The Pathology of Asthma: An Overview

Fibronectins—adhesive glycoproteins of cell surface and blood

1978 • 1,418 citations

Fibronectins: multifunctional modular glycoproteins.

1982 • 1,334 citations

Damage of the Airway Epithelium and Bronchial Reactivity in Patients with Asthma

1985 • 1,315 citations

Cellular Events in the Bronchi in Mild Asthma and after Bronchial Provocation

1989 • 1,158 citations

Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions.

1985 • 1,065 citations

THE PATHOLOGY OF ASTHMA, WITH SPECIAL REFERENCE TO CHANGES IN THE BRONCHIAL MUCOSA

1960 • 1,014 citations

Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection.

1976 • 999 citations

Eosinophils and Mast Cells in Bronchoalveolar Lavage in Subjects with Mild Asthma: Relationship to Bronchial Hyperreactivity

1988 • 905 citations

Bronchoalveolar lavage

2012 • 873 citations

MALARIAL DIABETES

1948 • 829 citations

A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema

1969 • 704 citations

ASTHMA AS AN AXON REFLEX

1986 • 676 citations

Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma

1988 • 635 citations

The eosinophil and the pathophysiology of asthma

1986 • 609 citations

The late phase of the immediate wheal and flare skin reaction. Its dependence upon IgE antibodies.

1976 • 545 citations

THE PATHOLOGY OF BRONCHIAL ASTHMA

1922 • 543 citations

IDENTIFICATION BY IMMUNOFLUORESCENCE OF EOSINOPHIL GRANULE MAJOR BASIC PROTEIN IN LUNG TISSUES OF PATIENTS WITH BRONCHIAL ASTHMA

1982 • 522 citations

Capsaicin-induced desensitization of airway mucosa to cigarette smoke, mechanical and chemical irritants

1983 • 495 citations

Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4.

1983 • 484 citations

Distribution of Fibronectin During Wound Healing in Vivo

1981 • 474 citations

Bronchoalveolar Lavage

1986 • 387 citations

The bronchial circulation. Small, but a vital attribute of the lung.

1987 • 377 citations

Importance of airway inflammation for hyperresponsiveness induced by ozone.

1983 • 369 citations

Activation of Pulmonary Mast Cells by Bronchoalveolar Allergen Challenge:In VivoRelease of Histamine and Tryptase in Atopic Subjects with and without Asthma

1988 • 352 citations

Morphological studies of bronchial mucosal biopsies from asthmatics before and after ten years of treatment with inhaled steroids

1988 • 341 citations

Nonadrenergic inhibitory nervous system in human airways

1976 • 335 citations

Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma.

1981 • 314 citations

Ultrastructure of airways in children with asthma

1978 • 311 citations

Bronchoalveolar Neutrophilia during Late Asthmatic Reactions Induced by Toluene Diisocyanate

1987 • 309 citations

Nerve supply to the lungs.

1979 • 271 citations

A Clinical and Pathological Study of Fatal Cases of Status Asthmaticus

1953 • 258 citations

Bronchoalveolar mast cells in extrinsic asthma: a mechanism for the initiation of antigen specific bronchoconstriction.

1985 • 254 citations

The Shedding of the Mucosa of the Bronchial Tree in Asthma

1962 • 252 citations

Autonomic Regulation of the Airways

1984 • 229 citations

ROLE OF PLASMA EXUDATION IN ASTHMATIC AIRWAYS

1986 • 227 citations

Regeneration of hamster tracheal epithelium after mechanical injury

1982 • 225 citations

Neuro‐epithelial bodies (neuroreceptor or Secretory Organs?) in Human Infant Bronchial and Bronchiolar Epithelium

1972 • 221 citations

Purification and synthesis of eosinophilotactic tetrapeptides of human lung tissue: identification as eosinophil chemotactic factor of anaphylaxis.

1975 • 217 citations

Hyperplasia of bronchial muscle in asthma

1973 • 202 citations

Bronchial Biopsy in Chronic Bronchitis and Asthma

1960 • 200 citations

A COMPARISON BETWEEN CLINICAL, ROENTGENOLOGIC, FUNCTIONAL AND MORPHOLOGIC CRITERIA IN CHRONIC BRONCHITIS, EMPHYSEMA, ASTHMA AND BRONCHIECTASIS

1970 • 194 citations

Mast cells in bronchoalveolar lumen of patients with bronchial asthma.

1984 • 188 citations

Functional assessment of alveolar macrophages: comparison of cells from asthmatics and normal subjects

1982 • 181 citations

Substance P-, VIP-, and enkephalin-like immunoreactivity in the human vagus nerve

1979 • 178 citations

The Respiratory Epithelium

1986 • 159 citations

Muscle and Mucous Gland Size in the Major Bronchi of Patients with Chronic Bronchitis, Asthma, and Asthmatic Bronchitis^1–3

1971 • 159 citations

VIP like immunoreactive nerves in human respiratory tract

1985 • 151 citations

The innervation of the human lung

1933 • 147 citations

Histamine and interstitial Pulmonary Edema in the Dog

1971 • 144 citations

Neurogenic Inflammation in the Respiratory Tract: Actions of Sensory Nerve Mediators on Blood Vessels and Epithelium of the Airway Mucosa

1987 • 136 citations

Plasma exudation and asthma

1988 • 125 citations

Inflammation and asthma

1984 • 123 citations

Regeneration of tracheal epithelium

1953 • 117 citations

Effect of ozone on bronchomotor response to inhaled histamine aerosol in dogs

1977 • 117 citations

The Respiratory Epithelium. VII. Epidermoid Metaplasia of Hamster Tracheal Epithelium During Regeneration Following Mechanical Injury<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1979 • 116 citations

Quantitative Structural Alterations in Long-Standing Allergic Asthma

1984 • 116 citations

Catecholamine- and acetylcholinesterase-containing nerves in human lower respiratory tract

1982 • 108 citations

Fibronectin in delayed-type hypersensitivity skin reactions: associations with vessel permeability and endothelial cell activation.

1981 • 105 citations

Innervation of rabbit intrapulmonary neuroepithelial bodies

1985 • 105 citations

Respiratory Tract Infections Increase Susceptibility to Neurogenic Inflammation in the Rat Trachea

1988 • 104 citations

The biologic activity of mast cell granules. I. Elicitation of inflammatory responses in rat skin.

1980 • 104 citations

Adrenergic and non-adrenergic inhibitory nerves in mammalian airways

1982 • 101 citations

Fatal Bronchial Asthma: A Series of Fifteen Cases with a Review of the Literature

1953 • 94 citations

Effects of inflammatory and other mediators on airway vascular beds.

1987 • 93 citations

The effect of acute airway inflammation on bronchial reactivity in guinea pigs.

1985 • 93 citations

Gross and subgross anatomy of bronchial circulation in sheep

1984 • 89 citations

Charcot-Leyden crystal protein and eosinophil granule major basic protein in sputum of patients with respiratory diseases.

1984 • 86 citations

A comparison of in vivo and in vitro human airway reactivity to histamine.

1984 • 85 citations

Histamine and metacholine challenge in the testing of bronchial reactivity.

1974 • 85 citations

The bronchopulmonary venous collateral circulation with special reference to emphysema.

1953 • 84 citations

Immunohistochemical and biochemical detection of uridine-diphosphate-glucuronyltransferase (UDP-GT) activity in putative preneoplastic liver foci

1982 • 83 citations

Regeneration of hamster tracheal epithelium after mechanical injury

1982 • 80 citations

THE INNERVATION OF THE HUMAN LUNG.

1964 • 79 citations

Disturbances of the ciliated epithelium due to influenza virus.

1966 • 77 citations

Nonspecific Airway Reactivity in Cigarette Smokers

1986 • 75 citations

The sputum in bronchial asthma: Pathognomonic patterns

1965 • 74 citations

Bronchial hyperreactivity occurs in steroid-treated guinea pigs depleted of leukocytes by cyclophosphamide

1985 • 71 citations

THE INTRINSIC NERVOUS MECHANISM OF THE HUMAN LUNG

1934 • 71 citations

Stimulus specificity of the generation of leukotrienes by dog mastocytoma cells.

1983 • 71 citations

The epithelial innervation of the lower respiratory tract of the cat.

1978 • 69 citations

Observations on the Normal Anatomy of the Bronchial Arteries

1951 • 67 citations

HUMORAL CONTROL OF AIRWAYS*

1974 • 65 citations

The biologic activity of mast cell granules. III. Purification of inflammatory factors of anaphylaxis (IF-A) responsible for causing latephase reactions.

1981 • 63 citations

Bronchial mucosal cells.

1979 • 60 citations

The relationship between bronchial hyperresponsiveness to methacholine and airway smooth muscle structure and reactivity

1984 • 60 citations

Relationship between tracheal mucosal thickness and vascular resistance in dogs

1986 • 58 citations

Biology and Pathology of the Vessel Wall

1984 • 55 citations

Electron microscopic study on the innervation of the human lower respiratory tract: evidence of adrenergic nerves.

1985 • 55 citations

Ultrastructural organisation of intraepithelial nerves in the human airway tract.

1985 • 55 citations

Intermediate molecular weight eosinophil chemotactic factors in rat peritoneal mast cells: immunologic release, granule association, and demostration of structura heterogeneity.

1978 • 54 citations

The ultrastructure of afferent nerve endings in the avian lung

1974 • 54 citations

Effects of unilateral hypoxia on neuroepithelial bodies in rabbit lungs

1983 • 54 citations

Untitled

1988 • 48 citations

Vascular Actions of Airway Neuropeptides

1987 • 48 citations

Observations on the Anatomy of the Intrasegmental Bronchial Tree

1952 • 45 citations

Eosinophils and Immunologic Lung Disease

1981 • 43 citations

Intermediate Molecular Weight Eosinophil Chemotactic Factors in Rat Peritoneal Mast Cells: Immunologic Release, Granule Association, and Demonstration of Structural Heterogeneity

1978 • 41 citations

The biologic activity of mast cell granules*VIII. In vivo and in vitro characterization of mast cell granule-derived inflammatory factors involved in rat late-phase reactions

1987 • 40 citations

Organisation and structure of the tracheal and bronchial blood vessels in the dog.

1989 • 39 citations

Airway inflammation and autonomic control.

1986 • 38 citations

Eosinophilia and elevated serum levels of eosinophil major basic protein and Charcot-Leyden crystal protein (lysophospholipase) after treatment of patients with Bancroft's filariasis.

1981 • 37 citations

Mucosal inflammation and bronchial hyperreactivity

1988 • 35 citations

Basal Lamina Components in Experimentally Induced Skin Blisters

1981 • 34 citations

Neuroendocrinelike (small granule) epithelial cells of the lung.

1984 • 33 citations

Fibronectin in Formation and Degradation of the Pericellular Matrix

1985 • 32 citations

Bronchial Circulation in Asthma

1985 • 31 citations

Effects of granulocyte depletion on pulmonary responsiveness to aerosol histamine

1984 • 30 citations

Pathological Findings in Deaths from Asthma

1956 • 29 citations

Pharmacological factors influencing permeability of the bronchial microcirculation.

1978 • 23 citations

Anatomie und Pathologie der Arteria bronchialis

1960 • 22 citations

Biopsy Pathology of the Bronchi

1986 • 16 citations

An electron-microscopic study of the airways in patients with farmer's lung.

1982 • 15 citations

Histology and Electron Microscopy

1974 • 14 citations

Asthma and mast cells of bronchial connective tissue

1962 • 14 citations

Bronchial ciliogenesis and oral steroid treatment in patients with asthma

1988 • 14 citations

Control of airway caliber.

1985 • 13 citations

Bronchoalveolar mast cells in extrinsic asthma: A mechanism for the initiation of antigen-specific bronchoconstrictionFlint K, Leung K, Hudspith B, Brostoff J, Pearce F, Johnson N: Br Med J 291:923, 1985

1986 • 11 citations

Biopsy Pathology of the Bronchi

1986 • 11 citations

Metaplastic cells in sputum of patients with ‘pulmonary eosinophilia’

1959 • 9 citations

Morphological changes related to ciliogenesis in the bronchial epithelium in experimental conditions and clinical course of disease.

1987 • 6 citations

Immunoglobulins, complement and arylsulphatase in sputum from chronic bronchitis and other pulmonary diseases.

1978 • 5 citations

Mast cells on the surface of the mucous membrane--a general feature of inflammatory reactions in the nose?

1985 • 4 citations

[Eosinophils and mast cells].

1952 • 3 citations