In vitro replication of mitochondrial DNA. Elongation of the endogenous primer sequence in D loop mitochondrial DNA by human DNA polymerase beta.

DNA gyrase: an enzyme that introduces superhelical turns into DNA.

1976 • 1,175 citations

The interaction of closed circular DNA with intercalative dyes

1968 • 627 citations

Studies of the binding of Escherichia coli RNA polymerase to DNA

1972 • 459 citations

The degree of unwinding of the DNA helix by ethidium

1974 • 440 citations

An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication

1972 • 332 citations

A Novel Closed-Circular Mitochondrial DNA with Properties of a Replicating Intermediate

1971 • 271 citations

A mechanism of duplex DNA replication revealed by enzymatic studies of phage phi X174: catalytic strand separation in advance of replication.

1977 • 223 citations

Multienzyme Systems of DNA Replication

1974 • 222 citations

Purification and physical characterization of nucleic acid helix-unwinding proteins from calf thymus.

1976 • 211 citations

Purification and Properties of Nuclear and Cytoplasmic Deoxyribonucleic Acid Polymerases from Human KB Cells

1972 • 203 citations

Nomenclature of Eukaryotic DNA Polymerases

1975 • 168 citations

Mechanism of mitochondrial DNA replication in mouse L-cells: Asynchronous replication of strands, segregation of circular daughter molecules, aspects of topology and turnover of an initiation sequence

1974 • 162 citations

DNA polymerase-alpha. Purification and structural characterization of the near homogeneous enzyme from human KB cells.

1977 • 161 citations

Replication of Mitochondrial DNA in Mouse L Cells and Their Thymidine Kinase ^- Derivatives: Displacement Replication on a Covalently-Closed Circular Template

1972 • 134 citations

DNA Synthesis in Isolated HeLa Nuclei

1973 • 130 citations

Replication of polyoma DNA in isolated nuclei

1972 • 124 citations

DNA synthesis in human lymphocytes: Intermediates in DNA synthesis, in vitro and in vivo

1975 • 122 citations

In vivo effects of intercalating drugs on the superhelix density of mitochondrial DNA isolated from human and mouse cells in culture

1971 • 122 citations

The sense of naturally occurring superhelices and the unwinding angle of intercalated ethidium

1975 • 120 citations

Synthesis of herpes simplex virus, vaccinia virus, and adenovirus DNA in isolated HeLa cell nuclei. I. Effect of viral-specific antisera and phosphonoacetic acid

1975 • 117 citations

Characterization of purified DNA-relaxing enzyme from human tissue culture cells.

1975 • 116 citations

Restriction Endonuclease Cleavage Maps of Animal Mitochondrial DNAs

1974 • 112 citations

Nuclear Deoxyribonucleic Acid Polymerase

1974 • 111 citations

Homology and structural relationships between the dimeric and monomeric circular forms of mitochondrial DNA from human leukemic leukocytes

1970 • 106 citations

Bacteriophage T7 Deoxyribonucleic Acid Replication in Vitro

1974 • 89 citations

A Single-Strand-Specific DNA-Binding Protein from Mouse Cells that Stimulates DNA Polymerase.. Its Modification by Phosphorylation

1977 • 84 citations

Isolation and Partial Characterisation of the Relaxation Protein from Nuclei of Cultured Mouse and Human Cells

1975 • 77 citations

Enzymatic replication of viral and complementary strands of duplex DNA of phage phiX174 proceeds by seprate mechanisms.

1976 • 68 citations

Mechanism of mitochondrial DNA replication in mouse L-cells: Topology of circular daughter molecules and dynamics of catenated oligomer formation

1976 • 55 citations

DNA replication in SV40-infected cells

1973 • 50 citations

Cleavage of Replicating Forms of Mitochondrial DNA by Eco RI Endonuclease

1974 • 43 citations