Aetiology and Pathophysiology of Malignant Hyperthermia

Calmodulin Plays a Pivotal Role in Cellular Regulation

1980 • 2,441 citations

Calmodulin

1980 • 982 citations

Adenyl Cyclase

1962 • 853 citations

THE RELATION OF ADENOSINE-3', 5'-PHOSPHATE AND PHOSPHORYLASE TO THE ACTIONS OF CATECHOLAMINES AND OTHER HORMONES

1960 • 852 citations

Calcium Induced Release of Calcium from the Sarcoplasmic Reticulum of Skinned Skeletal Muscle Fibres

1970 • 802 citations

Handbook of Experimental Pharmacology, vol 14.

1972 • 446 citations

METABOLIC ERROR OF MUSCLE METABOLISM AFTER RECOVERY FROM MALIGNANT HYPERTHERMIA

1970 • 318 citations

Studies on the mechanism of action of dantrolene sodium

1972 • 278 citations

Actions of sympathomimetic amines and their antagonists on skeletal muscle.

1969 • 272 citations

Calcium and the Heart

1971 • 214 citations

Reversible Stimulation of Muscle Phosphorylase b Kinase by Low Concentrations of Calcium Ions

1967 • 198 citations

Excitation-contraction uncoupling in skeletal muscle by dantrolene sodium

1972 • 162 citations

Troponin as the Ca++-receptive Protein in the Contractile System*

1967 • 161 citations

Abnormality in calcium release from skeletal sarcoplasmic reticulum of pigs susceptible to malignant hyperthermia.

1983 • 142 citations

The effect of methylxanthines and local anesthetics on fragmented sarcoplasmic reticulum.

1969 • 131 citations

Distribution of adenyl-cyclase activity in rabbit skeletal-muscles fractions

1965 • 129 citations

Biochemical Basis of Malignant Hyperpyrexia

1974 • 128 citations

Kinetic studies of Ca2+ release from sarcoplasmic reticulum of normal and malignant hyperthermia susceptible pig muscles

1984 • 116 citations

Activation of skeletal muscle phosphorylase.

1966 • 112 citations

PORCINE MALIGNANT HYPERTHERMIA. I: METABOLIC AND PHYSIOLOGICAL CHANGES

1976 • 111 citations

Malignant hyperthermia: an investigation of five patients

1973 • 96 citations

Halothane-induced Porcine Malignant Hyperthermia

1976 • 89 citations

Action of halothane upon mitochondrial respiration

1971 • 87 citations

Calcium-Induced Calcium Release and “Depolarization”-Induced Calcium Release: their Physiological Significance

1975 • 83 citations

Second International Symposium on Malignant Hyperthermia.

1978 • 83 citations

Malignant Hyperthermia of Swine

1972 • 82 citations

Dantrolene in Porcine Malignant Hyperthermia

1976 • 78 citations

Malignant Hyperthermia of Poland China Swine

1972 • 77 citations

Malignant hyperthermia : current concepts

1977 • 73 citations

Skeletal muscle mitochondrial phospholipase A2 and the interaction of mitochondria and sarcoplasmic reticulum in porcine malignant hyperthermia

1981 • 69 citations

Etiology and Pathophysiology of Malignant Hyperthermia

1979 • 65 citations

Mitochondrial calcium transport and calcium-activated phospholipase in porcine malignant hyperthermia

1981 • 64 citations

The trigger for PSE condition in stress‐susceptible pigs

1976 • 61 citations

Requirement of Ca Ion for the Stimulating Effect of Cyclic 3′, 5′-AMP on Muscle Phosphorylase b Kinase*

1967 • 59 citations

Procaine in Malignant Hyperpyrexia

1972 • 56 citations

Second International Symposium on Malignant Hyperthermia

1978 • 55 citations

International Symposium on Malignant Hyperthermia.

1973 • 55 citations

PORCINE MALIGNANT HYPERTHERMIA III: ADRENERGIC BLOCKADE

1976 • 53 citations

Role of Sympathetic Activity in Porcine Malignant Hyperthermia

1977 • 52 citations

Porcine Malignant Hyperthermia:

1975 • 52 citations

PORCINE MALIGNANT HYPERTHERMIA. II: HEAT PRODUCTION

1976 • 46 citations

PORCINE MALIGNANT HYPERTHERMIA. V: FATAL HYPERTHERMIA IN THE PIETRAIN PIG, ASSOCIATED WITH THE INFUSION OF α-ADRENERGIC AGONISTS

1977 • 45 citations

Porcine malignant hyperthermia: observations on the occurrence of pale, soft, exudative musculature among susceptible pigs.

1974 • 45 citations

Pigs susceptible to energy metabolism in the fulminant hyperthermia stress syndrome.

1975 • 45 citations

The adenosine triphosphate (ATP) depletion test: Comparison with the caffeine contracture test as a method of diagnosing malignant hyperthermia susceptibility

1976 • 45 citations

Toxicity of Anesthetics

1975 • 43 citations

Effect of pH and halothane on muscle and liver mitochondria

1973 • 40 citations

Malignant Hyperthermia

1982 • 39 citations

Role of cholesterol in the Ca2+ uptake and ATPase activity of fragmented sarcoplasmic reticulum

1972 • 38 citations

Serum Creatine Phosphokinase Levels in Pigs Reacting Abnormally to Halogenated Anaesthetics

1970 • 38 citations

MYOCARDIAL METABOLISM AND HEART DISEASE

1978 • 35 citations

Treatment of porcine malignant hyperthermia.

1975 • 35 citations

Phospholipase A2 activity, calmodulin, Ca2+ and meat quality in young and adult halothane-sensitive and halothane-insensitive British Landrace pigs

1986 • 34 citations

PORCINE MALIGNANT HYPERTHERMIA. VI: THE EFFECTS OF BILATERAL ADRENALECTOMY AND PRETREATMENT WITH BRETYLIUM ON THE HALOTHANE-INDUCED RESPONSE

1978 • 33 citations

A study of the action of caffeine, halothane, potassium chloride and procaine on normal human skeletal muscle

1974 • 32 citations

Prevention of Porcine Malignant Hyperthermia by Epidural Block

1975 • 32 citations

Malignant Hyperthermia in a Family

1973 • 31 citations

CALCIUM UPTAKE INTO MUSCLE OF PIGS SUSCEPTIBLE TO MALIGNANT HYPERTHERMIA: IN VITRO AND IN VIVO STUDIES WITH AND WITHOUT HALOTHANE

1975 • 30 citations

International Symposium on Malignant Hyperthermia

1973 • 29 citations

Calcium movements in skeletal muscle mitochondria of malignant hyperthermic pigs

1978 • 28 citations

Reversible Change in Physical State of Troponin Induced by Calcium Ion*

1968 • 28 citations

MALIGNANT HYPERTHERMIA DURING ANAESTHESIA

1971 • 28 citations

Catecholamine Stimulation of Myocardial Oxygen Consumption in Porcine Malignant Hyperthermia

1978 • 28 citations

Porcine Malignant Hyperthermia Induced by Halothane and Succinylcholine

1976 • 28 citations

MALIGNANT HYPERPYREXIAL DEATHS IN A FAMILY: Reports of Three Cases

1970 • 26 citations

Motor Unit Counting and the Caffeine Contracture Test in Malignant Hyperthermia

1977 • 25 citations

Skeletal-muscle mitochondria and phospholipase A2 in malignant hyperthermia

1984 • 25 citations

Thermal Inactivation of the Calcium Regulatory Mechanism of Human Skeletal Muscle Actomyosin

1975 • 24 citations

Skeletal Muscle Mitochondria in Porcine Malignant Hyperthermia

1979 • 24 citations

MALIGNANT HYPERTHERMIA: A HUMAN AND PORCINE STRESS SYNDROME?

1975 • 23 citations

Calcium uptake by isolated sarcoplasmic reticulum: examination of halothane inhibition, pH dependence, and Ca2+ dependence of normal and malignant hyperthermic human muscle.

1981 • 22 citations

High skeletal muscle adenylate cyclase in malignant hyperthermia.

1981 • 22 citations

Insulin Secretion in Malignant Hyperpyrexia

1974 • 21 citations

Temperature perturbation studies of sarcoplasmic reticulum from malignant hyperthermia pig muscle.

1979 • 20 citations

Dantrolene does not block calcium pulse‐induced calcium release from a putative calcium channel in sarcoplasmic reticulum from malignant hyperthermia and normal pig muscle

1984 • 20 citations

Increased Myophosphorylase A in Malignant Hyperthermia

1980 • 20 citations

Drug Treatment of Malignant Hyperpyrexia

1977 • 19 citations

Calcium content and contracture in isolated muscle of malignant hyperthermia in pigs.

1981 • 19 citations

MALIGNANT HYPERTHERMIA: A STUDY OF AN AFFECTED FAMILY

1972 • 19 citations

Prolonged electromechanical coupling time intervals in skeletal muscle of pigs susceptible to malignant hyperthermia

1983 • 18 citations

In Vivo Induced Malignant Hyperthermia in Pigs. I. Physiological and Biochemical Changes and the Influence of Dantrolene Sodium

1984 • 18 citations

In VivoInduced Malignant Hyperthermia in Pigs. III. Localization of Calcium in Skeletal Muscle Mitochondria by Means of Electronmicroscopy and Microprobe Analysis

1984 • 17 citations

Hereditary malignant hyperpyrexia associated with muscle adenylate kinase deficiency

1974 • 17 citations

TOTAL CALCIUM CONTENT OF SKELETAL MUSCLE ISOLATED FROM HUMANS AND PIGS SUSCEPTIBLE TO MALIGNANT HYPERTHERMIA

1975 • 15 citations

Failure of the Tourniquet-Twitch Test as a Diagnostic or Screening Test for Malignant Hyperthermia

1986 • 15 citations

Preanesthetic Evaluation and Management of Malignant Hyperthermia in the Pig Experimental Model

1976 • 14 citations

In Vivo Induced Malignant Hyperthermia in Pigs II. Metabolism of Skeletal Muscle Mitochondria

1984 • 14 citations

CYCLIC AMP IN NORMAL AND MALIGNANT HYPERPYREXIA SUSCEPTIBLE INDIVIDUALS FOLLOWING EXERCISE *

1984 • 14 citations

Correction of Adverse Response to Suxamethonium of Susceptible Pigs

1973 • 14 citations

Gluconeogenesis from Lactate in Liver of Stress-Susceptible and Stress-Resistant Pigs

1976 • 13 citations

Failure of the platelet-halothane nucleotide depletion test as a diagnostic or screening test for malignant hyperthermia.

1986 • 12 citations

Effect of Diltiazem, a New Anti-Ca<sup>++</sup> Agent, on Left Ventricular Function in Patients with and without Angina Pectoris

1976 • 11 citations

CALCIUM AND MAGNESIUM CONTENTS OF MALIGNANT HYPERPYREXIA-SUSCEPTIBLE HUMAN MUSCLE

1977 • 10 citations

Malignant hyperthermia--an investigation of three patients.

1971 • 8 citations

EXPERIMENTAL PORCINE MALIGNANT HYPERTHERMIA: THE ACTIVITY OF CERTAIN TRANSPORTING ENZYMES AND MYOFIBRILLAR CALCIUM-BINDING PROTEIN CONTENT IN THE MUSCLE FIBRE

1982 • 6 citations

An Automatic Nonrebreathing Valve of New Design

1965 • 6 citations

RELATION OF ATPase ACTIVITY AND CALCIUM UPTAKE TO POSTMORTEM GLYCOLYSIS

1971 • 6 citations

Anaesthetic and surgical technique for bilateral adrenalectomy in stress sensitive pigs

1977 • 6 citations

Calcium Ion-Induced Loss of Respiratory Control in Rat Liver Mitochondria in the Presence of Inhalational Anaesthetic Agents

1973 • 5 citations

Calmodulin and malignant hyperpyrexia

1984 • 5 citations

In vivo neutron activation analysis for bone calcium (INVAA) in malignant hyperthermia susceptible patients

1979 • 5 citations

Hepatic Metabolism in Pig Malignant Hyperthermia

1978 • 4 citations

Perfusion of malignant hyperthermia susceptible and normal isolated pig livers with halothane

1978 • 4 citations

Effect of halothane on adenylate kinase in porcine malignant hyperpyrexia

1982 • 4 citations

METABOLISM OF MONOAMINES IN MALIGNANT HYPERTHERMIA-SUSCEPTIBLE PIGS

1982 • 4 citations

THE EFFECT OF THE CALCIUM ION ANTAGONIST 8‐(N,N‐DIETHYLAMINO)‐OCTYL‐3,4,5‐TRIMETHOXYBENZOATEON MALIGNANT HYPERPYREXIA‐SUSCEPTIBLE PORCINE SKELETAL MUSCLE

1983 • 3 citations

Current topics in nerve and muscle research : selected papers of the symposia held at the IVth International Congress on Neuromuscular Diseases, Montreal, Canada, September 17-21, 1978

1979 • 3 citations

[Malignant hyperthermia. III. Progress report on serum CK activity, questionable screening test, effect of dantrolene in family members with a hereditary disposition].

1983 • 2 citations