Role of Low Density Lipoprotein Oxidation in Foam Cell Formation

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

1981 • 1,325 citations

Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation.

1984 • 994 citations

Malondialdehyde-Altered Protein Occurs in Atheroma of Watanabe Heritable Hyperlipidemic Rabbits

1988 • 757 citations

Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid.

1983 • 623 citations

Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages.

1980 • 475 citations

Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism.

1987 • 473 citations

Enhanced macrophage degradation of biologically modified low density lipoprotein.

1983 • 469 citations

The role of the monocyte in atherogenesis: II. Migration of foam cells from atherosclerotic lesions.

1981 • 468 citations

George Lyman Duff Memorial Lecture. Atherosclerosis: a problem of the biology of arterial wall cells and their interactions with blood components.

1981 • 456 citations

Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor.

1986 • 417 citations

Enhanced macrophage uptake of low density lipoprotein after self-aggregation.

1988 • 371 citations

Fatty streak initiation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits.

1987 • 337 citations

Lipoproteins and atherosclerosis. A look back and a look ahead.

1983 • 315 citations

Superoxide initiates oxidation of low density lipoprotein by human monocytes.

1987 • 273 citations

Cholesterol esterification in macrophages. Stimulation by lipoproteins containing apo B isolated from human aortas.

1984 • 107 citations

Characterization of two lipoproteins containing apolipoproteins B and E from lesion-free human aortic intima.

1988 • 100 citations

A low density lipoprotein-sized particle isolated from human atherosclerotic lesions is internalized by macrophages via a non-scavenger-receptor mechanism.

1990 • 87 citations

Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity.

1987 • 85 citations

Probucol prevents lipid storage in macrophages

1986 • 69 citations

Platelet-Mediated Cholesterol Accumulation in Cultured Aortic Smooth Muscle Cells

1985 • 68 citations

Accumulation of cholesteryl ester and lipid droplets in macrophages after uptake of cholesterol-rich necrotic products.

1987 • 12 citations