Expression and Development of Macrophage Activation for Tumor Cytotoxicity

The Macrophage as an Effector Cell

1980 • 628 citations

NK Cells and Other Natural Effector Cells

1982 • 624 citations

Immunobiology of the Macrophage

1976 • 622 citations

The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages

1980 • 543 citations

Endotoxin and Double Stranded RNA render Macrophages Cytotoxic

1971 • 448 citations

Possible Role of Macrophage Mediated Nonspecific Cytotoxicity in Tumour Resistance

1972 • 376 citations

Fluidity of Cell Membranes—Current Concepts and Trends

1979 • 258 citations

Effector mechanisms of cytolytically activated macrophages. II. Secretion of a cytolytic factor by activated macrophages and its relationship to secreted neutral proteases.

1980 • 206 citations

Effector mechanisms of cytolytically activated macrophages. I. Secretion of neutral proteases and effect of protease inhibitors.

1980 • 194 citations

Role of oxygen-dependent mechanisms in antibody-induced lysis of tumor cells by activated macrophages

1980 • 192 citations

Functional characterization of a stable, noncytolytic stage of macrophage activation in tumors.

1977 • 187 citations

Protease inhibitors antagonize the activation of polymorphonuclear leukocyte oxygen consumption

1979 • 150 citations

The Functions of the Macrophage in Malignant Disease

1976 • 119 citations

Receptors for Maleylated Proteins Regulate Secretion of Neutral Proteases by Murine Macrophages

1982 • 112 citations

Mechanisms of Extracellular Killing of Nucleated Mammalian Cells by Macrophages

1976 • 100 citations

Sequential activation of murine mononuclear phagocytes for tumor cytolysis: differential expression of markers by macrophages in the several stages of development.

1983 • 96 citations

Evidence for a multistep mechanism of cytolysis by BCG-activated macrophages: the interrelationship between the capacity for cytolysis, target binding, and secretion of cytolytic factor.

1981 • 81 citations

Interaction of Bacillus Calmette-Guérin-activated macrophages and neoplastic cells in vitro

1980 • 69 citations

Mechanisms of target recognition and destruction in macrophage-mediated tumor cytotoxicity.

1982 • 62 citations

Hydrogen peroxide and cytolytic factor can interact synergistically in effecting cytolysis of neoplastic targets.

1981 • 57 citations

Interaction of Bacillus Calmette-Guérin-activated macrophages and neoplastic cells in vitro

1980 • 53 citations

Increased binding of tumor cells by macrophages activated in vitro with lymphocyte mediators

1978 • 49 citations

The capacity of activated murine macrophages for augmented binding of neoplastic cells: analysis of induction by lymphokine containing MAF and kinetics of the reaction.

1982 • 38 citations

The binding of tumor cells by murine mononuclear phagocytes can be divided into two qualitatively distinct types.

1983 • 36 citations

The binding of BCG-activated macrophages to tumor targets stimulates secretion of cytolytic factor.

1981 • 36 citations

Distinction of Receptor from Nonreceptor Interactions in Binding Studies

1979 • 35 citations

Characterization of genetic defects in macrophage tumoricidal capacity: identification of murine strains with abnormalities in secretion of cytolytic factors and ability to bind neoplastic targets.

1981 • 33 citations

Macrophage activation for tumor cytotoxicity: analysis of intermediary reactions.

1979 • 30 citations

Effect of pyran copolymer on activation of murine macrophages: evidence for incomplete activation by use of functional markers.

1983 • 26 citations

Binding of bacillus Calmette-Guérin-activated macrophages to tumor targets. Selective inhibition by membrane preparations from homologous and heterologous neoplastic cells.

1981 • 20 citations

Macrophage Activation

1984 • 17 citations

The role of transmethylation reactions in regulating the binding of BCG-activated murine macrophages to neoplastic target cells.

1981 • 17 citations

THE RELATIONSHIP BETWEEN SECRETION OF A NOVEL CYTOLYTIC PROTEASE AND MACROPHAGE-MEDIATED TUMOR CYTOTOXICITY

1982 • 8 citations

ANALYSIS OF MACROPHAGE ACTIVATION AND BIOLOGICAL RESPONSE MODIFIER EFFECTS BY USE OF OBJECTIVE MARKERS TO CHARACTERIZE THE STAGES OF ACTIVATION

1982 • 7 citations