Anti-phospholamban and protein kinase A alter the Ca2+ sensitivity and maximum velocity of Ca2+ uptake by the cardiac sarcoplasmic reticulum

Myoplasmic free calcium concentration reached during the twitch of an intact isolated cardiac cell and during calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned cardiac cell from the adult rat or rabbit ventricle.

1981 • 572 citations

Nature and site of phospholamban regulation of the Ca2+ pump of sarcoplasmic reticulum

1989 • 449 citations

Phosphorylation of the Sarcoplasmic Reticulum and Sarcolemma

1982 • 441 citations

Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains.

1986 • 435 citations

cDNA Cloning, functional expression, and mRNA Tissue Distribution of a Third Organellar Ca2+ Pump

1989 • 412 citations

Biochemistry of Smooth Muscle Contraction

1996 • 306 citations

Molecular mechanism of regulation of Ca2+ pump ATPase by phospholamban in cardiac sarcoplasmic reticulum. Effects of synthetic phospholamban peptides on Ca2+ pump ATPase.

1992 • 184 citations

Structural organization of the pentameric transmembrane alpha-helices of phospholamban, a cardiac ion channel.

1994 • 183 citations

Regional Changes in Calcium Underlying Contraction of Single Smooth Muscle Cells

1987 • 179 citations

Isolation and characterization of canine cardiac sarcoplasmic reticulum with improved Ca2+ transport properties.

1983 • 164 citations

Comparative studies of cardiac and skeletal sarcoplasmic reticulum ATPases. Effect of a phospholamban antibody on enzyme activation by Ca2+

1993 • 161 citations

Functional reconstitution of the cardiac sarcoplasmic reticulum Ca2(+)-ATPase with phospholamban in phospholipid vesicles.

1990 • 160 citations

Stimulation of bovine cardiac sarcoplasmic reticulum Ca2+ pump and blocking of phospholamban phosphorylation and dephosphorylation by a phospholamban monoclonal antibody.

1986 • 144 citations

Phospholamban forms Ca2+-selective channels in lipid bilayers.

1988 • 140 citations

Physiology and Pathophysiology of the Heart

1990 • 137 citations

Structural Model of the Phospholamban Ion Channel Complex in Phospholipid Membranes

1995 • 129 citations

The max of the Ca2+-ATPase of Cardiac Sarcoplasmic Reticulum (SERCA2a) Is Not Altered by Ca2+/Calmodulin-dependent Phosphorylation or by Interaction with Phospholamban

1996 • 124 citations

Sarcoplasmic reticulum Ca2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes.

1993 • 121 citations

Purified, Reconstituted Cardiac Ca2+-ATPase Is Regulated by Phospholamban but Not by Direct Phosphorylation with Ca2+/Calmodulin-dependent Protein Kinase

1996 • 106 citations

Functional Reconstitution of Recombinant Phospholamban with Rabbit Skeletal Ca2+-ATPase

1995 • 95 citations

Dependence of cardiac sarcoplasmic reticulum calcium pump activity on the phosphorylation status of phospholamban.

1991 • 90 citations

The physical mechanism of calcium pump regulation in the heart

1994 • 87 citations

Phospholamban regulation of cardiac sarcoplasmic reticulum (Ca(2+)-Mg2+)-ATPase. Mechanism of regulation and site of monoclonal antibody interaction

1991 • 86 citations

The sarcoplasmic reticulum calcium pump is functionally altered in dystrophic muscle

1996 • 79 citations

Phospholamban, activator of the cardiac sarcoplasmic reticulum calcium pump. Physicochemical properties and diagonal purification

1980 • 77 citations

Regulation of the Ca²⁺ pump atpase by cAMP‐dependent phosphorylation of phospholamban

1989 • 68 citations

Control of the calcium pump of cardiac sarcoplasmic reticulum. A specific role for the pentameric structure of phospholamban?

1993 • 53 citations

Translation of Ser16 and Thr17 phosphorylation of phospholamban into Ca2+-pump stimulation

1996 • 47 citations

An investigation of the mechanism of inhibition of the Ca2+-ATPase by phospholamban

1996 • 46 citations

Phospholamban is related to the autoinhibitory domain of the plasma membrane calcium-pumping ATPase

1991 • 32 citations

Continuous monitoring of Ca2+ uptake in membrane vesicles with fura-2

1988 • 28 citations

Methods for determining cardiac sarcoplasmic reticulum Ca2+ pump kinetics from fura 2 measurements

1994 • 24 citations

Examination of the role of phosphorylation and phospholamban in the regulation of the cardiac sarcoplasmic reticulum Cl? channel

1995 • 20 citations

Direct measurement of Ca2+ uptake and release by the sarcoplasmic reticulum of saponin permeabilized isolated smooth muscle cells.

1995 • 15 citations

Characterization of the molecular form of cardiac phospholamban

1994 • 11 citations

The Hydrophilic Domain of Phospholamban Inhibits the Ca2+-ATPase - The Importance of the Method of Assay

1995 • 5 citations

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