Interaction of liver microsomal cytochrome P-450 and NADPH-cytochrome P-450 reductase in the presence and absence of lipid.

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

1982 • 1,021 citations

The O-Dealkylation of 7-Ethoxycoumarin by Liver Microsomes. A Direct Fluorometric Test

1972 • 634 citations

Role of Hemoprotein P-450 in Fatty Acid ω-Hydroxylation in a Soluble Enzyme System from Liver Microsomes

1968 • 625 citations

Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450

1976 • 536 citations

Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest.

1977 • 367 citations

[39] Direct fluorometric methods for measuring mexed-function oxidase activity

1978 • 362 citations

Purified liver microsomal NADPH-cytochrome P-450 reductase. Spectral characterization of oxidation-reduction states.

1978 • 346 citations

Membrane Proteins in Transport and Phosphorylation

1975 • 321 citations

Lipid composition of mitochondria from bovine heart, liver, and kidney

1967 • 269 citations

Separation and purification of multiple forms of microsomal cytochrome P-450. Partial characterization of three apparently homogeneous cytochromes P-450 prepared from livers of phenobarbital- and 3-methylcholanthrene-treated rats

1978 • 255 citations

The Structural Basis of Membrane Function

1976 • 253 citations

Temperature dependence of cytochrome P-450 reduction. A model for NADPH-cytochrome P-450 reductase:cytochrome P-450 interaction.

1976 • 241 citations

Purification of cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydratase from a single preparation of rat liver microsomes

1980 • 228 citations

Interactions of cytochrome P-450, NADPH-cytochrome P-450 reductase, phospholipid, and substrate in the reconstituted liver microsomal enzyme system.

1980 • 224 citations

[70] Removal and binding of polar lipids in mitochondria and other membrane systems

1967 • 210 citations

Two nonspecific phospholipid exchange proteins from beef liver. 1. Purification and characterization

1980 • 210 citations

Studies on the Mechanism of Microsomal Triphosphopyridine Nucleotide-Cytochrome c Reductase

1965 • 201 citations

[69] Isolation, characterization, and determination of polar lipids of mitochondria

1967 • 181 citations

Oxidation-reduction properties of rat liver cytochromes P-450 and NADPH-cytochrome P-450 reductase related to catalysis in reconstituted systems

1983 • 177 citations

Interaction between NADPH-cytochrome p-450 reductase and cytochrome p-450 in the membrane of phosphatidylcholine vesicles

1979 • 159 citations

Synthesis of glycerophospholipids

1980 • 150 citations

The role of soluble lipid in mitochondrial enzyme systems

1961 • 146 citations

Structure and Function of Membrane Proteins

1983 • 145 citations

Studies on the association of cytochrome P-450 and NADPH-cytochrome c reductase during catalysis in a reconstituted hydroxylating system.

1979 • 135 citations

[53] Preparation of phospholipids and their analogs by phospholipase D

1981 • 134 citations

Purified liver microsomal cytochrome P-450. Electron-accepting properties and oxidation-reduction potential.

1975 • 120 citations

Studies on the rate-limiting enzyme component in the microsomal monooxygenase system. Incorporation of purified NADPH-cytochrome c reductase and cytochrome P-450 into rat liver microsomes.

1978 • 117 citations

Reactions Catalyzed by the Cytochrome P-450 System

1980 • 95 citations

Alteration of synaptic membrane cholesterol/phospholipid ratio using a lipid transfer protein. Effect on gamma-aminobutyric acid uptake.

1983 • 94 citations

Preparation and properties of highly purified cytochrome p-450 and NADPH-cytochrome P-450 reductase from pulmonary microsomes of untreated rabbits.

1977 • 93 citations

The synthesis of phospholipids by direct amination

1978 • 81 citations

Steps in the formation and decomposition of some enzyme-substrate complexes

1955 • 79 citations

Rotation of cytochrome P-450. II. Specific interactions of cytochrome P-450 with NADPH-cytochrome P-450 reductase in phospholipid vesicles.

1982 • 76 citations

Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates

1974 • 74 citations

Relationship between state of aggregation and catalytic activity for cytochrome P-450LM2 and NADPH-cytochrome P-450 reductase.

1982 • 71 citations

An improved method for the preparation of 1,2-isopropylidene-SN-glycerol

1981 • 67 citations

Membrane charge as effector of cytochrome P-450LM2 catalyzed reactions in reconstituted liposomes

1981 • 56 citations

Hydrodynamic characterization of highly purified and functionally active liver microsomal cytochrome P-450

1979 • 53 citations

Studies on the stimulation of cytochrome P-450-dependent monooxygenase activity by dilauroylphosphatidylcholine

1981 • 48 citations

Cross-linking studies of cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase

1980 • 37 citations

Analysis of interactions among purified components of the liver microsomal cytochrome P-450-containing monooxygenase system by second derivative spectroscopy

1980 • 33 citations

Organic Solvent Extraction of Liver Microsomal Lipid: II. Effect on the Metabolism of Substrates and Binding Spectra of Cytochrome P-450

1974 • 30 citations

The insertion of purified D-beta-hydroxybutyrate apodehydrogenase into membranes.

1979 • 29 citations

Interaction of epoxide hydrolase with itself and other microsomal proteins

1982 • 27 citations

Phospholipid transfer between vesicles

1982 • 10 citations

O-Demethylation of Scoparone and Studies on the Scoparone-induced Spectral Change of Cytochrome P-450 in Rat Liver Microsomes

1981 • 8 citations

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