and Partial Purification of the Sperm Attractant ofTubularia

1974 • 22 citations

SPERM AGGLUTINATION AND FERTILIZATION

1915 • 21 citations

Sperm-specific surface antigenicity common to seven animal phyla

1980 • 19 citations

The Polymerization of Actin

1981 • 16 citations

Membrane Damage to Immunologically Immobilized Rabbit Spermatozoa Visualized by Immunofluorescence and Scanning Electron Microscopy1

1975 • 11 citations

A study on the possible significance of carbohydrate moiety in the sperm-binding protein from sea urchin egg

1969 • 11 citations

The Adhesion of Sperm to Sea Urchin Eggs

1980 • 8 citations