Characterization of the telomeric region of human chromosome 16p

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Structure and function of telomeres

1991 • 3,524 citations

CpG Islands in vertebrate genomes

1987 • 3,315 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

A genetic linkage map of the human genome

1987 • 913 citations

Structure and variability of human chromosome ends.

1990 • 833 citations

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

1990 • 477 citations

A review of the molecular genetics of the human alpha-globin gene cluster

1989 • 443 citations

A review of the molecular genetics of the human alpha-globin gene cluster

1989 • 427 citations

Structure and polymorphism of human telomere-associated DNA

1990 • 382 citations

The highest gene concentrations in the human genome are in telomeric bands of metaphase chromosomes.

1992 • 342 citations

A major positive regulatory region located far upstream of the human alpha-globin gene locus.

1990 • 337 citations

Human telomeres are attached to the nuclear matrix.

1992 • 334 citations

Clustering of hypervariable minisatellites in the proterminal regions of human autosomes

1988 • 292 citations

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

1990 • 288 citations

Gene conversion, recombination nodules, and the initiation of meiotic synapsis

1987 • 203 citations

Characterization of the Major Regulatory Element Upstream of the Human a-Globin Gene Cluster

1991 • 175 citations

Stable length polymorphism of up to 260 kb at the tip of the short arm of human chromosome 16

1991 • 165 citations

Cis-acting sequences regulating expression of the human α-globin cluster lie within constitutively open chromatin

1992 • 162 citations

Cloning human telomeric DNA fragments into Saccharomyces cerevisiae using a yeast-artificial-chromosome vector.

1989 • 150 citations

Further studies on chiasma distribution and interference in the human male

1985 • 116 citations

Characterization of the major regulatory element upstream of the human alpha-globin gene cluster.

1991 • 107 citations

The structure of a subterminal repeated sequence present on many human chromosomes

1990 • 100 citations

The gene for autosomal dominant polycystic kidney disease lies in a 750-kb CpG-rich region

1992 • 83 citations

DETECTION OF BREAKPOINTS IN SUBMICROSCOPIC CHROMOSOMAL TRANSLOCATION, ILLUSTRATING AN IMPORTANT MECHANISM FOR GENETIC DISEASE

1989 • 82 citations

Isolation and characterization of a human telomere

1989 • 78 citations

Identification of a locus which shows no genetic recombination with the autosomal dominant polycystic kidney disease gene on chromosome 16.

1990 • 69 citations

Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)_n

1990 • 53 citations

A long-range restriction map between the α-globin complex and a marker closely linked to the polycystic kidney disease 1 (PKD1) locus

1990 • 52 citations

Asymmetry in chromosome pairing: a major factor in de novo mutation and the production of genetic disease in man.

1989 • 48 citations

Simultaneous genetic mapping of multiple human minisatellite sequences using DNA fingerprinting

1989 • 32 citations

Long range genome structure around the human α-globin complex analysed by PFGE

1987 • 26 citations

An unusually large (CA)n repeat in the region of divergence between subtelomeric alleles of human chromosome 16p

1992 • 16 citations

A low-copy repeat located in subtelomeric regions of 14 different human chromosomal termini

1991 • 14 citations