Applicability of Bacterial Models of DNA Repair and Recovery to UV-Irradiated Mammalian Cells

Defective Repair Replication of DNA in Xeroderma Pigmentosum

1968 • 1,739 citations

Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiation

1968 • 1,089 citations

THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM

1964 • 987 citations

Xeroderma Pigmentosum

1974 • 755 citations

RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12

1964 • 710 citations

Molecular Mechanisms for Repair of DNA

1975 • 676 citations

Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.

1975 • 617 citations

Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli

1971 • 582 citations

DNA Repair and Genetic Recombination: Studies on Mutants of Escherichia coli Defective in These Processes

1966 • 554 citations

A model for replication repair in mammalian cells

1976 • 443 citations

Postreplication repair of DNA in ultraviolet-irradiated mammalian cells

1972 • 439 citations

XERODERMA PIGMENTOSUM: BIOCHEMICAL AND GENETIC CHARACTERISTICS

1975 • 406 citations

Thymine Dimers and Inhibition of DNA Synthesis by Ultraviolet Irradiation of Cells

1963 • 344 citations

Genetic Heterogeneity of Xeroderma Pigmentosum demonstrated by Somatic Cell Hybridization

1972 • 319 citations

Evidence for Excision of Ultraviolet-Induced Pyrimidine Dimers from the DNA of Human Cells In Vitro

1968 • 304 citations

Interactions between twisted DNAs and enzymes: The effects of superhelical turns

1974 • 258 citations

Repair Processes for Photochemical Damage in Mammalian Cells

1974 • 245 citations

Xeroderma Pigmentosum: Variants with Normal Dna Repair and Normal Sensitivity to Ultraviolet Light

1972 • 244 citations

Repair Replication, Unscheduled DNA Synthesis, and the Repair of Mammalian DNA

1969 • 242 citations

Single strand interruptions in DNA and the effects of caffeine in Chinese hamster cells irradiated with ultraviolet light

1969 • 221 citations

Evidence for Dark-Reactivation of Ultraviolet Light Damage in Mouse L Cells

1967 • 216 citations

Normal and Defective Repair of Damaged DNA in Human Cells: A Sensitive Assay Utilizing the Photolysis of Bromodeoxyuridine

1971 • 212 citations

Enzymatic Repair of DNA

1975 • 211 citations

Cleavage of Circular, Superhelical Simian Virus 40 DNA to a Linear Duplex by S ₁ Nuclease

1973 • 207 citations

DNA Damage and Repair in Light-Sensitive Human Skin Disease

1970 • 198 citations

GROWTH, RESPIRATION, AND NUCLEIC ACID SYNTHESIS IN ULTRAVIOLET-IRRADIATED AND IN PHOTOREACTIVATED ESCHERICHIA COLI

1953 • 198 citations

Use of a UV endonuclease from Micrococcus luteus to monitor the progress of DNA repair in UV-irradiated human cells

1973 • 196 citations

Extracellular nucleases of Pseudomonas BAL 31. I. Characterization of single strand-specific deoxyriboendonuclease and double-strand deoxyriboexonuclease activities

1975 • 190 citations

ABSENCE OF EXCISION OF ULTRAVIOLET‐INDUCED CYCLOBUTANE DIMERS IN XERODERMA PIGMENTOSUM*

1970 • 174 citations

National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014, USA.

1975 • 170 citations

DNA Repair and Radiation Sensitivity in Human (Xeroderma Pigmentosum) Cells

1970 • 168 citations

Defective thymine dimer excision by cell-free extracts of xeroderma pigmentosum cells.

1976 • 166 citations

Post‐Replication Repair of DNA in Ultraviolet‐Irradiated Mammalian Cells

1972 • 157 citations

Effects of ultraviolet radiation on macromolecular synthesis in Escherichia coli

1966 • 148 citations

Reactivation After Photobiological Damage

1966 • 136 citations

Photoreactivating enzyme from human leukocytes

1974 • 127 citations

Studies on repair of adenovirus 2 by human fibroblasts using normal, xeroderma pigmentosum, and xeroderma pigmentosum heterozygous strains.

1974 • 121 citations

Ultraviolet-stimulated thymidine incorporation in xeroderma pigmentosum lymphocytes.

1971 • 119 citations

Screening Tests in Chemical Carcinogenesis

1976 • 115 citations

Postreplication repair of DNA in mammalian cells

1974 • 114 citations

Molecular Mechanisms for Repair of DNA

1975 • 113 citations

Decreased Host Cell Reactivation of Irradiated SV40 Virus in Xeroderma Pigmentosum

1970 • 104 citations

T4-endonuclease V-sensitive sites in DNA from ultraviolet-irradiated human cells

1976 • 104 citations

Gaps in DNA synthesized by ultraviolet light-irradiated WI38 human cells

1976 • 101 citations

Purification and characterization of an endonuclease from calf thymus acting on irradiated DNA

1975 • 93 citations

Comparative studies of host-cell reactivation, colony forming ability and excision repair after UV irradiation of xeroderma pigmentosum, normal human and some other mammalian cells

1974 • 91 citations

Xeroderma pigmentosum cells contain low levels of photoreactivating enzyme.

1975 • 90 citations

Biology of radiation carcinogenesis

1976 • 90 citations

Sensitivity of superhelical DNA to a single-strand specific endonuclease

1973 • 88 citations

Host-cell reactivation in mammalian cells. II. Survival of herpes simplex virus and vaccinia virus in normal human and xeroderma pigmentosum cells.

1972 • 84 citations

A third complementation group in xeroderma pigmentosum

1974 • 83 citations

Host-cell Reactivation in Mammalian Cells

1972 • 83 citations

Deoxyribonucleic Acid Synthesis in Ultraviolet-Light-Irradiated Chinese Hamster Cells

1971 • 83 citations

UV-induced DNA repair synthesis in cells of patients with different forms of xeroderma pigmentosum and of heterozygotes

1973 • 81 citations

Recovery of the Ability to Synthesize DNA in Segments of Normal Size at Long Times After Ultraviolet Irradiation of Human Cells

1973 • 79 citations

Host-cell Reactivation in Mammalian Cells

1971 • 79 citations

Effect of monochromatic ultraviolet light on macromolecular synthesis in Escherichia coli

1960 • 76 citations

THE FATE OF PYRIMIDINE DIMERS IN THE DNA OF ULTRAVIOLET‐IRRADIATED CHINESE HAMSTER CELLS

1974 • 76 citations

Purification and some properties of a mammalian repair endonuclease

1974 • 76 citations

CELLULAR REACTIVATION OF ULTRAVIOLET‐IRRADIATED HUMAN ADENOVIRUS 2 IN NORMAL AND XERODERMA PIGMENTOSUM FIBROBLASTS

1974 • 74 citations

Host-cell Reactivation in Mammalian Cells

1972 • 72 citations

DNA DAMAGE AND REPAIR IN EUKARYOTIC CELLS

1974 • 71 citations

Xeroderma pigmentosum variants have decreased repair of ultraviolet-damaged DNA

1975 • 70 citations

Evaluation of S phase synchronization by analysis of DNA replication in 5-bromodeoxyuridine

1973 • 68 citations

Enzymes Involved in the Repair of DNA

1974 • 59 citations

Comparison of the effect of ultraviolet radiation and ethidium bromide intercalation on the conformation of superhelical φX174 replicative form DNA

1973 • 59 citations

A UV-specific endonucleolytic activity present in human cell extracts

1972 • 53 citations

Different ultraviolet DNA endonuclease activity in human cells

1975 • 53 citations

Repair Enzyme suggested by Mammalian Endonuclease Activity specific for Ultraviolet-irradiated DNA

1972 • 51 citations

Nascent DNA synthesis in ultraviolet light-irradiated mouse L cells

1972 • 49 citations

DNA Repair in Potorous tridactylus

1974 • 49 citations

DNA Repair in Chinese Hamster Cells of Different Sensitivities to Ultra-violet Light

1969 • 48 citations

DNA Repair in Human Leukaemic Lymphocytes

1972 • 48 citations

DNA synthesis in sensitive and resistant mutants of Escherichia coli B after ultraviolet irradiation

1969 • 47 citations

Growth of Ultraviolet-Damaged Herpesvirus in Xeroderma Pigmentosum Cells

1969 • 46 citations

Action of single-strand specific Neurospora crassa endonuclease on ultraviolet light-irradiated native DNA

1973 • 45 citations

Significance of dimers to the size of newly synthesized DNA in UV-irradiated Chinese hamster ovary cells

1976 • 44 citations

Cleavage of ultraviolet light-irradiated DNA by single strand-specific S1 endonuclease

1974 • 44 citations

Photoreactivation and Excision Repair of Ultraviolet Radiation-Injured DNA in Primary Embryonic Chick Cells

1974 • 44 citations

Photoreactivation of pyrimidine dimers in the DNA of normal and xeroderma pigmentosum cells

1976 • 43 citations

Effects of ultraviolet irradiation on the rate and sequence of DNA replication in synchronized Chinese hamster cells

1976 • 43 citations

Recovery of Chinese Hamster Cells from Ultra-violet Irradiation Damage

1970 • 41 citations

Biology of Radiation Carcinogenesis

1976 • 41 citations

Screening Tests in Chemical Carcinogenesis

1977 • 40 citations

DNA REPAIR OF ULTRAVIOLET‐IRRADIATED BACTERIOPHAGE T4

1975 • 38 citations

Nascent DNA Synthesis in Ultraviolet Light-Irradiated Mouse, Human, and Chinese Hamster Cells

1974 • 38 citations

Postreplication repair of DNA in chick cells: Studies using photoreactivation

1975 • 38 citations

DNA Repair: A Simple Enzymatic Assay for Human Cells

1973 • 37 citations

Fractionated Ultraviolet Light Irradiation of Cultured Chinese Hamster Cells

1973 • 33 citations

Repair Endonuclease-sensitive Sites in Daughter DNA of Ultraviolet-irradiated Human Cells

1973 • 32 citations

Post-Irradiation Properties of Cultured Chinese Hamster Cells Exposed to Ultraviolet Light

1969 • 31 citations

Relationship of DNA repair to carcinogenesis in xeroderma pigmentosum.

1973 • 31 citations

Cell Cycle Specific Recovery from Fractionated Exposures of Ultraviolet Light

1973 • 31 citations

Low levels of photoreactivating enzyme in xeroderma pigmentosum variants

1975 • 27 citations

Partial purification of endonuclease activity from human lymphoblasts Separation of activities for depurinated DNA and DNA irradiated with ultraviolet light

1975 • 27 citations

Photoreactivation and repair replication in rat kangaroo cells

1973 • 26 citations

Ultraviolet-induced changes in DNA: Possible confusion of repair and degradative enzymes

1973 • 24 citations

The recovery of normal DNA replication kinetics in ultraviolet-irradiated Chinese hamster cells

1977 • 23 citations

Photoreactivation in animal cells

1975 • 21 citations

Some properties of a DNA-unwinding protein unique to lymphocytes from chronic lymphocytic leukemia.

1975 • 20 citations

Strand separation of DNA induced by ultraviolet irradiation in vitro

1974 • 18 citations

Electron Transfer in Gamma-irradiated Complexes between DNA Nucleotides and Proflavine

1970 • 17 citations

Relation Between Survival and Deoxyribonucleic Acid Replication in Ultraviolet-Irradiated Resistant and Sensitive Strains of Escherichia coli B/r

1973 • 16 citations

Influence of ultraviolet irradiation on chromosome replication in ultraviolet-sensitive bacteria

1971 • 14 citations

Host-cell Reactivation in Mammalian Cells

1974 • 12 citations

A deoxyribonuclease activity of HeLa cells specific for UV-irradiated DNA

1971 • 11 citations

Chapter 7 Evaluation of S Phase Synchronization by Analysis of DNA Replication in 5-Bromodeoxyuridine

1975 • 10 citations

An Anomalous Effect of Hydroxyurea and Visible Light on Nucleic Acids of a Photoreactivating Mammalian CellPotorous Tridactylis

1972 • 6 citations

Survival-related DNA repair phenomena in cultured rat-kangaroo cells

1976 • 5 citations